Sediments in the upper Yangtze River have significantly changed over the past 60 years. The characteristics and causes of these sediment changes must be determined in the upcoming phases of the comprehensive management of the Yangtze River Basin. Based on sediment observation data from 1960 to 2020, this study examined the trends and sudden changes in the sediments in the mainstream and its significant tributaries in the upper Yangtze River. The relative contributions of precipitation change and various human activities to sediment load changes are quantified. The relationships between sediment variations and the construction and large dam projects, soil and water conservation measures, and earthquake disasters are established. The results indicate that there was a significant decline in sediment load with main changes occurring around the 1985s and 2010s. Multiple double mass curves are used to quantify the relative contributions of precipitation change and human activities to sediment load changes. The relative contribution of dams to the decrease in sediment load ranges from 53 % to 74 %. Precipitation change serves a significant role in the observed changes, accounting for a range of 10 % to 27 %. Soil conservation measures take some time to show their impact on sediment reduction. These measures work by stabilizing the soil and improving hydrological conditions. On average, they contribute between 7 % and 20 % towards reducing sediment. In recent times, there has been a noticeable rise in sediment load in rivers like the Jialing and Min Rivers. This unexpected increase could potentially be linked to a combination of factors including earthquakes, heavy precipitation, and localized sediment scouring. The results of this study offer valuable insights into the variations in river sediment load, aiding in the improved management of water resources and sediment in large dams. These findings provide helpful insights for dam management.