Idiopathic Scrotal Calcinosis Research Articles

Idiopathic scrotal calcinosis: Is cytological diagnosis enough?

Idiopathic scrotal calcinosis: Is cytological diagnosis enough?

Massive Idiopathic Scrotal Calcinosis

Idiopathic scrotal calcinosis is a rare, benign condition with the presence of multiple slow-growing yellowish-white calcified asymptomatic nodules that appear within the scrotal skin. The disease affects patients in childhood or early adulthood. The etiology of idiopathic scrotal calcinosis is still controversial. It can extensively affect the scrotal skin, but primary closure is usually achievable with good esthetic outcomes.

Scrotal Calcinosis: A Case Report and Review of Pathogenesis and Surgical Management

Idiopathic scrotal calcinosis is an uncommon benign disorder of the scrotal skin which is characterized by multiple calcified intradermal nodules. We report a 33-year old with asymptomatic multiple calcified scrotal skin nodules. He had wide excision of the lesions and direct closure of the scrotum. We review the pathogenesis and surgical treatment options for this rare disease of the scrotum.

Idiopathic scrotal calcinosis: report of two cases and review of literature

Idiopathic scrotal calcinosis: report of two cases and review of literature

Idiopathic scrotal calcinosis; a rare scrotal tumour: A Case Report and Review of Literature

Idiopathic scrotal calcinosis is a rare benign disease characterized by multiple, asymptomatic and painless nodules on the scrotum. We herein report this rare disease in a Nigerian adult male and briefly review the relevant literature.

Idiopathic Calcinosis of the Scrotum

Idiopathic Calcinosis of the Scrotum

Idiopathic Calcinosis of the Scrotum

Idiopathic Calcinosis of the Scrotum

Idiopathic calcinosis of the scrotum

Idiopathic calcinosis of the scrotum

Idiopathic Scrotal Calcinosis: Surgical Treatment and Histopathologic Evaluation of Etiology

Patients with idiopathic scrotal calcinosis present with multiple, asymptomatic calcified nodules on the scrotum that appear in childhood or early adulthood. The scrotal skin can be extensively affected, and scrotal reconstruction with complicated procedures usually seems to be needed after excision. However, primary closure is usually achievable. Two cases are presented with histopathologic findings of scrotal calcinosis. The possible etiologies are discussed, and the therapeutic alternatives are reviewed.

Idiopathic scrotal calcinosis: a report of four cases and review of the literature

Idiopathic scrotal calcinosis: a report of four cases and review of the literature

Scrotal calcinosis: is it idiopathic?

Idiopathic calcinosis of the scrotum is a rare condition, and its pathogenesis remains unknown. We recently examined 3 patients in whom scrotal epidermoid cysts in varying stages of inflammation coexisted with scrotal calcinosis. Some cysts revealed calcification of their keratin contents with little evidence of active inflammation. Other cysts showed rupture of their epithelial walls associated with the presence of keratin fibers and calcium granules in the surrounding dermis. We found that this disorder is not idiopathic and that epidermal inclusion cysts constitute the basic abnormality.

Idiopathic scrotal calcinosis - a case report with review of literature

Idiopathic scrotal calcinosis - a case report with review of literature

Idiopathic Calcinosis of the Scrotum

Idiopathic Calcinosis of the Scrotum

Idiopathic calcinosis of the scrotum: report of five cases and review of the literature

Although calcinosis of the scrotum was first described in 1883 by Lewinski [1] its nature and cause have remained elusive. Hutchinson in 1888 [2], emphasized that these calcific masses appear with no evidence of underlying cause. Various theories regarding the etiology and pathogenesis of the condition have been proposed, non has been widely accepted. “Idiopathic scrotal calcinosis” (ICS), a term applied by Shapiro in 1970 [3], is most commonly used. About 118 cases have been reported. A series of five cases is reported in which scrotal calcinosis developed. A review of the literature and a discussion on the etiology in this disease is also included.

LONG‐TERM EXPERIENCE WITH SCLEROTHERAPY FOR TREATMENT OF EPIDIDYMAL CYST AND HYDROCELE

Symptomatic testicular hydrocele and cyst of the epididymis may be treated with either operation or sclerotherapy. The current report presents the experience of a 9 year prospective study using sodium tetradecyl sulphate (STD) sclerotherapy for the treatment of symptomatic hydrocele and/or epididymal cyst. A total of 102 lesions were treated during the study period, with an initial success rate of 76% which improved to 94% with multiple treatments. The overall median follow up during the study was 30 months (range 2-100). Sclerotherapy offers a cost-effective outpatient method for the treatment of symptomatic scrotal cysts.

Intrascrotal Epidermoid Cyst With Extension into the Pelvis

An 8-year-old boy presented with an asymptomatic extratesticular, scrotal epidermoid cyst with extension across the urogenital diaphragm into the pelvis. While routine contrast studies and ultrasound were performed, magnetic resonance imaging was most useful in depicting the anatomical boundaries of the lesion, including the intrapelvic extension. Complete excision was performed transcrotally. The lesion is histologically indistinguishable from epidermoid cysts found elsewhere in the external genitalia, that is the penis, scrotum or testis. The etiology is unknown but it may represent a monolayer teratoma of germ cell origin or abnormal embryological closure of the median raphe.

Idiopathic Calcinosis of the Scrotum–a Specific Entity of the Scrotal Skin

A 69 year old patient with relapsing idiopathic scrotal calcinosis (ICS) is presented. Histological evaluation of the excised material showed the typical morphological features of calcified material within the corium. A review of the literature revealed 12 of 75 patients who had evidence of epithelial lining of the corial calcifications. Generally the calcified masses were surrounded by granulation tissue with mononuclear and foreign body giant cells. There is accumulating evidence for dystrophic calcification of cyst rather than an idiopathic genesis.

DESMOPLASTIC TRICHOEPITHELIOMA AND MULTIPLE EPIDERMAL CYSTS

A 22‐year‐old peanut vendor presented with an asympto‐matic annular plaque of 2 years duration on his face. It began as a small, firm papule and gradually increased in size and extent. His occupation involved long hours of ex‐posure to sunshine, but there was no associated burning sensation or irritation.Dermatologic examination revealed an oval, annular plaque over the right temple, about 4 cm × 3 cm. The rim was studded with miliary white papules 1 to 2 mm in size, and the center was depressed (Fig. 1). It had an indurated feel and was freely mobile over the underlying structures. Clinically, a differential diagnosis of colloid milium, granu‐loma annulare, or annular elastolytic granuloma was enter‐tained. In addition, numerous milia were scattered over the cheeks. He also had multiple, well‐defined, firm, white scro‐tal swellings, 1 to 3 cm in size. Systemic examination did not reveal any abnormality.Skin biopsies of the plaque and a scrotal cyst were per‐formed, and the sections stained with hematoxylin and eosin. The annular plaque, showed mild hyperplasia of the epidermis, numerous keratin cysts, islands of basophilic cells in the dermis, and abundant fibrous tissue compress‐ing the tumor cells into narrow strands (Fig. 2). Tumor stro‐mal retraction was conspicuous by its absence. A diagnosis of desmoplastic trichoepithelioma was made.The scrotal nodule revealed an epidermal cyst lined by stratified squamous epithelium and containing laminated keratin (Fig. 3). The patient was referred to the department of plastic surgery, where the plaque was excised in toto, and the defect repaired.

A Case of Idiopathic Vulvar Calcinosis: The First in Japan

Idiopathic calcinosis of the scrotum is a rare condition of unknown etiology. As counterparts of this male disorder, only two female cases have been reported. We report a third case, the first of its kind, in Japan. Histochemical stains revealed acid mucopolysaccharide (acid-MPS) within the calcinosis and many infiltrated mast cells near it; these might histogenese the calcium deposition. Immunohistochemically, polyclonal carcinoembryonic antigen (CEA) and keratin stains revealed no positive cells near the calcium depositions.

Idiopathic scrotal calcinosis is idiopathic

The appearance of calcific masses within the dermis of scrotal skin is generally referred to as idiopathic scrotal calcinosis. There has been some debate about the pathogenesis of these calcium deposits. This debate centers on the question of whether the calcium deposition is truly idiopathic or whether it occurs as a result of preexisting epidermal cysts. We have performed immunohistochemical staining for keratin in nine patients with apparent idiopathic scrotal calcinosis and have found no evidence of keratin in the dermal tissue immediately adjacent to the calcium deposits. We conclude that idiopathic scrotal calcinosis is idiopathic.