Acephate as a spray and dust was evaluated in 1971–72 for control of the green peach aphid, Myzus persicae (Sulzer), tobacco budworm, Heliothis virescens (F.), and tobacco hornworm, Manduca sexta (L.), on cigar-wrapper and flue-cured tobaccos. Season-long control of the 3 insects was effective with 6–7 applications at rates ranging from 0.72–1.11 lb AI/acre. In 1972, samples of green, cured, and fermented cigarwrapper and cured flue-cured tobaccos were analyzed for residues of acephate and its metabolite, Ortho 9006 (O, S-dimethyl phosphoramidothioate), after application of acephate insecticide. Residues of acephate and Ortho 9006 on the green leaf were 15.7 and 1.3 ppm, respectively, 14 days after the last of 6 spray applications at 1.01 lb AI/acre. No residue of the 2 compounds was found on the cured leaf of either tobacco. This insecticide loss probably was caused by the elevated temperatures during the curing and fermentation processes.