The agricultural sector plays a great role in the economy of several countries and their economic sustainability is also majorly dependent on the agricultural performance of the country. There are various aspects related to agriculture sector that might have the impact on economic sustainability in one way or the other. In continuation of this issue, the researcher has conducted this study so that the impact casted by climate change, agricultural growth, and food production on the economic sustainability of the ASEAN countries can be studied effectively. For this research, the researcher has gathered relevant data from six ASEAN countries i.e. Brunei, Cambodia, Indonesia, Laos, Thailand, and Philippines. The period for which the data has been collected comprises of 29 years. For analysis of this data, the researcher has applied tests such as panel unit root test, panel cointegration test, AMG estimation and panel casualty test and has obtained the desired results. The results make it clear that the independent variables i.e. climate change, agricultural growth and food production have significant impact on economic sustainability for most of the selected ASEAN countries. Moreover, various variables have also shown unidirectional and bidirectional casualty among them.