The Eggvin Bank (Central Norwegian-Greenland Sea, latitude ∼71°N) is a topographically anomalous shallow area with scattered volcanic peaks extending between the island of Jan Mayen and East Greenland and straddling the northern segment of the mid-Atlantic Kolbeinsey Ridge axis. Basalts dredged from the Eggvin Bank range from variably depleted, tholeiitic, near-axis lavas to enriched, transitional-to-alkaline, off-axis seamount lavas. In terms of normalised incompatible element patterns, the most depleted, near-axis tholeiite is similar to neighbouring Kolbeinsey Ridge basalts, whereas the off-axis, transitional-to-alkaline lavas are similar to other alkaline basalts occurring close to the Eggvin Bank region, e.g., those of Jan Mayen. 40Ar/39Ar step heating data indicate that the off-axis seamount lavas are coeval with other alkaline lavas erupted in the Central Norwegian-Greeland Sea at ca. 0.6–0.7 Ma. In contrast, the Eggvin near-axis tholeiites are <0.1 Ma. Volcanic peaks west and north of Jan Mayen show no indication of a systematic age progression. Therefore, the Jan Mayen hot spot hypothesis is not supported by the available radiometric age data. Sr, Nd, and Pb isotope compositions of near-axis and off-axis Eggvin Bank lavas are distinct, implying differences in their mantle sources. Isotope ratios of the off-axis basalts (87Sr/86Sr=0.70344–0.70352, 143Nd/144Nd=0.51283–0.51288, 206Pb/204Pb=18.82–18.85) resemble those of neighbouring alkali basalt occurrences, however, isotope ratios of the near-axis tholeiites correspond to lavas erupting in the south-eastern volcanic zone of Iceland, e.g., at Vestmannaeyjar. The near-axis tholeiites are generated by an unusual source with highly radiogenic Pb (206Pb/204Pb=18.95) together with relatively radiogenic Nd (143Nd/144Nd=0.51295) and low-radiogenic Sr (87Sr/86Sr=0.70314), respectively, representing an unique composition in the mantle north of central Iceland. The overlap in isotope compositions between Eggvin Bank near-axis tholeiites and south-east Iceland alkaline lavas could be an indication that the Eggvin Bank tholeiite source was derived from the Iceland plume and that it was emplaced in the upper mantle by the original Iceland plume head during the Early Tertiary as suggested by Trønnes et al. [Trønnes, T., Planke, S., Sundvoll, B., Imsland, P., 1999. Recent volcanic rocks from Jan Mayen: low degree melt fractions of enriched north-east Atlantic mantle. J. Geophys. Res. 104, 7153–7167]. Isotope and trace element data indicate an abrupt change in source composition along the Kolbeinsey Ridge axis at latitude ca. 70.6°N, apparently reflecting a boundary between two chemically distinct mantle domains with limited interaction. Based on Pb versus Pb isotope diagrams, no dispersion of enriched material is observed adjacent to the hypothetical Jan Mayen/Jan Mayen Platform plume, neither to the north-east along the Southern Mohns Ridge nor to the south along the Central Kolbeinsey Ridge.