Selective Acetylation of Alcohols and Amines with Ethyl Acetate in the Presence of H6[PMo9V3O40] as the Catalyst

Abstract

Acetylation of various alcohols and benzyl amine was tested in the presence of H6[PMo9V3O40], a mixed addenda heteropolyacid, in ethyl acetate under reflux condition. Phenols and anilines are not affected under the reaction conditions. Selective transestrification of alcohols can be achieved in the presence of phenol and aniline derivatives using this method.