Selection Model Research Articles

Improved multi-objective method for the selection of driverless taxi site locations

To expedite the large-scale deployment of driverless taxis and advance the autonomous driving industry, research on the location of integrated parking and charging facilities for driverless taxis has emerged as a significant issue in urban traffic. This study employs a progressive “preliminary selection-screening-optimal selection” approach for site selection. First, the preliminary selection of parking sites is conducted by clustering various Points of Interest (POI) types. Subsequently, a multi-objective site selection model is developed to maximize the coverage of demand points, minimize construction costs, address the largest population demands, and minimize the distance between demand points and candidate sites. The improved genetic algorithm NSGA-II is adopted to obtain several Pareto optimal solutions. The evaluation indexes are selected according to operators, users, and the public transport system to estimate the Pareto optimal solutions, and then the final location solution can be obtained. The calculation methods of several key parameters are improved during the modeling process. Location potential and location influence coefficient are selected to adjust the number of driverless taxi parking spaces. Additionally, isochrones drawn based on the actual road network and path planning represent the service range of candidate points. Meanwhile, distance based on actual road network rather than Euclidean distance is introduced to calculate the distance between candidate points. Finally, a case study shows that the method proposed in this study could reduce the total initial travel time to reach the demand points by 64%, which is independent of operational scheduling.

Evaluating Large Language Models for Material Selection

Abstract Material selection is a crucial step in conceptual design due to its significant impact on the functionality, aesthetics, manufacturability, and sustainability impact of the final product. This study investigates the use of Large Language Models (LLMs) for material selection in the product design process and compares the performance of LLMs against expert choices for various design scenarios. By collecting a dataset of expert material preferences, the study provides a basis for evaluating how well LLMs can align with expert recommendations through prompt engineering and hyperparameter tuning. The divergence between LLM and expert recommendations is measured across different model configurations, prompt strategies, and temperature settings. This approach allows for a detailed analysis of factors influencing the LLMs' effectiveness in recommending materials. The results from this study highlight two failure modes, and identify parallel prompting as a useful prompt-engineering method when using LLMs for material selection. The findings further suggest that, while LLMs can provide valuable assistance, their recommendations often vary significantly from those of human experts. This discrepancy underscores the need for further research into how LLMs can be better tailored to replicate expert decision-making in material selection. This work contributes to the growing body of knowledge on how LLMs can be integrated into the design process, offering insights into their current limitations and potential for future improvements.

Fuzzy Logic Model for Selection of Performance Upgrade Alternatives in Remanufacturing: Case of Brake Caliper Component

Fuzzy Logic Model for Selection of Performance Upgrade Alternatives in Remanufacturing: Case of Brake Caliper Component

CNN-BiLSTM-Attention Based Stock Price Prediction and Quantitative Investment Strategy

With the rapid development of technology and the increasing maturity of financial markets, stock price prediction has become a hot topic and an important trend in the financial field. However, the stock market has complexity and volatility, in order to reduce the investment risk and ensure the maximization of benefits, selecting the optimal stock to predict the stock price and formulating the quantitative trading strategy are extremely important issues for financial academics and investors. For the research of stock price prediction and quantitative trading, firstly, the quantitative stock selection model combining XGBoost and multi-factor stock selection model is constructed, and four stocks are screened out, and then the CNN-BiLSTM-Attention model is proposed to predict the stock price trend of the selected stocks, and it is found from the prediction results of the four stocks that the prediction accuracies all reach more than 95%, which is higher than that of the single model prediction. accuracy and passed the validity test of the fitted model. Secondly, based on the quantitative investment portfolio given in the above analysis and the quantitative stock trading strategy of MACD, the prediction results are verified, and the total return of most stocks based on the strategy is higher than 40% at the highest, and the loss is controlled within 10%, which indicates that the trading strategy in this paper is effective and feasible. The study concludes that greater returns can be obtained by calculating the total returns of stock portfolios based on different portfolio approaches.

Detection of Thymoma Disease Using mRMR Feature Selection and Transformer Models

Background: Thymoma is a tumor that originates in the thymus gland, a part of the human body located behind the breastbone. It is a malignant disease that is rare in children but more common in adults and usually does not spread outside the thymus. The exact cause of thymic disease is not known, but it is thought to be more common in people infected with the EBV virus at an early age. Various surgical methods are used in clinical settings to treat thymoma. Expert opinion is very important in the diagnosis of the disease. Recently, next-generation technologies have become increasingly important in disease detection. Today’s early detection systems already use transformer models that are open to technological advances. Methods: What makes this study different is the use of transformer models instead of traditional deep learning models. The data used in this study were obtained from patients undergoing treatment at Fırat University, Department of Thoracic Surgery. The dataset consisted of two types of classes: thymoma disease images and non-thymoma disease images. The proposed approach consists of preprocessing, model training, feature extraction, feature set fusion between models, efficient feature selection, and classification. In the preprocessing step, unnecessary regions of the images were cropped, and the region of interest (ROI) technique was applied. Four types of transformer models (Deit3, Maxvit, Swin, and ViT) were used for model training. As a result of the training of the models, the feature sets obtained from the best three models were merged between the models (Deit3 and Swin, Deit3 and ViT, Deit3 and ViT, Swin and ViT, and Deit3 and Swin and ViT). The combined feature set of the model (Deit3 and ViT) that gave the best performance with fewer features was analyzed using the mRMR feature selection method. The SVM method was used in the classification process. Results: With the mRMR feature selection method, 100% overall accuracy was achieved with feature sets containing fewer features. The cross-validation technique was used to verify the overall accuracy of the proposed approach and 99.22% overall accuracy was achieved in the analysis with this technique. Conclusions: These findings emphasize the added value of the proposed approach in the detection of thymoma.

Prediction Model of Delayed Hemothorax in Patients with Traumatic Occult Hemothorax Using a Novel Nomogram.

Delayed hemothorax (dHTX) can occur unexpectedly, even in patients who initially present without signs of hemothorax (HTX), potentially leading to death. We aimed to develop a predictive model for dHTX requiring intervention, specifically targeting those with no or occult HTX. This retrospective study was conducted at a level 1 trauma center. The primary outcome was the occurrence of dHTX requiring intervention in patients who had no HTX or occult HTX and did not undergo closed thoracostomy post-injury. To minimize overfitting, we employed the least absolute shrinkage and selection operator (LASSO) logistic regression model for feature selection. Thereafter, we developed a multivariable logistic regression (MLR) model and a nomogram. In total, 688 patients were included in the study, with 64 cases of dHTX (9.3%). The LASSO and MLR analyses revealed that the depth of HTX (adjusted odds ratio [aOR], 3.79; 95% confidence interval [CI], 2.10-6.85; p<0.001) and the number of totally displaced rib fractures (RFX) (aOR, 1.90; 95% CI, 1.56-2.32; p<0.001) were significant predictors. Based on these parameters, we developed a nomogram to predict dHTX, with a sensitivity of 78.1%, a specificity of 76.0%, a positive predictive value of 25.0%, and a negative predictive value of 97.1% at the optimal cut-off value. The area under the receiver operating characteristic curve was 0.832. The depth of HTX on initial chest computed tomography and the number of totally displaced RFX emerged as significant risk factors for dHTX. We propose a novel nomogram that is easily applicable in clinical settings.

A new mathematical model and meta-heuristic algorithm for order batching, depot selection, and assignment problem with multiple depots and pickers

The ‘order picking problem’ involves the efficient and organized retrieval of items from shelves to fulfill customer orders. In this study, we consider a new configuration of warehouse system with multiple pickers and depots (m-pickers & n-depots) for manually operated ‘picker-to-parts’ warehouses. The efficiency of the process is measured based on two metrics: i- total order picking distance of each picker ii- total number of pickers assigned to each of depots. The handled problem is called as ‘Order Batching, Depot Selection and Assignment Problem with Multiple Depots and Multiple Pickers (OBDSAPMDMP)11OBDSAPMDMP = Order Batching, Depot Selection, and Assignment Problem with Multiple Depots and Multiple Pickers.’. To solve this complex problem, a new bi-objective Mixed-Integer Linear Programming (MILP) formulation for small-sized problems and a meta-heuristic called ‘Dependent Harmony Search (DHS)22DHS = Dependent Harmony Search.’ for large-sized problems are proposed. The performance of DHS algorithm is evaluated by comparing the optimal results attained by MILP model. For the problem size of 10 orders, the average gap (%) in distance between the solution of DHS and MILP is 4.22%, although in some experiments DHS can find the optimal solution in a very short time. Also, in related analysis, it is seen that constructing multiple depots instead of one left-most located depot decreases total order picking distance by 7.11% on average.

Harnessing probabilistic neural network with triple tree seed algorithm-based smart enterprise quantitative risk management framework

Enterprise risk management (ERM) frameworks convey vital principles that help create a consistent risk management culture, irrespective of employee turnover or industry standards. Enterprise Management System (EMS) are becoming a popular research area for assuring a company’s long-term success. Statistical pattern recognition, federated learning, database administration, visualization technology, and social networking are all used in this field, which includes artificial intelligence (AI), data science, and statistics. Risk assessment in EMS is critical for enterprise decision-making to be effective. Recent advancements in AI, machine learning (ML), and deep learning (DL) concepts have enabled the development of effective risk assessment models for EMS. This special issue seeks groundbreaking research articles that showcase the application of applied probability and statistics to interdisciplinary studies. This study offers Improved Metaheuristics with a Deep Learning Enabled Risk Assessment Model (IMDLRA-SES) for Smart Enterprise Systems. Using feature selection (FS) and DL models, the provided IMDLRA-SES technique estimates business risks. Preprocessing is used in the IMDLRA-SES technique to change the original financial data into a usable format. In addition, an FS technique based on oppositional lion swarm optimization (OLSO) is utilized to find the best subset of features. In addition, the presence or absence of financial hazards in firms is classified using the triple tree seed algorithm (TTSA) with a probabilistic neural network (PNN) model. The TTSA is used as a hyperparameter optimizer to improve the efficiency of the PNN-based categorization. An extensive set of experimental evaluations is performed on German and Australian credit datasets to illustrate the IMDLRA-SES model’s improved performance. The performance validation of the IMDLRA-SES model portrayed a superior accuracy value of 95.70% and 96.09% over existing techniques.

The contributions of direct and indirect selection to the evolution of mating preferences.

Many influential mathematical models of sexual selection have stressed that mating preferences evolve due to correlations that build between mating preferences and preferred display traits - that is, through indirect selection. Nevertheless, there is a perception that indirect selection should generally be overwhelmed by direct selection, for example in the form of search costs. Recent work by Fry has used quantitative genetic models to argue that in many cases, including when there are direct benefits (a fecundity advantage to mating with the preferred male), direct and indirect selection may be of similar magnitude. Here I use population genetic models, in which the strength of the genetic correlation is an emergent property of evolution at mating preference and display trait loci, to assess the relative contributions of direct and indirect selection to the evolution of mating preferences. For the cases of direct benefits and of indirect benefits with fixed and frequency-dependent search costs, I outline parameter values of fecundity benefits, preference strengths, and search costs for which indirect selection on female preferences can potentially predominate. I also analyze male mate choice under polygyny, showing that direct selection will always outweigh indirect selection except when there are direct benefits.

Research on the Location Selection Problem of Electric Bicycle Battery Exchange Cabinets Based on an Improved Immune Algorithm

The rise of new energy technologies has accelerated progress towards sustainable development, and many companies are beginning to invest in renewable resource-related facilities. Electric bicycles have always been an important mode of green transportation; however, they also have problems such as slow charging, difficult charging, and that burning and short circuiting may occur during charging. Electric bicycle battery exchange cabinets effectively solve these problems by exchanging low batteries with full batteries instead of charging. However, current battery exchange cabinets face the problems of insufficient construction and unreasonable site selection. Therefore, this paper proposes a location selection model for electric bicycle battery exchange cabinets based on point demand theory, aiming to maximize rider satisfaction and the service capacity of exchange cabinets. The immune algorithm is introduced to solve the location model; however, the traditional immune algorithm has some problems such as poor stability and slow convergence. In this paper, the mutation process of the traditional immune algorithm is improved by introducing multi-point mutation, guided mutation, and local search. Finally, based on the data of electric bicycle riders in Shanghai, we verify that the location model based on point demand theory performs well on two objective functions of rider satisfaction and battery exchange cabinet service capability. We also expand the application of point demand theory to location models. Then, by conducting experiments with different parameter groups, through sensitivity analysis and convergence analysis, we verified that the improved immune algorithm performs better than the traditional immune algorithm in its accuracy, search accuracy, stability, and convergence.

Measuring and Mitigating Racial Disparities in Tax Audits

Abstract Tax authorities around the world rely on audits to detect underreported tax liabilities and to verify that taxpayers qualify for the benefits they claim. We study differences in Internal Revenue Service audit rates between Black and non-Black taxpayers. Because neither we nor the IRS observe taxpayer race, we propose and use a novel partial identification strategy to estimate these differences. Despite race-blind audit selection, we find that Black taxpayers are audited at 2.9 to 4.7 times the rate of non-Black taxpayers. An important driver of the disparity is differing audit rates by race among taxpayers claiming the Earned Income Tax Credit (EITC). Using counterfactual audit selection models to explore why the disparity arises, we find that maximizing the detection of underreported taxes would not lead to Black EITC claimants being audited at higher rates. Rather, the audit disparity among EITC claimants stems largely from a policy decision to prioritize detecting overclaims of refundable credits over other forms of noncompliance. Modifying the audit selection algorithm to target total underreported taxes while holding fixed the number of audited EITC claimants would reduce the share of audited taxpayers who are Black and would lead to more audits focused on accurate reporting of business income and deductions, fewer audits focused on the eligibility of claimed dependents, higher per audit costs, and more detected noncompliance.

The Cost-Optimal Control of Building Air Conditioner Loads Based on Machine Learning: A Case Study of an Office Building in Nanjing

Building envelopes and indoor environments exhibit thermal inertia, forming a virtual energy storage system in conjunction with the building air conditioner (AC) system. This system represents a current demand response resource for building electricity use. Thus, this study centers on the CatBoost algorithm within machine learning (ML) technology, utilizing the LASSO regression model for feature selection and applying the Optuna framework for hyperparameter optimization (HPO) to develop a cost-optimal control method for minimizing building AC loads. This method addresses the challenges associated with traditional load forecasting and control methods, which are often impacted by environmental temperature, building parameters, and user behavior uncertainties. These methods struggle to accurately capture the complex dynamics and nonlinear relationships of AC operations, making it difficult to devise AC operation and virtual energy storage scheduling strategies effectively. The proposed method was applied and validated using a case study of an office building in Nanjing, China. The prediction results showed coefficient of variation in root mean square error (CV-RMSE) values of 6.4% and 2.2%. Compared with the original operating conditions, the indoor temperature remained within a comfortable range, the AC load was reduced by 5.25%, and the operating energy costs were reduced by 24.94%. These results demonstrate that the proposed method offers improved computational efficiency, enhanced model performance, and economic benefits.

Robust variable selection methods with Cox model-a selective practical benchmark study.

With the advancement of biological and medical techniques, we can now obtain large amounts of high-dimensional omics data with censored survival information. This presents challenges in method development across various domains, particularly in variable selection. Given the inherently skewed distribution of the survival time outcome variable, robust variable selection methods offer potential solutions. Recently, there has been a focus on extending robust variable selection methods from linear regression models to survival models. However, despite these developments, robust methods are currently rarely used in practical applications, possibly due to a limited appreciation of their overall good performance. To address this gap, we conduct a selective review comparing the variable selection performance of twelve robust and non-robust penalised Cox models. Our study reveals the intricate relationship among covariates, survival outcomes, and modeling approaches, demonstrating how subtle variations can significantly impact the performance of methods considered. Based on our empirical research, we recommend the use of robust Cox models for variable selection in practice based on their superior performance in presence of outliers while maintaining good efficiency and accuracy when there are no outliers. This study provides valuable insights for method development and application, contributing to a better understanding of the relationship between correlated covariates and censored outcomes.

Cardiovascular Disease, Brain Glucose Metabolism, and Neurocognitive Decline in People With Human Immunodeficiency Virus.

Cardiovascular disease (CVD) and neuroinflammation are thought to exacerbate neurocognitive dysfunction in treated people with human immunodeficiency virus (PWH). Here, we longitudinally measured brain glucose metabolism as a measure of neuronal integrity in treated PWH using [18F]Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in correlation with atherosclerotic cardiovascular disease (ASCVD) scores, cerebrospinal fluid (CSF) neuroinflammatory markers, neurocognitive outcomes, and other clinical and laboratory variables (CLVs). Well-controlled PWH (n = 36) underwent baseline and follow-up FDG PET/CT obtained 3.5 years apart on average. Longitudinal changes in whole brain and regional relative FDG uptake, brain volumes, CLVs, CSF cytokines, and neuropsychological measures were measured. A variable selection model identified baseline variables related to future brain metabolic changes while multivariable models explored neuropsychological implications of brain metabolism and volumetrics. High ASCVD scores predicted future decreased thalamic uptake (slope = -0.0068, P = .027) and decreasing thalamic uptake correlated with worsening cognition (slope = 15.80, P = .020). Despite longitudinal greater than expected gray matter loss, whole brain FDG uptake did not change over the follow-up period. Most CSF cytokines decreased longitudinally but were not predictive of FDG changes. We found that high ASCVD scores in a group of treated PWH were related to thalamic hypometabolism, which in turn correlated with neurocognitive decline. Our findings support the contribution of CVD to neurocognitive dysfunction. More proactive CVD management may have a role in mitigating progression of cognitive impairment. Lack of change in global brain glucose metabolism despite documented accelerated gray matter volume loss over the same period suggests that FDG PET might underestimate neuronal injury in PWH compared to structural magnetic resonance imaging.

Framework to improve software effort estimation accuracy using novel ensemble rule

This investigation focuses on refining software effort estimation (SEE) to enhance project outcomes amidst the rapid evolution of the software industry. Accurate estimation is a cornerstone of project success, crucial for avoiding budget overruns and minimizing the risk of project failures. The framework proposed in this article addresses three significant issues that are critical for accurate estimation: dealing with missing or inadequate data, selecting key features, and improving the software effort model. Our proposed framework incorporates three methods: the Novel Incomplete Value Imputation Model (NIVIM), a hybrid model using Correlation-based Feature Selection with a meta-heuristic algorithm (CFS-Meta), and the Heterogeneous Ensemble Model (HEM). The combined framework synergistically enhances the robustness and accuracy of SEE by effectively handling missing data, optimizing feature selection, and integrating diverse predictive models for superior performance across varying project scenarios. The framework significantly reduces imputation and feature selection overhead, while the ensemble approach optimizes model performance through dynamic weighting and meta-learning. This results in lower mean absolute error (MAE) and reduced computational complexity, making it more effective for diverse software datasets. NIVIM is engineered to address incomplete datasets prevalent in SEE. By integrating a synthetic data methodology through a Variational Auto-Encoder (VAE), the model incorporates both contextual relevance and intrinsic project features, significantly enhancing estimation precision. Comparative analyses reveal that NIVIM surpasses existing models such as VAE, GAIN, K-NN, and MICE, achieving statistically significant improvements across six benchmark datasets, with average RMSE improvements ranging from 11.05% to 17.72% and MAE improvements from 9.62% to 21.96%. Our proposed method, CFS-Meta, balances global optimization with local search techniques, substantially enhancing predictive capabilities. The proposed CFS-Meta model was compared to single and hybrid feature selection models to assess its efficiency, demonstrating up to a 25.61% reduction in MSE. Additionally, the proposed CFS-Meta achieves a 10% (MAE) improvement against the hybrid PSO-SA model, an 11.38% (MAE) improvement compared to the Hybrid ABC-SA model, and 12.42% and 12.703% (MAE) improvements compared to the hybrid Tabu-GA and hybrid ACO-COA models, respectively. Our third method proposes an ensemble effort estimation (EEE) model that amalgamates diverse standalone models through a Dynamic Weight Adjustment-stacked combination (DWSC) rule. Tested against international benchmarks and industry datasets, the HEM method has improved the standalone model by an average of 21.8% (Pred()) and the homogeneous ensemble model by 15% (Pred()). This comprehensive methodology underscores our model’s contributions to advancing software project management (SPM) through advanced predictive modeling, setting a new benchmark for software engineering effort estimation.

Organizational Selection of Innovation

Budgetary constraints force organizations to pursue only a subset of possible innovation projects. Identifying which subset is most promising is an error-prone exercise, and involving multiple decision makers may be prudent. This raises the question of how to most effectively aggregate their collective nous. Our model of organizational portfolio selection provides some first answers. We show that portfolio performance can vary widely. Delegating evaluation makes sense when organizations employ the relevant experts and can assign projects to them. In most other settings, aggregating the impressions of multiple agents leads to better performance than delegation. In particular, letting agents rank projects often outperforms alternative aggregation rules—including averaging agents’ project scores and counting their approval votes—especially when organizations have tight budgets and can select only a few project alternatives out of many. Funding: L. Böttcher acknowledges financial support from hessian.AI and the Army Research Office [Grant W911NF-23-1-0129]. Supplemental Material: The data files are available at https://doi.org/10.1287/orsc.2023.17357 .

Simultaneous Instance and Attribute Selection for Noise Filtering

The existence of noise is inherent to most real data that are collected. Removing or reducing noise can help classification algorithms focus on relevant patterns, preventing them from being affected by irrelevant or incorrect information. This can result in more accurate and reliable models, improving their ability to generalize and make accurate predictions on new data. For example, among the main disadvantages of the nearest neighbor classifier are its noise sensitivity and its high computational cost (for classification and storage). Thus, noise filtering is essential to ensure data quality and the effectiveness of supervised classification models. The simultaneous selection of attributes and instances for supervised classifiers was introduced in the last decade. However, the proposed solutions present several drawbacks because some are either stochastic or do not handle noisy domains, and the neighborhood selection of some algorithms allows very dissimilar objects to be considered as neighbors. In addition, the design of some methods is just for specific classifiers without generalization possibilities. This article introduces an instance and attribute selection model, which seeks to detect and eliminate existing noise while reducing the feature space. In addition, the proposal is deterministic and does not predefine any supervised classifier. The experiments allow us to establish the viability of the proposal and its effectiveness in eliminating noise.

Cross-ancestry meta-genome-wide association studies provide insights to the understanding of semen traits in pigs

Semen traits play a crucial role in pig reproduction and fertility. However, limited data availability hinder a comprehensive understanding of the genetic mechanisms underlying these traits. In this study, we integrated 597 299 ejaculates and 3 596 sequence data to identify genetic variants and candidate genes related to four semen traits, including sperm progressive motility (MOT), semen volume, sperm concentration (CON), and effective sperm count (SUM). A cross-ancestry meta−genome-wide association study was conducted to detect 163 lead single nucleotide polymorphisms (SNPs) associated with MOT, CON, and SUM. Subsequently, transcriptome-wide association studies and colocalisation analyses were integrated to identify 176 candidate genes, many of which have documented roles in spermatogenesis or male mammal semen traits. Our analysis highlighted the potential involvement of CSM5, PDZD9, and LDAF1 in regulating semen traits through multiple methods. Finally, to validate the function of significant SNPs, we performed genomic feature best linear unbiased prediction in 348 independent pigs using identified trait-related SNP subsets as genomic features. We found that integrating the top 0.1, 1, and 5% significant SNPs as genomic features could enhance genomic prediction accuracy for CON and MOT compared to traditional genomic best linear unbiased prediction. This study contributes to a comprehensive understanding of the genetic mechanisms of boar semen traits and provides insight for developing genomic selection models.

Ultrasound biomicroscopy in dogs suggests postoperative ocular hypertension may be associated with ciliary cleft changes related to cataract surgery.

To determine whether novel pre- and postsurgical ultrasound biomicroscopy (UBM) measurements of the canine ciliary cleft (CC) are associated with postoperative ocular hypertension (POH) following cataract surgery and to explore the relationship between intraocular pressure and CC UBM measurements. Following pharmacologic mydriasis, UBM images were obtained from 31 client-owned dogs before elective cataract surgery, immediately postsurgery, and 4 to 6 hours following surgery or while experiencing POH ≥ 25 mm Hg. Presurgery and the pre- to postsurgery change in CC measurements were assessed for association with POH using individual mixed-effects logistic regression models and forward variable selection models. Linear mixed-effects models were used to evaluate the relationship of intraocular pressure to UBM measurements within the same eye across multiple time points. Presurgical measurements were not predictive of POH development. An increase in pectinate ligament distance and CC area from presurgical baseline to immediate postsurgical measurement was associated with reduced odds of developing POH, while increasing CC length (from apex to mid point on the pectinate ligament) from pre- to postsurgery and immature cataracts was associated with increased odds of POH. The change in CC morphology following cataract surgery appears more impactful in the development of POH than individual variations in presurgery CC measurements. Several changes in the CC dimensions following surgery appear associated with POH risk. This understanding of a potential mechanism of POH development opens new avenues for researching preventative measures associated with modifying surgical techniques to influence CC morphology following cataract surgery.

Resilient roads in challenging terrain: a case study of Siddhartha highway in Nepal

Nepal is a country known for its diverse and challenging topography, and it relies heavily on a robust road infrastructure network to connect its remote regions and urban centers. This study addresses the critical need for enhanced road safety and infrastructure resilience on the Siddhababa road section of the Siddhartha Highway, Nepal, notorious for its high accident rates and susceptibility to landslides. Given the road's strategic importance in connecting remote regions and its challenging topographical conditions, our research aimed to identify the most suitable pavement type to mitigate these issues. Through a detailed examination incorporating eight different soil tests, alongside evaluations of traffic loads, weather conditions, and existing pavement performance, we adopted a comparative analysis methodology to assess the viability of flexible versus rigid pavements within this unique context. Results revealed that the soil composition and environmental conditions of the Siddhababa section significantly influence pavement performance, with specific gravity, moisture content, and California Bearing Ratio (CBR) tests indicating a nuanced suitability for both pavement types under varying circumstances. Our analysis concluded that, despite the economic and staged reinforcement benefits of flexible pavements, the durability, safety, and maintenance considerations favor the adoption of rigid pavement for the Siddhababa road section. However, acknowledging the economic constraints, a hybrid approach is recommended, emphasizing rigid pavements for the most vulnerable sections and flexible pavements elsewhere. This study contributes to the pavement engineering field by providing a model for pavement type selection in mountainous regions, aiming to enhance road safety and durability amidst challenging environmental conditions.