This study proposes and simulates a smart system that can be used in production car seats to decrease whiplash risk in rear-end crashes. A sliding seat incorporating a semiactively controlled magnetorheological (MR) damper model positioned under the seat-pan is simulated with a validated biofidelic human body model. Since this is the first study that demonstrates a computer controlled anti-whiplash car seat system to the best of the authors’ knowledge, a benchmark analysis is carried out to compare the proposed semiactive seat with a state-of-the-art passive anti-whiplash car seat using 23 different crash pulses, including the moderate and high severity crash pulses within the European New Car Assessment Program (EuroNCAP) whiplash risk assessment framework. The proposed semiactive design outperforms the passive seat design by further reducing the values of the critical EuroNCAP whiplash criteria, such as NIC and Nkm, together with the loads acting on the upper neck. The semiactive seat lowers the upper-neck shear force by an amount of 4 kg and 7 kg while lessening the NIC by 10% and 21% and Nkm by 9% and 56% for the EuroNCAP crash pulses, having a delta-V of 16 km/h and 24 km/h, respectively. The findings presented in this paper can aid in the design of car seats to further mitigate whiplash risk in rear-end crashes.