This paper deals with segregation effects in of binary mixtures in a 2D fluidized bed. In the experiment initial inhomogeneities in the particle mixture lead to uneven bed pressure drop. This results in inhomogeneous particle segregation and the formation of heap like structures. The effect is clearly reproducible for small particle mass fractions of 40 to 60%. A numerical model based on a hybrid DPM/Euler model was developed and shows a similar behaviour for initial disturbances in the binary particle mixture.