Sedentary Research Articles

Comparative Analysis of Adherence to 24-Hour Movement Guidelines in Adolescents: Objective vs. Subjective Measures

Background and AimsPrevious studies have investigated the concordance between objective and subjective measures for assessing physical activity, sedentary behaviour, and sleep duration separately. However, no studies have compared adherence to the 24-hour movement guidelines using both objective and subjective measures in adolescents. The aim of this study was to compare adherence to the 24-hour movement guidelines using both objective and subjective measures MethodsA comprehensive search was conducted in PubMed, Scopus, Web of Science, EMBASE, CINAHL, and SPORTDiscus up to May 2024. A meta-analysis using a random-effects model was conducted, and a p-value of <0.05 was considered statistically significant. ResultsOf the 5,968 studies identified, only 42 met the inclusion criteria, with the included studies reporting a mean age of participants ranging from 11.99 to 17.99 years, comprising a total sample of 856,235 participants. There was no statistically significant difference between objective and self-reported measures of adherence to the 24-hour movement guidelines (p>0.05). When analysing each behaviour separately, there was a statistically significant difference between objective and self-reported measures of physical activity and sleep time (p<0.05). Regarding sedentary behaviour, all studies used subjective measures; therefore, no meta-analysis was performed for screen time as all studies relied on subjective measures. ConclusionBased on these findings, both objective and subjective measures can be used to assess adherence to the 24-hour movement guidelines in adolescents. Thus, researchers and policymakers can choose either objective or subjective methods to assess adherence to the 24-hour movement guidelines, with decisions tailored to the clinical context.

Impact of Replacing Sedentary Behavior with Physical Activity and Sleep on Stroke Risk: A Prospective Cohort Study.

Our research explores how leisure-time sedentary behavior (SB) correlates with stroke risk. Additionally, we utilize the isotemporal substitution model (ISM) to examine how replacing brief durations of leisure-time SB with light physical activity (LPA), moderate physical activity (MPA), vigorous physical activity (VPA), and sleep might influence the risk of stroke. This investigation tracked 478,198 participants from the UK Biobank. Data regarding individual leisure-time SB and PA were collected through a standardized questionnaire. A Cox proportional hazards model, alongside an isotemporal substitution model (ISM), was utilized. We identified 10,003 cases of incident stroke over 12.7 years. When compared to participants who engaged in leisure-time SB for less than 4hours per day, the hazard ratios (HRs) for stroke incidence increased with more prolonged leisure-time SB: HRs were 1.06 (95% CI: 1.01 to 1.11) for 4-6h/d, 1.16 (95% CI: 1.10 to 1.23) for 6-8h/d, and 1.24 (95% CI: 1.15 to 1.33) for over 8h/d. According to the ISM analysis, substituting leisure-time SB with various forms of PA could markedly reduce stroke risk. For individuals sleeping ≤8h/d, replacing one hour of leisure-time SB with an equivalent duration of LPA, VPA, or sleep corresponded to a 3.0%, 7.0%, and 22.0% decrease in stroke risk, respectively. Meanwhile, for those already sleeping more than 8h/d, substituting one hour of leisure-time SB with an equivalent duration of LPA or VPA resulted in a notable decrease in the risk of stroke by 6.0% and 18.0%, respectively. The findings demonstrate that leisure-time SB and unhealthy sleep durations are confirmed risk factors for stroke. For individuals sleeping 8hours or less per day, and for those who sleep more than 8hours, substituting SB with an adequate amount of sleep or engaging in VPA, respectively, emerges as an effective strategy for reducing stroke risk.

Prevalence and Risk Factors Associated with Depressive Symptoms Among Healthcare Professionals at a Tertiary Care Hospital in Mogadishu, Somalia: A Cross-Sectional Study.

Depression, a prevalent mental health issue, can significantly impact healthcare workers (HCWs), leading to decreased productivity, increased turnover, and high medical errors. However, there is a dearth of information regarding depression among healthcare professionals in Somalia. Therefore, this study aimed to assess the magnitude and risk factors associated with depressive symptoms among healthcare professionals in Mogadishu, Somalia. A hospital-based cross-sectional study was conducted among HCWs at Erdogan Hospital, in the capital city of Somalia. Data was collected using questionnaires on socio demographic, work-related characteristics and Patient Health Questionnaire-9 (PHQ-9). Bivariate and multivariate logistic regression analyses were conducted to identify variables associated with depressive symptoms. A p-values of 0.05 as a cutoff for a significant association. The prevalence of depressive symptoms among healthcare professionals was 48.9% (95% CI: 45.4-56.9%). In multivariable analysis, being female (AOR = 2.05; 95% CI: 1.17-3.60), being a nurse (AOR = 3.11; 95% CI: 1.14-8.48), unmarried (AOR = 1.83; 95% CI: 1.04-3.21), having insufficient sleep (AOR = 2.61; 95% CI: 1.45-4.70), a family history of mental illness (AOR = 3.31; 95% CI: 1.49-7.36), lack of physical activity (AOR = 2.59; 95% CI: 1.19-5.62), and having low social support (AOR = 3.06; 95% CI: 1.17-7.98) were all associated with increased odds of experiencing depressive symptoms. The study showed that nearly half of healthcare professionals experienced depressive symptoms. The study underscores the importance of efficient screening methods for identifying psychological symptoms in healthcare professionals, which is essential for enhancing their mental health and patient care. Therefore, we recommend that healthcare institutions and policymakers develop and implement screening measures to identify and improve the mental health well-being of HCWs, as well as provide high-quality patient care.

Understanding the Complex Interplay of Epigenetic Factors in Atherosclerosis: A Review

This review focuses on the epigenetic factors that play a vital role in the formation of plaques and lead to atherosclerosis and related diseases in humans during current times. Apart from the epigenetics there are plenty more factors that influence the atherosclerotic risk in the older population of the current era. Lack of physical activities has become one of the most commonly found traits that causes obesity in people especially the middles aged adults. People working 9 - 5 in an office, or an IT firm tend spend idle time with their computer for 4 - 5 consecutive hours with barely changing their position. Lack of exercise tends to affect not only the physical health but also stress a person mentally. Chronic inflammatory diseases like atherosclerosis have a major role in the morbidity and mortality from cardiovascular disease worldwide. Atherosclerotic plaques are created by the pathophysiological process of lipids, inflammatory cells and fibrous components gradually accumulating within artery walls. Endothelial dysfunction signals the start of atherosclerosis and allows low-density lipoproteins (LDL) to enter the subendothelial region. Oxidative stress-induced changes in retained low-density lipoprotein (LDL) set off an inflammatory cascade that draws T cells and monocytes to the site of the lesion. The interaction of these immune cells with the local vascular cells encourages the production of foam cells, which fills the plaque’s centre with lipids. Smooth muscle cells multiply and help produce fibrous caps as the lesion ages, which affects the stability of the plaque. Studies shows how the brain responds to physical labour and how differently the effectively the enzymes and hormones are secreted, and their actions are vastly guided based on the physical stress an individual undergoes. Among the most prominent causes of atherosclerosis epigenetics has been focussed majorly in this review, where we focus on the underlying genetic factors that play a vital role in atherosclerosis and related cardiovascular diseases and also the genetic approach to a treatment is also elaborated. A number of miRNAs are involved in the cause/cure for the atherosclerosis, the following tables give an outlook regarding the same. This review aims to focus on the causes, risk factors, pathophysiology and the treatment and therapies that are currently available all the way concentrating on the genetic approach in the above-mentioned perspective. HIGHLIGHTS The review revolves around the modifiable and non-modifiable risk factors leading to atherosclerosis. Key risk factors and epigenetics causes of atherosclerosis and atherosclerosis related Cardio vascular Diseases (CVD). The article explains in detail regarding the pathophysiology of atherosclerosis. The progression and stages of atherosclerosis. GRAPHICAL ABSTRACT

Advanced ECG Monitoring: Machine Learning And Robotics For Real-Time Health Management

Cardiovascular diseases are becoming increasingly prevalent due to lifestyle factors such as poor diet, lack of exercise, and conditions like diabetes and hypertension. Electrocardiography (ECG) is a widely used diagnostic tool for detecting various heart conditions, including arrhythmias and myocardial infarction. However, manual analysis of ECG signals is often subjective, time-consuming, and prone to variability. To address these challenges, this paper proposes a comprehensive system that integrates an Arduino-based ECG acquisition module with neural networks for automatic analysis and a robotic system for autonomous sensor placement and intervention. The main objective is to create a smart, real-time ECG monitoring and Computer-Aided Diagnosis (CAD) system capable of early detection and management of heart diseases. The system utilizes machine learning and deep learning techniques to enhance diagnostic accuracy, focusing on implementing a neural network model for ECG classification. A robotic arm is also integrated into the system to ensure precise sensor placement and emergency response

Act now - serious pathology of the spine is affected by health inequalities

Early diagnosis of serious spinal pathology is the key to optimise patient outcomes, yet early diagnosis can be adversely affected by health inequalities. In this paper we consider the impact of health inequalities on the incidence and outcome for serious spinal musculoskeletal (MSK) pathologies. Health inequalities can be experienced by people grouped around a range of factors. These include socio-economic factors, the environmental conditions in which people live, protected characteristics such as ethnicity, and socially excluded groups such as people who are homeless. These factors can affect people’s exposure to health risks and their opportunities to lead healthy lives. A person’s behaviour is a key determinant of their health status. ‘Risky’ health behaviours include smoking, poor diet, harmful alcohol consumption and lack of exercise, and are more common in these groups. Importantly, socio-economic factors combined with health behaviours influence the health inequalities a person may experience. The most significant social and economic factors influencing poor MSK health are poverty, education, employment, environment, and food ethos. These determinants of health not only predispose people living in deprivation to having benign MSK conditions at a younger age and with worse outcomes, they are also risk factors of more serious MSK pathologies.

Analysis of the Effectiveness of a Fall Prevention Program Incorporating an Interprofessional Team Collaboration Model on Reducing Fall Risk in Elderly Living in Long-term Care Facilities

Concurrent with population ageing, falls have become a significantly more challenging public health issue among older adults. Three years of data collected recently from a nursing home in northern Taiwan reveals an increasing trend in fall density that is primarily associated with aging, physiological decline, chronic diseases, polypharmacy, osteoporosis, and lack of exercise. The percentage of nursing home residents at high risk of falls is currently at 12.6%, and the fall rate has been reported as reaching as high as 30% annually. A fall prevention program was implemented to reduce the fall incidence rate to 18%, with secondary goals of improving fall prevention awareness, behavior, self-efficacy, lower limb muscle strength, balance, and gait by 10% on average, respectively, between pre-test and post-test. From September 30, 2023 to February 29, 2024, a health promotion activity and fall prevention exercise course were implemented using an interdisciplinary team collaboration model over a six-week period, providing individualized exercise for the participants. The study included 20 older adults with an average age of 88 years. Most (90%; n = 18) had chronic diseases, 25% (n = 5) were on more than nine medications, 70% (n = 14) had reduced bone mass, and 40% (n = 8) were at high risk of falls, with a fall incidence rate of 30% during the immediately preceding year. Post-intervention, the fall incidence rate dropped to 5%, fall prevention awareness, behavior, and self-efficacy increased by 18.3%, and lower limb muscle strength, balance, and gait improved by 11.7%. The post-test results in fall prevention awareness, behavioral changes, self-efficacy, and lower limb strength, balance, and gait were all significantly better than pre-test results, with all results achieving statistical significance. The project results support the positive effects of the developed intervention effectively on elderly physical fitness and fall risk, providing valuable insights for the implementation of fall prevention strategies in nursing homes.

Examining the multifaceted factors of night eating syndrome among adults in Saudi Arabia: A nursing perspective

BackgroundNight Eating Syndrome (NES) is a prevalent eating disorder that significantly impacts individuals' quality of life and well-being. However, most NES research has focused on adolescent populations, leaving a significant gap in our understanding of its prevalence and predictors among adults, particularly in the MENA region. This study, therefore, presents a novel contribution by filling this gap and determining the prevalence of NES and its predictors among adults in Abha, Saudi Arabia. DesignA descriptive correctional design was conducted on 714 adults randomly recruited from primary healthcare centers (PHCCs). MethodsA self-administered questionnaire, which comprised a demographic and lifestyle data sheet and the Arabic version of the NES questionnaire, was used for data collection. Results13.3 % of the participants reported having full syndrome of NES, with 16.1 % of males and 22.5 % of females reporting high NES awareness. Meanwhile, 14.4 % of the participants were non-emotional eaters. This finding is significant as it sheds light on the high prevalence of NES among Saudi adults. Significant differences were observed between NES and higher education, sleeping patterns, smoking habits, dietary type, and exercise routines, with an OR of 1.422, 40.78, 6.14, 66.70, and 4.47, respectively, and a p-value of <0.001. ConclusionNES was a common eating disorder among Saudi adults. Higher education, inadequate sleep, smoking, unhealthy diet, and lack of exercise were the most significant predictors of NES. These findings underline the importance of addressing these factors in preventing and managing NES. Social media campaigns, awareness campaigns, and cognitive behavioral and mindfulness therapies could effectively address NES. However, further research is necessary to identify underlying causes and assess their association with comorbidities, providing a clear direction for future studies.

Effects of deep-sea water on training efficiency, locomotor function and respiratory metabolism in young and aged mice

Deep sea water (DSW) contains many trace minerals, and its applications, which include its use as drinking water, have gradually been expanding. Generally, humans tend to be lacking in mineral intake and deficiencies of trace minerals may increase the risk of several health problems. In recent years, the lack of exercise among the elderly has become an issue, leading to the onset of frailty and sarcopenia, which in turn increases the risk of dementia. Therefore, we investigated whether the daily intake of DSW-extract-added water (DSW; hardness 300 mg/L) impacted the training effect in aged mice. Treatment with DSW significantly induced a training effect in aged mice subjected to treadmill exercise. Locomotor function and metabolic capacity were also significantly increased in aged mice after DSW treatment. The results indicate that daily intake of DSW may enhance the training effect of exercise and affect locomotor performance.

Co-creation and evaluation of an algorithm for the development of a mobile application for wound care among new graduate nurses: A mixed methods study.

Chronic wounds are a growing concern due to aging populations, sedentary lifestyles and increasing rates of obesity and chronic diseases. The impact of such wounds is felt worldwide, posing a considerable clinical, environmental and socioeconomic challenge and impacting the quality of life. The increasing complexity of care requires a holistic approach, along with extensive knowledge and skills. The challenge experienced by health-care professionals is particularly significant for newly graduate nurses, who face a gap between theory and practice. Digital tools, such as mobile applications, can support wound care by facilitating more precise assessments, early treatment, complication prevention and better outcomes. They also aid in clinical decision-making and improve healthcare delivery in remote areas. Several mobile applications have emerged to enhance wound care. However, there are no applications dedicated to newly graduate nurses. The aim of this study was to co-create and evaluate an algorithm for the development of a wound care mobile application supporting clinical decisions for new graduate nurses. The development of this mobile application is envisioned to improve knowledge application and facilitate evidence-based practice. This study is part of a multiphase project that adopted a pragmatic epistemological approach, using the 'Knowledge-to-Action' conceptual model and Duchscher's Stages of Transition Theory. Following a scoping review, an expert consensus, and stakeholder meetings, this study was pursued through a sequential exploratory mixed methods design carried out in two phases. In the initial phase, 21 participants engaged in semi-structured focus groups to explore their needs regarding clinical decision support in wound care, explore their perceptions of the future mobile application's content and identify and categorize essential components. Through descriptive analysis, five overarching themes emerged, serving as guiding principles for conceptual data model development and refinement. These findings confirmed the significance of integrating a comprehensive glossary complemented by photos, ensuring compatibility between the mobile application and existing documentation systems, and providing quick access to information to avoid burdening work routines. Subsequently, the algorithm was created from the qualitative data collected. The second phase involved presenting an online SurveyMonkey® questionnaire to 34 participants who were not part of the initial phase to quantitatively measure the usability of this algorithm among future users. This phase revealed very positive feedback regarding the usability [score of 6.33 (±0.19) on a scale of 1-7], which reinforces its quality. The technology maturation process can now continue with the development of a prototype and subsequent validation in a laboratory setting.

Review of current and new drugs for the treatment of metabolic-associated fatty liver disease.

In the past 3 decades, metabolic-associated fatty liver disease (MAFLD) has emerged as a widespread liver condition, with its global prevalence on the rise. It ranks as a leading contributor to hepatocellular carcinoma (HCC) and necessitates liver transplantation. Under the multiple parallel hits model, the pathogenesis of MAFLD stems from various liver stressors, notably nutrient overload and sedentary lifestyles. While medical management for MAFLD is well-established, encompassing non-pharmaceutical and pharmaceutical interventions, determining the most effective pharmaceutical therapy has remained elusive. This review discusses diabetic medications for MAFLD treatment, emphasizing recent studies and emerging drugs while reviewing other nondiabetic agents. Emerging evidence suggests that combination therapies hold promise for resolving MAFLD and metabolic steatohepatitis (MASH) while managing side effects. Ongoing trials play a pivotal role in elucidating the effects of mono, dual, and triple receptor agonists in individuals with MASH. With the rising burden of MAFLD/MASH and its severe consequences, the need for effective treatments is more pressing than ever. This review provides a comprehensive overview of the current landscape of pharmaceutical interventions for MAFLD and MASH, shedding light on the potential of newer drugs especially diabetic medications and the importance of ongoing research in this field.

Surface electromyographic analysis of the bilateral abdomen and back muscle during selected yoga posture

Sedentary lifestyles lead to postural deformities, Lower Back Pain(LBP) and Colorectal cancer(CRC). Practicing Yoga attains definite strength in muscles by activating muscle fibers. The Yoga poses analyzed are often used in strengthening and stability programs for the abdomen and back muscles. ObjectiveTo determine the potential use of Dolphin pose and Dolphin plank in specific strengthening endurance and rehabilitation programs via sEMG analysis in the selected bilateral abdomen and lower back muscles. MethodsSurface electromyographic analysis was conducted on bilateral muscles, including the Rectus Abdominis(RA), External oblique(EO), Internal oblique(IO), and Erector Spinae(ES), resulting in Dolphin pose(DS), Dolphin plank(DP), and High plank(HP). Data were expressed by Root Mean Square(RMS) of each bilateral muscle during each Pose normalized as 100% of maximum voluntary isometric contraction(MVIC). ResultsDolphin plank(DP) generated a very high-level muscle activation than 100% MVIC in all bilateral muscles, and there was a significant main effect of Pose e (p < 0.001). Erector spinae generated more activation in the Dolphin pose (p < 0.05) than in the HP and DS. No significant difference between bilateral activity differences in DP and DS. There was a significant difference between RRA and LRA (p < 0.001) and RIO and LIO (p < 0.0001). ConclusionFindings have suggested that the Dolphin plank could be used for abdomen strengthening, performance enhancement, and rehabilitation programs. Dolphin pose may benefit lower back stability by providing endurance to the Erector spinae muscle. So, this yoga pose can be incorporated into the yoga training module for addressing lower back pain(LBP) caused by longer sitting in a sedentary lifestyle.

Screening the carotenoid in vitro bioaccessibility of purple corn breakfast cereal consumed with milk and plant-based milk

Chronic non-communicable diseases (NCDs), such as cardiovascular diseases, diabetes, and cancer, dominate global mortality, besides compromising the quality of life. Unhealthy habits like sedentary lifestyles and poor diets escalate NCD risks. Conversely, the consumption of phenolic compounds and carotenoids has shown promise in reducing NCD risks. The food industry responds by adapting products to meet demands for healthier options rich in bioactive compounds. For instance, breakfast cereals made from purple and yellow corn offer carotenoids and anthocyanins and form a nutrient-balanced meal when consumed with milk or alternatives. However, bioactive compounds in food do not guarantee absorption, necessitating bioaccessibility studies. In this study, we aimed to evaluate the bioaccessibility of the major carotenoids in two breakfast cereals, one made with 100 % yellow corn and the other with 50 % purple corn, co-digested with whole milk, semi-skimmed milk, skimmed milk, and almond “milk”. The bioaccessibility of lutein in the breakfast cereals was evaluated using the INFOGEST 2.0 in vitro digestion method. Results showed that lutein bioaccessibility ranged from 9 % to 29 %. The bioaccessibility was lower than that observed in other food matrices, such as spinach and maize products. High fiber, low carotenoid contents, and anthocyanin presence negatively influenced the carotenoid bioaccessibility. Interestingly, the varying lipid content of milk showed no impact on lutein bioaccessibility under the examined conditions. In conclusion, the effects of lipids in a low range (0–7 %) are not significant (p > 0.05) compared to other matrix components. When developing new products with health and nutritional benefits, it is important to consider that while fiber can reduce the bioaccessibility of carotenoids, it remains crucial for gut health.

Moderate physical activity and higher frequency are inversely associated with incidence of frailty in middle-aged and older population: a 4-year longitudinal study in Europe.

Global aging is leading to an increase in frailty patients, and physical activity (PA) may have an impact on frail in middle-aged and older population. This study aimed to explore the relationship between the frequency of different PA intensities and the incidence and prevalence of frailty in middle-aged and older adults based on the Survey of Health, Ageing, and Retirement in Europe (SHARE). Self-reported questionnaires were used to obtain information on demographics and PA, and frailty was assessed using the SHARE Frailty Instrument (SHARE-FI). Cox regression and logistic regression models were used to explore the association between PA and frailty and stratified according to middle or old age. Among 6315 baseline non-frail participants aged 44-96years, 16.1% developed frailty over 4years, with higher incidence and prevalence in women (P < 0.05). Women accounting for 55.80% of the sample. The frequency of participants participating in sports decreased over 4years (P < 0.05). Compared with participants who engaged in PA more than once a week, participants who engaged in moderated PA less frequently had a higher risk of new-onset frailty (HR: 3.174-6.115), and participants who engaged in vigorous PA 1-3 times a month had a higher risk of new-onset frailty (HR: 1.335). Participation in low-frequency moderate PA and vigorous PA 1-3 times per month were positively associated with the prevalence of frailty (P < 0.05). Physical activity frequency decreases with age in middle-aged and older adults. Those adults who engage in moderate PA more than once a week have a lower risk of incidence of frailty, compared to those with more sedentary life-styles. Additionally, women need to pay more attention to frailty management.

Behavioral patterns in elderly single-person households

The global rise in the aging population and the increase in older adults living alone have raised concerns about health-related behaviors, particularly sedentary lifestyles and reduced daily activities. These behaviors are linked to higher risks of physical and cognitive conditions. While many global studies have explored these patterns, research within the Chilean context remains limited. This work presents a analysis of behavioral patterns in elderly individuals living alone in Chile, offering valuable insights into this population. Using clustering techniques, we identified two distinct activity patterns among the participants. The first pattern is characterized by a gradual increase in activity during the day, peaking around midday and followed by a decline, likely associated with meal preparation and rest. The second pattern demonstrates a more dynamic lifestyle, with a rapid surge in activity after waking and sustained levels throughout the day, suggesting a potentially healthier approach to aging. These findings align with previous studies indicating high levels of sedentary behavior in older adults, reinforcing the need for interventions tailored to diversify daily routines and promote physical activity. This study is the first to explore these patterns in the Chilean context, contributing to a more comprehensive understanding of elderly care and informing future strategies for improving the well-being of older adults living alone.

Analysis of the global burden of CKD-T2DM in young and middle-aged adults in 204 countries and territories from 2000 to 2019: A systematic study of the global burden of disease in 2019

BackgroundDiabetes stands as a principal risk factor for severe complications including renal and cardiovascular diseases. The gradual rise in type 2 diabetes cases globally, coupled with a trend towards younger demographics, has led to an escalating prevalence of chronic kidney disease. However, its etiology is multifaceted, necessitating individualized treatment and refinement, particularly crucial in screening and managing the burden of CKD-T2DM. A comprehensive analysis of CKD-T2DM burden at global, regional, and national levels from 2000 to 2019, based on the latest data, can inform screening, early diagnostics, and treatment strategies, thereby optimizing healthcare resource allocation. MethodsUtilizing data sourced from the Global Burden of Disease (GBD) database, we delineated the incidence, mortality, and DALYs rates of CKD-T2DM from 2000 to 2019 across global, regional, and national scales. We summarized the age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized death rate (ASDR) of CKD-T2DM globally, regionally, and nationally, presenting them visually. Moreover, we calculated and visually depicted the estimated annual percentage change (EAPC) of various CKD-T2DM indicators at these levels. Additionally, CKD-T2DM patients were stratified by age to compare the age distribution of patient deaths and the age burden between 2000 and 2019. FindingsThe disease burden of CKD-T2DM among young and middle-aged individuals globally has shown a sustained increase from 2000 to 2019. Incidence, mortality, and DALYs rates have exhibited an overall upward trend, with males showing higher rates compared to females. Significant disparities exist among different countries and regions, with India, China, and Mexico emerging as the countries with the highest number of new cases. Nicaragua, Mexico, and the United Arab Emirates have the highest age-standardized incidence rates, whereas Uganda, Ethiopia, and Burundi have the lowest. At the age level, the burden of CKD-T2DM exhibits varying trends among different age groups but generally shows an upward trajectory, particularly in the 45–49 age bracket. High systolic blood pressure and high BMI stand as the primary contributing factors to mortality and DALYs, with variations in their influence observed across different regions and levels of development. Interpretationver the past 20 years, the burden of CKD-T2DM among young and middle-aged individuals globally has continued to increase, with disparities existing among different countries, regions, and age groups, but overall showing an upward trend. The reasons for this trend are multifaceted, including global lifestyle changes such as dietary shifts, sedentary lifestyles, obesity, as well as population aging and inadequate preventive measures in certain regions. Addressing these challenges necessitates optimizing screening methods, adjusting lifestyles, enhancing management strategies, improving medical care and awareness levels, particularly intensifying awareness and screening efforts among males, reinforcing prevention and control measures for the 45–49 age group, enhancing infrastructure and healthcare resources in developing countries, fostering international collaboration, and implementing context-specific measures.

Prognostic Influence of Physical Activity and Sedentary Behavior in Patients with CKD: The CKD-REIN Study

Prognostic Influence of Physical Activity and Sedentary Behavior in Patients with CKD: The CKD-REIN Study

Relationships Between Sedentary Behavior, Physical Activity And Body Composition With Bone Mineral Density In Postmenopausal Women

Relationships Between Sedentary Behavior, Physical Activity And Body Composition With Bone Mineral Density In Postmenopausal Women

Sleep quality in secure psychiatric healthcare: Inpatient & staff perspectives

The lived experiences of psychiatric inpatients are not well represented in the literature, especially when these experiences pertain to health. Reports regarding sleep health are particularly sparse, despite the increasing prevalence of sleep disorders in this population. The current study aimed to explore inpatient and staff perspectives of inpatient sleep quality to aid the future development of a sleep quality intervention. Fourteen inpatients (average age 43 years, 36 % female) were recruited for individual interviews and eleven staff members were recruited for three focus groups, from a secure psychiatric hospital (England). A semi-structured interview guide facilitated discussions regarding the prevalence and type of inpatient sleep problems, existing support for inpatient sleep problems including medication, and the bidirectional relationships between nighttime sleep and daytime behaviours, such as napping and physical activity. Using reflexive thematic analysis, four themes were developed: Irregular Sleep Schedules, Nighttime Disruptions, The Patient's Bedroom, and Keeping a Routine & Staying Physically Active. Study results can be utilised when developing inpatient sleep interventions, which were identified within the study as being sorely needed. Such interventions could focus on managing daytime sleeping, sedentary behaviour, and physical activity, in order to support good sleep hygiene, foster regular sleep/wake cycles, and improve overall health.

Covid 19 Pandemic Era And Sedentary Behavior

Covid 19 Pandemic Era And Sedentary Behavior