Project: It was recognized that a team approach to eliminate CLABSIs in our 13 and 16 bed ICUs was necessary. All components of the CL bundle recommended by the Institute for Healthcare Improvement (IHI) were implemented in 2006. CLABSI rates remained unacceptable. The CLABSI Team re-convened in 2008 to review current processes related to CLABSI prevention, recommend changes to current practice, identify resources needed, and implement andmonitor new practices. A gap analysis was done and found that CL insertion practice varied from unit to unit, CL cart was used inconsistently, time out sheet not always available, RNs did not feel empowered to stop a procedure when they observed a break in technique, practice was not compatible with policy, and securement device was not always used. Actions taken included: standardized CL cart available, daily baths with CHG impregnated cloths, resident training for CL insertion in Simulation Center, 2-person team for PICC insertions, daily line assessment, details of every CLABSI patient reviewed at the BSI Team and two additional committees. A system-wide team to examine CL maintenance issues began in October 2010. Objectives are to standardize cap, dressing, and tubing change policy/practice, reduce/batch blood draws through lines, use CL dressing with incorporated securement device/CHG, and educate staff on Scrub the Hub, dedicated TPN port, limiting blood draws, and how to stop a procedure when technique is breached.