The estimation of earthquake losses for single layer industrial buildings based stochastic analysis is the focus of the research. An assembly-based mixture vulnerability methodology is firstly adopted for industrial buildings modeling and seismic loss estimation. The damage of the structural and non-structural which connected into response of the factory structures under given stochastic motions use nonlinear time-history analysis to estimate in a detailed. Description of the uncertainty of all parameters in life-cycle seismic cost (LCC) research through appropriate probability distributions to reach quantification of the LCC expected value. Moreover, the study is also to give primary solution that how to calculate the expected suggested insurance premium for simple industrial building stock in seismic prone areas of China based probabilistic seismic risk assessment in its service lifetime.