Selective Acetylation Of Alcohols Research Articles

Noncross-linked polystyrene nanoencapsulation of ferric chloride: A novel and reusable heterogeneous macromolecular Lewis acid catalyst toward selective acetylation of alcohols, phenols, amines, and thiols

Ferric chloride has been successfully nanoencapsulated for the first time on a non-cross-linked polystyrene matrix as the shell material via the coacervation technique. The resulting polystyrene nanoencapsulated ferric chloride was used as a novel and recyclable macromolecular Lewis acid catalyst for efficient and selective acetylation of various alcohols, phenols, amines, and thiols using acetic anhydride as the acetyl source at room temperature. The non-cross-linked polystyrene/ferric chloride composite nanocapsules were characterized by DR.-UV, ATR-FT-IR, FE-SEM, TEM, EDX, ICP, DLS, and TGA techniques. This polymeric nanocatalyst with the average particle size of 558 nm was stable and can be easily separated from the reaction mixture by simple filtration, recovered, and it is reusable with only minimal loss of Fe(III). The polystyrene-nanoencapsulated FeCl3 (PS-NC/FeCl3) was found to be stable and more active than its unencapsulated counterpart. Moreover, the nanocapsulated catalyst has relatively high TOF. The composite nanocapsules with multiple ferric chloride cores embedded in a non-cross-linked polystyrene shell showed excellent catalytic activity and reusability indicating the permeability of the shells of nanocapsules enabled catalytic reactions.

Preparation and characterization of multi-walled carbon nanotubes (MWCNTs), functionalized with phosphonic acid (MWCNTs–C–PO3H2) and its application as a novel, efficient, heterogeneous, highly selective and reusable catalyst for acetylation of alcohols, phenols, aromatic amines, and thiols

A novel, efficient, heterogeneous, and reusable multi-walled carbon nanotubes (MWCNTs), functionalized with phosphonic acid (MWCNTs–C–PO3H2) has been synthesized. The synthesized CNTs were characterized using some electron microscopic techniques such as scanning electron microscopy (SEM), atomic force microscopy (AFM), Energy dispersive X-ray spectroscopy (EDAX), and also some thermal and spectroscopic methods such as thermogravimetry (TG). The nitrogen adsorption behavior of the MWCNTs–C–PO3H2 catalyst was evaluated using the TG instrumentation system at 25 °C. The catalyst was applied successfully for highly efficient and selective acetylation of alcohols, phenols, thiols and aromatic amines with acetic anhydride at room temperature under solvent-free conditions. The reusability of the catalyst was checked and the recovered catalyst was reused for five runs without significant loss in activity.

V(HSO 4) 3 catalyzed chemoselectivity acetylation of alcohols and phenols in solution and under solvent-free conditions

A variety of alcohols and phenols are efficiently acetylated with acetic anhydride in the presence of a catalytic amount of V(HSO 4) 3 in solution and under solvent free conditions. Mild reaction conditions, high yields of the products, easy procedure and selective acetylation of alcohols and phenols in the presence of amines and thiols are the main advantages of this procedure.

ChemInform Abstract: Studies on Novel Synthetic Methodologies. Part 148. Selective Acetylation of Alcohols, Phenols and Amines and Selective Deprotection of Aromatic Acetates Using Silica‐Supported Phosphomolybdic Acid.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract: Novel Synthetic Methodologies. Part 148. Selective Acetylation of Alcohols, Phenols and Amines and Selective Deprotection of Aromatic Acetates Using Silica‐Supported Phosphomolybdic Acid.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Selective Acetylation of Alcohols and Amines with Ethyl Acetate in the Presence of H6[PMo9V3O40] as the Catalyst.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Highly efficient and selective acetylation of alcohols and phenols with acetic anhydride catalyzed by a high-valent tin(IV) porphyrin, Sn(TPP)(BF 4) 2

Rapid and efficient acetylation of alcohols and phenols with acetic anhydride in the presence of tin(IV) tetraphenylporphyrinato tetrafluoroborate, Sn IV(tpp)(BF 4) 2, as catalyst is reported. The high catalytic activity of this electron-deficient tin(IV) porphyrin can be used to assist the acetylation of not only primary alcohols but also sterically hindered secondary and tertiary alcohols with acetic anhydride. Acetylation of phenols with acetic anhydride was achieved to afford the desired esters efficiently. This catalyst selectively acetylates the alcohols and phenols in the presence of acetals and silyl ethers.

Selective Acetylation of Alcohols and Amines with Ethyl Acetate in the Presence of H6[PMo9V3O40] as the Catalyst

Acetylation of various alcohols and benzyl amine was tested in the presence of H6[PMo9V3O40], a mixed addenda heteropolyacid, in ethyl acetate under reflux condition. Phenols and anilines are not affected under the reaction conditions. Selective transestrification of alcohols can be achieved in the presence of phenol and aniline derivatives using this method.

Potassium Fluoride Assisted Selective Acetylation of Alcohols with Acetic Acid

Potassium fluoride promotes the acetylation of primary and secondary alcohols with acetic acid in excellent yield. Phenols are not affected under this reaction conditions. The groups like double bond, chloro, methoxy, benzyloxy, thiol, and nitro remain unaffected.

CHEMOSELECTIVE ACETYLATION OF ALCOHOLS, AMINES, AND THIOLS WITHOUT CATALYST AND SOLVENT

Microwave induced rapid and selective acetylation of alcohols, amines and thiols with acetic anhydride was carried out under non-catalytic and solvent free conditions.