Segmentation Labels Research Articles

Instance Segmentation XXL-CT Challenge of a Historic Airplane

Instance segmentation of compound objects in XXL-CT imagery poses a unique challenge in non-destructive testing. This complexity arises from the lack of known reference segmentation labels, limited applicable segmentation tools, as well as partially degraded image quality. To asses recent advancements in the field of machine learning-based image segmentation, the ‘Instance Segmentation XXL-CT Challenge of a Historic Airplane’ was conducted. The challenge aimed to explore automatic or interactive instance segmentation methods for an efficient delineation of the different aircraft components, such as screws, rivets, metal sheets or pressure tubes. We report the organization and outcome of this challenge and describe the capabilities and limitations of the submitted segmentation methods.

Barrier-free tomato fruit selection and location based on optimized semantic segmentation and obstacle perception algorithm.

With the advancement of computer vision technology, vision-based target perception has emerged as a predominant approach for harvesting robots to identify and locate fruits. However, little attention has been paid to the fact that fruits may be obscured by stems or other objects. In order to improve the vision detection ability of fruit harvesting robot, a fruit target selection and location approach considering obstacle perception was proposed. To enrich the dataset for tomato harvesting, synthetic data were generated by rendering a 3D simulated model of the tomato greenhouse environment, and automatically producing corresponding pixel-level semantic segmentation labels. An attention-based spatial-relationship feature extraction module (SFM) with lower computational complexity was designed to enhance the ability of semantic segmentation network DeepLab v3+ in accurately segmenting linear-structured obstructions such as stems and wires. An adaptive K-means clustering method was developed to distinguish individual instances of fruits. Furthermore, a barrier-free fruit selection algorithm that integrates information of obstacles and fruit instances was proposed to identify the closest and largest non-occluded fruit as the optimal picking target. The improved semantic segmentation network exhibited enhanced performance, achieving an accuracy of 96.75%. Notably, the Intersection-over-Union (IoU) of wire and stem classes was improved by 5.0% and 2.3%, respectively. Our target selection method demonstrated accurate identification of obstacle types (96.15%) and effectively excluding fruits obstructed by strongly resistant objects (86.67%). Compared to the fruit detection method without visual obstacle avoidance (Yolo v5), our approach exhibited an 18.9% increase in selection precision and a 1.3% reduction in location error. The improved semantic segmentation algorithm significantly increased the segmentation accuracy of linear-structured obstacles, and the obstacle perception algorithm effectively avoided occluded fruits. The proposed method demonstrated an appreciable ability in precisely selecting and locating barrier-free fruits within non-structural environments, especially avoiding fruits obscured by stems or wires. This approach provides a more reliable and practical solution for fruit selection and localization for harvesting robots, while also being applicable to other fruits and vegetables such as sweet peppers and kiwis.

RPDNet: A reconstruction-regularized parallel decoders network for rectal tumor and rectum co-segmentation

Accurate segmentation of rectal cancer tumor and rectum in magnetic resonance imaging (MRI) is significant for tumor precise diagnosis and treatment plans determination. Variable shapes and unclear boundaries of rectal tumors make this task particularly challenging. Only a few studies have explored deep learning networks in rectal tumor segmentation, which mainly adopt the classical encoder-decoder structure. The frequent downsampling operations during feature extraction result in the loss of detailed information, limiting the network's ability to precisely capture the shape and boundary of rectal tumors. This paper proposes a Reconstruction-regularized Parallel Decoder network (RPDNet) to address the problem of information loss and obtain accurate co-segmentation results of both rectal tumor and rectum. RPDNet initially establishes a shared encoder and parallel decoders framework to fully utilize the common knowledge between two segmentation labels while reducing the number of network parameters. An auxiliary reconstruction branch is subsequently introduced by calculating the consistency loss between the reconstructed and input images to preserve sufficient anatomical structure information. Moreover, a non-parameter target-adaptive attention module is proposed to distinguish the unclear boundary by enhancing the feature-level contrast between rectal tumors and normal tissues. The experimental results indicate that the proposed method outperforms state-of-the-art approaches in rectal tumor and rectum segmentation tasks, with Dice coefficients of 84.91 % and 90.36 %, respectively, demonstrating its potential application value in clinical practice.

D2-SPDM: Faster R-CNN-Based Defect Detection and Surface Pixel Defect Mapping with Label Enhancement in Steel Manufacturing Processes

The steel manufacturing process is inherently continuous, meaning that if defects are not effectively detected in the initial stages, they may propagate through subsequent stages, resulting in high costs for corrections in the final product. Therefore, detecting surface defects and obtaining segmentation information is critical in the steel manufacturing industry to ensure product quality and enhance production efficiency. Specifically, segmentation information is essential for accurately understanding the shape and extent of defects, providing the necessary details for subsequent processes to address these defects. However, the time-consuming and costly process of generating segmentation annotations poses a significant barrier to practical industrial applications. This paper proposes a cost-efficient segmentation labeling framework that combines deep learning-based anomaly detection and label enhancement to address these challenges in the steel manufacturing process. Using ResNet-50, defects are classified, and faster region convolutional neural networks (faster R-CNNs) are employed to identify defect types and generate bounding boxes indicating the defect locations. Subsequently, recursive learning is performed using the GrabCut algorithm and the DeepLabv3+ model based on the generated bounding boxes, significantly reducing annotation costs by generating segmentation labels. The proposed framework effectively detects defects and accurately defines them, even in randomly collected images from the steel manufacturing process, contributing to both quality control and cost reduction. This study presents a novel approach for improving the quality of the steel manufacturing process and is expected to enhance overall efficiency in the steel manufacturing industry.

Towards an End-to-End Personal Fine-Tuning Framework for AI Value Alignment

This study introduces a novel architecture for value, preference, and boundary alignment in large language models (LLMs) and generative AI systems, accompanied by an experimental implementation. It addresses the limitations in AI model trustworthiness stemming from insufficient comprehension of personal context, preferences, and cultural diversity, which can lead to biases and safety risks. Using an inductive, qualitative research approach, we propose a framework for personalizing AI models to improve model alignment through additional context and boundaries set by users. Our framework incorporates user-friendly tools for identification, annotation, and simulation across diverse contexts, utilizing prompt-driven semantic segmentation and automatic labeling. It aims to streamline scenario generation and personalization processes while providing accessible annotation tools. The study examines various components of this framework, including user interfaces, underlying tools, and system mechanics. We present a pilot study that demonstrates the framework’s ability to reduce the complexity of value elicitation and personalization in LLMs. Our experimental setup involves a prototype implementation of key framework modules, including a value elicitation interface and a fine-tuning mechanism for language models. The primary goal is to create a token-based system that allows users to easily impart their values and preferences to AI systems, enhancing model personalization and alignment. This research contributes to the democratization of AI model fine-tuning and dataset generation, advancing efforts in AI value alignment. By focusing on practical implementation and user interaction, our study bridges the gap between theoretical alignment approaches and real-world applications in AI systems.

Automatic rib segmentation and sequential labeling via multi-axial slicing and 3D reconstruction

Automatic rib segmentation and sequential labeling via multi-axial slicing and 3D reconstruction

Cross-site Validation of AI Segmentation and Harmonization in Breast MRI.

This work aims to perform a cross-site validation of automated segmentation for breast cancers in MRI and to compare the performance to radiologists. A three-dimensional (3D) U-Net was trained to segment cancers in dynamic contrast-enhanced axial MRIs using a large dataset from Site 1 (n = 15,266; 449 malignant and 14,817 benign). Performance was validated on site-specific test data from this and two additional sites, and common publicly available testing data. Four radiologists from each of the three clinical sites provided two-dimensional (2D) segmentations as ground truth. Segmentation performance did not differ between the network and radiologists on the test data from Sites 1 and 2 or the common public data (median Dice score Site 1, network 0.86 vs. radiologist 0.85, n = 114; Site 2, 0.91 vs. 0.91, n = 50; common: 0.93 vs. 0.90). For Site 3, an affine input layer was fine-tuned using segmentation labels, resulting in comparable performance between the network and radiologist (0.88 vs. 0.89, n = 42). Radiologist performance differed on the common test data, and the network numerically outperformed 11 of the 12 radiologists (median Dice: 0.85-0.94, n = 20). In conclusion, a deep network with a novel supervised harmonization technique matches radiologists' performance in MRI tumor segmentation across clinical sites. We make code and weights publicly available to promote reproducible AI in radiology.

Global–Local Query-Support Cross-Attention for Few-Shot Semantic Segmentation

Few-shot semantic segmentation (FSS) models aim to segment unseen target objects in a query image with scarce annotated support samples. This challenging task requires an effective utilization of support information contained in the limited support set. However, the majority of existing FSS methods either compressed support features into several prototype vectors or constructed pixel-wise support-query correlations to guide the segmentation, which failed in effectively utilizing the support information from the global–local perspective. In this paper, we propose Global–Local Query-Support Cross-Attention (GLQSCA), where both global semantics and local details are exploited. Implemented with multi-head attention in a transformer architecture, GLQSCA treats every query pixel as a token, aggregates the segmentation label from the support mask values (weighted by the similarities with all foreground prototypes (global information)), and supports pixels (local information). Experiments show that our GLQSCA significantly surpasses state-of-the-art methods on the standard FSS benchmarks PASCAL-5i and COCO-20i.

VesselBoost: A Python Toolbox for Small Blood Vessel Segmentation in Human Magnetic Resonance Angiography Data

Magnetic resonance angiography (MRA) performed at ultra-high magnetic field provides a unique opportunity to study the arteries of the living human brain at the mesoscopic level. From this, we can gain new insights into the brain’s blood supply and vascular disease affecting small vessels. However, for quantitative characterization and precise representation of human angioarchitecture to, for example, inform blood-flow simulations, detailed segmentations of the smallest vessels are required. Given the success of deep learning-based methods in many segmentation tasks, we explore their application to high-resolution MRA data and address the difficulty of obtaining large data sets of correctly and comprehensively labelled data. We introduce VesselBoost, a vessel segmentation toolbox, which utilizes deep learning and imperfect training labels for accurate vasculature segmentation. To enhance the segmentation models’ robustness and accuracy, VesselBoost employs an innovative data augmentation technique, which captures the resemblance of vascular structures across scales by zooming in or out on input image patches—virtually creating diverse scale vascular data. This approach enables detailed vascular segmentation and ensures the model’s ability to generalize across various scales of vascular structures.

Vehicle Ego-Trajectory Segmentation Using Guidance Cues

Computer vision has significantly influenced recent advancements in autonomous driving by providing cutting-edge solutions for various challenges, including object detection, semantic segmentation, and comprehensive scene understanding. One specific challenge is ego-vehicle trajectory segmentation, which involves learning the vehicle’s path and describing it with a segmentation map. This can play an important role in both autonomous driving and advanced driver assistance systems, as it enhances the accuracy of perceiving and forecasting the vehicle’s movements across different driving scenarios. In this work, we propose a deep learning approach for ego-trajectory segmentation that leverages a state-of-the-art segmentation network augmented with guidance cues provided through various merging mechanisms. These mechanisms are designed to direct the vehicle’s path as intended, utilizing training data obtained with a self-supervised approach. Our results demonstrate the feasibility of using self-supervised labels for ego-trajectory segmentation and embedding directional intentions within the network’s decisions through image and guidance input concatenation, feature concatenation, or cross-attention between pixel features and various types of guidance cues. We also analyze the effectiveness of our approach in constraining the segmentation outputs and prove that our proposed improvements bring major boosts in the segmentation metrics, increasing IoU by more than 12% and 5% compared with our two baseline models. This work paves the way for further exploration into ego-trajectory segmentation methods aimed at better predicting the behavior of autonomous vehicles.

Enhancing Chinese–Braille translation: A two-part approach with token prediction and segmentation labeling

Visually assistive systems for the visually impaired play a pivotal role in enhancing the quality of life for the visually impaired. Assistive technologies for the visually impaired have undergone a remarkable transformation with the advent of deep learning and sophisticated assistive devices. In particular, the paper utilizes the latest machine translation models and techniques to accomplish the Chinese–Braille translation task, providing convenience for visually impaired individuals. The Traditional end-to-end Chinese–Braille translation approach incorporates Braille dots and Braille word segmentation symbols as tokens within the model’s vocabulary. However, our findings reveal that Braille word segmentation is significantly more complex than Braille dot prediction. The paper proposes a novel Two-Part Loss (TPL) method that treats these tasks distinctly, leading to significant accuracy improvements. To enhance translation performance further, we introduce a BERT-Enhanced Segmentation Transformer (BEST) method. BEST leverages knowledge distillation techniques to transfer knowledge from a pre-trained BERT model to the translate model, mitigating its limitations in word segmentation. Additionally, soft label distillation is employed to improve overall efficacy further. The TPL approach achieves an average BLEU score improvement of 1.16 and 5.42 for Transformer and GPT models on four datasets, respectively. In addition, The work presents a two-stage deep learning-based translation approach that outperforms traditional multi-step and end-to-end methods. The proposed two-stage translation method achieves an average BLEU score improvement of 0.85 across four datasets.

Improving image-based weld defects detection under interference information via a novel semantic supervision strategy

ABSTRACT Weld defects of skin-skeleton structures are invisible and image-based visual inspections using deep learning neural networks are in demand. The main limitation of previous detection algorithms is interference information in images. The reflective light and uneven brightness distribution hinder algorithms to achieve higher detection reliability. In this work, a novel supervision strategy for defects detection algorithms was proposed to break the limitation. A new semantic gate convolution block was developed to help the neural networks to distinguish between targets and interference. The block utilised semantic segmentation labels and a gate function to control the information transmitted to the detection output. Additionally, a new category-pixel-accuracy loss function was adopted to improve the effectiveness of semantic features. The new function reduced the effects of negative pixels to avoid over emphasis on semantic completeness, thus the ineffective features of interference could be eliminated. The results indicated that the back-propagated gradients from the supervision part taught the backbone networks to focus on correct objects instead of interference. To testify the validity of the current method, the algorithms was verified in burns and collapse defects. The detection accuracy under the new semantic supervision reached 99.1%, which was superior to common CNN.

Deep learning for automated boundary detection and segmentation in organ donation photography

Abstract Objectives Medical photography is ubiquitous and plays an increasingly important role in the fields of medicine and surgery. Any assessment of these photographs by computer vision algorithms requires first that the area of interest can accurately be delineated from the background. We aimed to develop deep learning segmentation models for kidney and liver organ donation photographs where accurate automated segmentation has not yet been described. Methods Two novel deep learning models (Detectron2 and YoloV8) were developed using transfer learning and compared against existing tools for background removal (macBGRemoval, remBGisnet, remBGu2net). Anonymised photograph datasets comprised training/internal validation sets (821 kidney and 400 liver images) and external validation sets (203 kidney and 208 liver images). Each image had two segmentation labels: whole organ and clear view (parenchyma only). Intersection over Union (IoU) was the primary outcome, as the recommended metric for assessing segmentation performance. Results In whole kidney segmentation, Detectron2 and YoloV8 outperformed other models with internal validation IoU of 0.93 and 0.94, and external validation IoU of 0.92 and 0.94, respectively. Other methods – macBGRemoval, remBGisnet and remBGu2net – scored lower, with highest internal validation IoU at 0.54 and external validation at 0.59. Similar results were observed in liver segmentation, where Detectron2 and YoloV8 both showed internal validation IoU of 0.97 and external validation of 0.92 and 0.91, respectively. The other models showed a maximum internal validation and external validation IoU of 0.89 and 0.59 respectively. All image segmentation tasks with Detectron2 and YoloV8 completed within 0.13–1.5 s per image. Conclusions Accurate, rapid and automated image segmentation in the context of surgical photography is possible with open-source deep-learning software. These outperform existing methods and could impact the field of surgery, enabling similar advancements seen in other areas of medical computer vision.

Change point detection via Gaussian mixture model

Change point detection aims to find abrupt changes in time series data. These changes denote substantial modifications to the process; these can be modeled as a change in the distribution (in location, scale, or trend). Traditional changepoint detection methods often rely on a cost function to assess if a change occurred in a series. Here, change point detection is investigated in a mixture-model-based clustering framework and a novel change point detection algorithm is developed using a finite mixture of regressions with concomitant variables. Through the introduction of a label correction mechanism, the unstructured clustering-based labels are treated as ordered and distinct segment labels. This approach can detect change points in both univariate and multivariate time series, and different kinds of change can be captured using a parsimonious family of models. Performance is illustrated on both simulated and real data. Journal of Statistical Research 2024, Vol. 58, No. 1, pp. 197-219.

GKE-TUNet: Geometry-Knowledge Embedded TransUNet Model for Retinal Vessel Segmentation Considering Anatomical Topology.

Automated retinal vessel segmentation is crucial for computer-aided clinical diagnosis and retinopathy screening. However, deep learning faces challenges in extracting complex intertwined structures and subtle small vessels from densely vascularized regions. To address these issues, we propose a novel segmentation model, called Geometry-Knowledge Embedded TransUNet (GKE-TUNet), which incorporates explicit embedding of topological features of retinal vessel anatomy. In the proposed GKE-TUNet model, a skeleton extraction network is pre-trained to extract the anatomical topology of retinal vessels from refined segmentation labels. During vessel segmentation, the dense skeleton graph is sampled as a graph of key-points and connections and is incorporated into the skip connection layer of TransUNet. The graph vertices are used as node features and correspond to positions in the low-level feature maps. The graph attention network (GAT) is used as the graph convolution backbone network to capture the shape semantics of vessels and the interaction of key locations along the topological direction. Finally, the node features obtained by graph convolution are read out as a sparse feature map based on their corresponding spatial coordinates. To address the problem of sparse feature maps, we employ convolution operators to fuse sparse feature maps with low-level dense feature maps. This fusion is weighted and connected to deep feature maps. Experimental results on the DRIVE, CHASE-DB1, and STARE datasets demonstrate the competitiveness of our proposed method compared to existing ones.

PatchNet: Maximize the Exploration of Congeneric Semantics for Weakly Supervised Semantic Segmentation.

With the increase in the number of image data and the lack of corresponding labels, weakly supervised learning has drawn a lot of attention recently in computer vision tasks, especially in the fine-grained semantic segmentation problem. To alleviate human efforts from expensive pixel-by-pixel annotations, our method focuses on weakly supervised semantic segmentation (WSSS) with image-level labels, which are much easier to obtain. As a considerable gap exists between pixel-level segmentation and image-level labels, how to reflect the image-level semantic information on each pixel is an important question. To explore the congeneric semantic regions from the same class to the maximum, we construct the patch-level semantic augmentation network (PatchNet) based on the self-detected patches from different images that contain the same class labels. Patches can frame the objects as much as possible and include as little background as possible. The patch-level semantic augmentation network that is established with patches as the nodes can maximize the mutual learning of similar objects. We regard the embedding vectors of patches as nodes and use a transformer-based complementary learning module to construct weighted edges according to the embedding similarity between different nodes. Moreover, to better supplement semantic information, we propose softcomplementary loss functions matched with the whole network structure. We conduct experiments on the popular PASCAL VOC 2012 and MS COCO 2014 benchmarks, and our model yields the state-of-the-art performance.

A deep learning framework for predicting endometrial cancer from cytopathologic images with different staining styles.

Endometrial cancer screening is crucial for clinical treatment. Currently, cytopathologists analyze cytopathology images is considered a popular screening method, but manual diagnosis is time-consuming and laborious. Deep learning can provide objective guidance efficiency. But endometrial cytopathology images often come from different medical centers with different staining styles. It decreases the generalization ability of deep learning models in cytopathology images analysis, leading to poor performance. This study presents a robust automated screening framework for endometrial cancer that can be applied to cytopathology images with different staining styles, and provide an objective diagnostic reference for cytopathologists, thus contributing to clinical treatment. We collected and built the XJTU-EC dataset, the first cytopathology dataset that includes segmentation and classification labels. And we propose an efficient two-stage framework for adapting different staining style images, and screening endometrial cancer at the cellular level. Specifically, in the first stage, a novel CM-UNet is utilized to segment cell clumps, with a channel attention (CA) module and a multi-level semantic supervision (MSS) module. It can ignore staining variance and focus on extracting semantic information for segmentation. In the second stage, we propose a robust and effective classification algorithm based on contrastive learning, ECRNet. By momentum-based updating and adding labeled memory banks, it can reduce most of the false negative results. On the XJTU-EC dataset, CM-UNet achieves an excellent segmentation performance, and ECRNet obtains an accuracy of 98.50%, a precision of 99.32% and a sensitivity of 97.67% on the test set, which outperforms other competitive classical models. Our method robustly predicts endometrial cancer on cytopathologic images with different staining styles, which will further advance research in endometrial cancer screening and provide early diagnosis for patients. The code will be available on GitHub.

CC-SMC: Chain coding-based segmentation map lossless compression

A segmentation map, either static or dynamic, refers to a two-dimensional picture that may vary with time and indicates the segmentation label per pixel. Both the semantic map and the occupancy map in video-based point cloud compression (V-PCC) belong to the segmentation map we referred to. The semantic map can work for many machine vision tasks like tracking and has been used as a layer of image representation in some image compression methods. The occupancy map constitutes a part of the point cloud coding bitstream. Since segmentation maps are widely used, how to efficiently compress them is of interest. We propose a segmentation map lossless compression scheme namely CC-SMC, exploiting the nature of segmentation maps that usually contain limited colors and sharp edges. Specifically, we design a chain coding-based scheme combined with quadtree-based block partitioning. For intraframe coding, one block is partitioned recursively with a quadtree structure, until the block contains only one color, is smaller than a threshold, or satisfies the defined chain coding condition. We revise the three-orthogonal chain coding method to incorporate contextual information and design effective intraframe prediction methods. For interframe coding, one block may find a reference block; the chain difference between the current and the reference blocks is coded. We implement the proposed scheme and test it on several different kinds of segmentation maps. Compared with advanced lossless image compression techniques, our proposed scheme obtains more than 10% bits reduction as well as more than 20% decoding time-saving. The code is available at https://github.com/Yang-Runyu/CC-SMC.

Video Coding for Machines: Compact Visual Representation Compression for Intelligent Collaborative Analytics.

As an emerging research practice leveraging recent advanced AI techniques, e.g. deep models based prediction and generation, Video Coding for Machines (VCM) is committed to bridging to an extent separate research tracks of video/image compression and feature compression, and attempts to optimize compactness and efficiency jointly from a unified perspective of high accuracy machine vision and full fidelity human vision. With the rapid advances of deep feature representation and visual data compression in mind, in this paper, we summarize VCM methodology and philosophy based on existing academia and industrial efforts. The development of VCM follows a general rate-distortion optimization, and the categorization of key modules or techniques is established including feature-assisted coding, scalable coding, intermediate feature compression/optimization, and machine vision targeted codec, from broader perspectives of vision tasks, analytics resources, etc. From previous works, it is demonstrated that, although existing works attempt to reveal the nature of scalable representation in bits when dealing with machine and human vision tasks, there remains a rare study in the generality of low bit rate representation, and accordingly how to support a variety of visual analytic tasks. Therefore, we investigate a novel visual information compression for the analytics taxonomy problem to strengthen the capability of compact visual representations extracted from multiple tasks for visual analytics. A new perspective of task relationships versus compression is revisited. By keeping in mind the transferability among different machine vision tasks (e.g. high-level semantic and mid-level geometry-related), we aim to support multiple tasks jointly at low bit rates. In particular, to narrow the dimensionality gap between neural network generated features extracted from pixels and a variety of machine vision features/labels (e.g. scene class, segmentation labels), a codebook hyperprior is designed to compress the neural network-generated features. As demonstrated in our experiments, this new hyperprior model is expected to improve feature compression efficiency by estimating the signal entropy more accurately, which enables further investigation of the granularity of abstracting compact features among different tasks.

Assessing CT-based Volumetric Analysis via Transfer Learning with MRI and Manual Labels for Idiopathic Normal Pressure Hydrocephalus.

Brain computed tomography (CT) is an accessible and commonly utilized technique for assessing brain structure. In cases of idiopathic normal pressure hydrocephalus (iNPH), the presence of ventriculomegaly is often neuroradiologically evaluated by visual rating and manually measuring each image. Previously, we have developed and tested a deep-learning-model that utilizes transfer learning from magnetic resonance imaging (MRI) for CT-based intracranial tissue segmentation. Accordingly, herein we aimed to enhance the segmentation of ventricular cerebrospinal fluid (VCSF) in brain CT scans and assess the performance of automated brain CT volumetrics in iNPH patient diagnostics. The development of the model used a two-stage approach. Initially, a 2D U-Net model was trained to predict VCSF segmentations from CT scans, using paired MR-VCSF labels from healthy controls. This model was subsequently refined by incorporating manually segmented lateral CT-VCSF labels from iNPH patients, building on the features learned from the initial U-Net model. The training dataset included 734 CT datasets from healthy controls paired with T1-weighted MRI scans from the Gothenburg H70 Birth Cohort Studies and 62 CT scans from iNPH patients at Uppsala University Hospital. To validate the model's performance across diverse patient populations, external clinical images including scans of 11 iNPH patients from the Universitatsmedizin Rostock, Germany, and 30 iNPH patients from the University of Alabama at Birmingham, United States were used. Further, we obtained three CT-based volumetric measures (CTVMs) related to iNPH. Our analyses demonstrated strong volumetric correlations (ϱ=0.91, p<0.001) between automatically and manually derived CT-VCSF measurements in iNPH patients. The CTVMs exhibited high accuracy in differentiating iNPH patients from controls in external clinical datasets with an AUC of 0.97 and in the Uppsala University Hospital datasets with an AUC of 0.99. CTVMs derived through deep learning, show potential for assessing and quantifying morphological features in hydrocephalus. Critically, these measures performed comparably to gold-standard neuroradiology assessments in distinguishing iNPH from healthy controls, even in the presence of intraventricular shunt catheters. Accordingly, such an approach may serve to improve the radiological evaluation of iNPH diagnosis/monitoring (i.e., treatment responses). Since CT is much more widely available than MRI, our results have considerable clinical impact.