ABSTRACT The present study aimed to investigate the roles of psychological strength and attachment styles to God in predicting Covid-19 anxiety in Iranian nurses. A descriptive cross-sectional study was carried out on 100 nurses in July 2021. The subjects answered the questionnaires of psychological strength, attachment to God, and anxiety of Covid-19. The results showed a negative correlation between psychological strength and Covid-19 anxiety (r = −.894; p < .01) and a negative correlation between secure attachment style and Covid-19 anxiety (r = −.522; p < .01). But the correlation between avoidant attachment styles(r = .387;p < .01) and ambivalent attachment styles(r = .312; p < .01) with Covid-19 anxiety was positive. Also, the coefficient of determination showed that the components of psychological strength and attachment styles to God up to 81% can explain the variance of Covid-19 anxiety. Based on the research results, by investing in attachment styles to God and promoting psychological strength, we can take steps to reduce Covid-19 anxiety in nurses.