The increasing prevalence of remote work, accelerated by the COVID-19 pandemic, has brought significant information security challenges to organizations. While remote work offers numerous benefits such as flexibility and increased productivity, it also introduces unique risks, particularly in safeguarding sensitive data. The absence of traditional office security measures and reliance on potentially insecure home and public networks heighten these risks. Organizations must implement robust strategies, including the use of Virtual Private Networks (VPNs) and multi-factor authentication (MFA), to ensure secure communications and access to corporate systems. Additionally, the protection of devices used in remote work is critical, necessitating clear security policies, regular updates, and employee training on recognizing threats like phishing and malware. Studies by Kolomoets (2022) and Alsayfi and Alsirhani (2023) highlight the importance of addressing the increased risks associated with remote work, particularly the potential for data breaches due to the lack of direct access to comprehensive security controls. These studies recommend best practices such as secure password management and regular employee training to mitigate these threats. Tanriverdi and Metin (2021) emphasize the need for renewed focus on security awareness and behavior as remote work becomes the norm. Furthermore, Rakha (2023) explores the legal implications and best practices for maintaining cybersecurity in remote settings, while Livshitz (2022) focuses on data privacy challenges, providing insights into regulatory compliance and security audits. In conclusion, safeguarding information security in remote work environments requires a holistic approach that integrates technology, continuous education, and stringent security policies. Organizations must prioritize these efforts to protect sensitive data and maintain privacy in an increasingly remote workforce.