In closing, I would reiterate that with the inevitable restructuring of departments of internal medicine, now is the time to develop innovative, interdisciplinary strategies to manage across boundaries. Strategies of vertical and horizontal integration within an academic health center and its alliance with the communities it serves. Strategies that will enhance our missions in patient care, education, and research. Recreate the environment that will once again allow nature to flourish. D During this time of reform we are not strapped with sustaining the status quo. Opportunities for innovation abound. Innovation demands an ability to reallocate and adapt. Abandon old paradigms. Seize the occasion to reformulate, restructure, revitalize, and revamp—to write a new chapter. We are limited only by our creative potential and entrepreneurial spirit, or willingness to take risk. I ask you, who better than academic health centers to succeed in managed care? Corporate relationships between medical school and hospital already exist, and with innovative restructuring seamless delivery of high-quality care is a reasonable expectation. Seize the opportunity. I ask you, who better than departments of internal medicine to provide innovative answers to seamless delivery of primary and specialty care? But vision begets responsibilities. In formulating plans of reform we must rise to the challenge of solving critical societal needs. Medically underserved populations should be targeted for high-quality health care. Community-based patient-centered programs of education, research, and preventive medicine must be provided. Research can be the friend of cost containment. In placing a premium on synergies that will increase our potential, our productivity, and effectiveness in a culture of cooperation, common purpose, and mutual education, new knowledge for the twenty-first century will emerge and of which we can be justifiably proud. It will guarantee our viability. It will be our legacy.