Previous studies found an association between mindfulness and forgiveness. However, the effects of self-construal on this association are still unclear. In the present study, self-reported forgiveness and a behavioral measure of forgiveness were used to explore the moderating effect of self-construal plays between mindfulness and forgiveness among 126 participants recruited based on their mindfulness scores. Results showed that participants with high level of mindfulness in the interdependent self-construal condition reported greater forgiveness and gave more money donations towards transgressors than those in the independent self-construal condition, while there is no significant difference between interdependent and independent self-construal groups among participants with low level of mindfulness. These findings suggest that self-construal moderates the relationship between mindfulness and interpersonal forgiveness.