The main result of the work was the identification of the present-day seismotectonic regime of an active zone of the Lyakhovichi regional fault. The areal and space-time distribution of the earthquake epicenters along the fault line was reconstructed. The coordinates of the seismically active fault zone located within an area of 52.738—53.037° N and 26.830—28.034° E were determined. It was found that the distribution of earthquakes along the fault line occurred non-uniformly in space and time. The period from 2012 till 2021 was the most active one by the quantity of occurred earth quakes (169) and released total seismic energy (4.5929•109 J). The strongest earthquake with a magnitude M = 2.9 was recorded in the eastern part of the fault on September 03, 2021. Our reconstructions determined the value of seismic dislocation along the fault, which corresponded to the kinematic slip fault. To characterize the modern seismogeodynamic activity in the Lyakhovichi fault zone, a comprehensive technique based on long-term monitoring of seismic events was used. Based on the performed studies, the seismotectonic potential of the seismoactive zone of the Lyakhovichi fault was determined.