Screening Intentions Research Articles

Confusion and Anxiety Following Breast Density Notification: Fact or Fiction?

In the absence of evidence-based screening recommendations for women with dense breasts, it is important to know if breast density notification increases women’s anxiety. This study describes psychological reactions and future screening intentions of women attending a public mammographic screening program in Western Australia. Two-thirds of notified women indicated that knowing their breast density made them feel informed, 21% described feeling anxious, and 23% confused. Of the notified women who reported anxiety, 96% intended to re-screen when due (compared to 91% of all notified women and 93% of controls; p = 0.007 and p < 0.001, respectively). In summary, reported anxiety (following breast density notification) appears to increase women’s intentions for future screening, not the reverse.

Intention to Screen for Alzheimer's Disease by Residential Locale.

A random digit dialing sample from Missouri (USA) was used to compare associations between psychosocial factors and Alzheimer’s disease (AD) screening intention based on residential locale. Linear regression associations between demographics and five psychosocial constructs (dementia knowledge, perceived screening benefits, preventive health behaviors, perceived susceptibility, and self-efficacy) and screening intention were compared by residential locale. Participants (n = 932) had a mean age of 62 years (urban: n = 375; suburban: n = 319, rural: n = 238). African Americans more often lived in urban than suburban/rural neighborhoods, and more urban than suburban/rural residents reported insufficient income. Preventative health behaviors (e.g., dentist visits) were higher in urban and suburban versus rural participants. AD screening intention did not differ by residential locale. Among urban participants, self-efficacy to get screened was associated with screening intention. Among rural participants, dementia knowledge was associated with screening intention. Perceived screening benefits and perceived susceptibility to AD were associated with screening intention regardless of locale. Unlike urban participants, rural participants demonstrated greater screening intention with greater dementia knowledge. Our findings suggest that psychosocial factors associated with AD screening intention differ depending on residential locale. Strategies to increase dementia screening may need to account for regional variations to be maximally effective.

Intention to Screen for Cervical Cancer in Debre Berhan Town, Amhara Regional State, Ethiopia: Application of Theory of Planned Behavior

Background Cervical cancer is a major public health problem in many developing countries. Despite the value of screening to prevent morbidity and mortality from cervical cancer, little available literature shows early detection and treatment to be limited in Ethiopia. The aim of this study was to determine the magnitude of and identify factors associated with women's intention to screen for cervical cancer using the theory of planned behavior. Methods A community-based cross-sectional study design supplemented with a qualitative approach was employed. Using multistage sampling, a total of 821 women were used in the study. An interviewer-administered survey questionnaire was used to collect quantitative data, whereas purposively selected 12 female health care providers were included in in-depth interviews. Descriptive statistics and simple and multiple binary logistic regression analysis were used to determine the magnitude of women's intention, identify associated factors, and explore barriers for intention to cervical cancer screening among Debre Berhan women, Ethiopia. The statistical association was determined at a P value of less than 0.05. Moreover, thematic analysis was used to search the hindrances of women's intention to screen for cervical cancer. Results The median age of women who participated in this study was 39 years with IQR of 35 to 42 years. Three hundred sixty-one (361, 45.3%) of women had an intention to screen for cervical cancer within three months from the date of the interview. Positive attitude towards cervical cancer screening (AOR = 6.164; 95% CI: 4.048, 9.387), positive subjective norm (AOR = 2.001; 95% CI: 1.342, 2.982), and higher perceived behavioral control (AOR = 7.105; 95% CI: 4.671, 10.807) were predictors of the women's intention to screen for cervical cancer. The qualitative finding revealed that women did not like to be screened for cervical cancer because they thought that procedure pinch the cervix and it may result in perforating the uterus that would expose them for infertility. In addition, the qualitative findings supported quantitative results, where the constructs of the theory of planned behavior play an essential role in the betterment of women's intention. Conclusion This study showed that women's intention to screen for cervical cancer was low. Positive attitudes towards cervical cancer screening (CCS), subjective norms, and perceived behavioral control were predictors of women's intention to screen for cervical cancer. Thus, efforts should be exerted to improve the attitude of women involving influential people, which could improve women's intention for cervical cancer screening. Moreover, behavioral change communication focusing on the constructs of the theory of planned behavior is crucial.

Clustering of chronic hepatitis B screening intentions in social networks of Moroccan immigrants in the Netherlands

BackgroundEarly detection, identification, and treatment of chronic hepatitis B through screening is vital for those at increased risk, e.g. born in hepatitis B endemic countries. In the Netherlands, Moroccan immigrants show low participation rates in health-related screening programmes. Since social networks influence health behaviour, we investigated whether similar screening intentions for chronic hepatitis B cluster within social networks of Moroccan immigrants.MethodsWe used respondent-driven sampling (RDS) where each participant (“recruiter”) was asked to complete a questionnaire and to recruit three Moroccans (“recruitees”) from their social network. Logistic regression analyses were used to analyse whether the recruiters’ intention to request a screening test was similar to the intention of their recruitees.ResultsWe sampled 354 recruiter-recruitee pairs: for 154 pairs both participants had a positive screening intention, for 68 pairs both had a negative screening intention, and the remaining 132 pairs had a discordant intention to request a screening test. A tie between a recruiter and recruitee was associated with having the same screening intention, after correction for sociodemographic variables (OR 1.70 [1.15–2.51]).ConclusionsThe findings of our pilot study show clustering of screening intention among individuals in the same network. This provides opportunities for social network interventions to encourage participation in hepatitis B screening initiatives.

The impact of emotion‐based mass media campaigns on stigma toward cervical screening non participation

AbstractNumerous studies have demonstrated the positive impact of mass media coverage of cancer on screening rates. In this online experiment, we assessed the influence of different types of mass media news articles (factual vs. emotive narratives) on cervical cancer screening intentions. We also tested the process through which mass media news articles influence screening intention. Participants (N = 141) were randomly allocated to receive either a news article containing factual information about screening, a news article containing an emotive narrative about a nonfamous woman who died after not being screened, or no information about screening. Participants, then, completed measures of stigma, fear, shame, and screening intention. Stigma toward people who had not been screened (i.e., public stigma) was greater when participants received an emotive narrative rather than factual information or no information. Moreover, we found a significant indirect effect of the manipulation on screening intention via public stigma. These results indicated that the emotive news article increased public stigma, which in turn predicted screening intention. Based on this, we argue that it is important to carefully consider the type of narrative that is included in mass media articles to ensure that it does not stigmatize people who have not been screened.

Self-efficacy and importance of participation reasons as predictors for prostate cancer screening intention in African American men

ABSTRACT Objective: African American men have higher lifetime risk of developing prostate cancer (PCa), and face more health burdens from this disease due in part to limited participation in cancer screening. Therefore, it is important to study psychosocial factors associated with screening intention in African American men. Guided by social cognitive theory, the current study aims to examine the role of self-efficacy and importance of participation reasons as predictors of PCa screening intention in African American men. Design: This is a primary analysis using data collected from African American men in northeast Ohio and the Southeastern United States. PCa screening intention and self-efficacy were measured by single-item questions. Importance of participation reasons was measured in four domains: psychological, convenience, awareness, and medical. Hierarchical binary logistic regression was used to predict PCa screening intention in African American men. Results: The sample size was 174. The average age was 46.52. Adding self-efficacy and reasons for participation significantly improved prediction for PCa screening intention in African American men (Δχ 2 = 55.28, p < .001). The final model had χ 2 = 69.63 (p < .001). Higher self-efficacy (OR = 2.56, p < .05), more perceived importance of psychological reasons (OR = 2.42, p < .001) and medical reasons (OR = 1.10, p < .05) were significant predictors. Also, the perceived chance of developing PCa predicted higher odds of PCa screening intention. Conclusions: Enhancing self-efficacy might be an important intervention focus for African American men to improve PCa screening intention. In addition, the findings suggest that African American men intend to have PCa screening because they experience worries or physical symptoms, and unlikely because it is convenient to get screening or recommended by family members and friends. Thus, intervention efforts could focus on enhancing PCa knowledge and informed decision-making about PCa screening among African American men.

Social media and mobile health technology for cancer screening: a systematic review and meta-analysis protocol

IntroductionCancer is one of the leading causes of death globally and many jurisdictions have developed population-based cancer screening programmes to reduce the public health burden of disease. However, screening participation...

Giant Inflatable Colon Model Enhances Lebanese Community Knowledge and Intention for Colorectal Cancer Screening

PURPOSETo assess the knowledge and intention for colorectal cancer (CRC) screening within the Lebanese community before and after a guided tour through an inflatable colon model.METHODSThe Cancer Prevention and Control Program, Naef K. Basile Cancer Institute at the American University of Beirut Medical Center in collaboration with AMALOUNA educational nongovernmental organization launched awareness campaigns during which a walk-through inflatable colon was displayed. Pre- and post-surveys related to the age of screening, risk factors, symptoms, and CRC prevention were collected anonymously before and after touring the inflatable colon to assess the effectiveness of this educational tool.RESULTSCompiled data collected from 782 participants revealed that older age and higher education were predictors of favorable CRC screening knowledge and behaviors before entering the inflatable colon. Interestingly, touring the inflatable colon model significantly improved participants’ awareness and knowledge about CRC. Most importantly, it increased their willingness for screening and social engagement and comfort discussing and promoting CRC screening.CONCLUSIONOverall, these results indicate that the interactive colon is an effective educational tool that can make a positive impact by improving the community CRC awareness and interest in CRC screening. They also highlight the importance of such educational efforts conducted in the community to create more awareness about CRC and emphasize the importance of its prevention.

The Effects of Personalizing Colorectal Cancer Risk Communication on Risk Perceptions and Health Behavior Intentions: a Randomized Trial of Average-Risk Adults.

Risk assessment tools may help individuals gauge cancer risk and motivate lifestyle and screening behavior changes. Despite the evermore common availability of such tools, little is known about their potential utility in average-risk population approaches to cancer prevention. We evaluated the effects of providing personalized (vs. generic) information concerning colorectal cancer (CRC) risk factors on average-risk individuals' risk perceptions and intentions to engage in three risk-reducing behaviors: CRC screening, diet, and physical activity. Further, we explored whether the receipt of CRC-specific risk assessment feedback influenced individuals' breast cancer risk perceptions and mammography intentions. Using an online survey, N = 419 survey respondents aged 50-75 with no personal or family history of CRC were randomized to receive an average estimate of CRC lifetime risk and risk factor information that was either personalized (treatment) or invariant/non-personalized (control). Respondent risk perceptions and behavioral intentions were ascertained before and after risk assessment administration. No differences were observed in risk perceptions or behavioral intentions by study arm. However, regardless of study arm, CRC screening intentions significantly increased after risk assessment feedback was provided. This occurred despite a significant reduction in risk perceptions. Results support the role simple cancer risk assessment information could play in promoting screening behaviors while improving the accuracy of cancer risk perceptions. Providing cancer risk assessment information may decrease individuals' perceptions of cancer risk to more realistic levels while simultaneously facilitating screening intentions among an average-risk population, regardless of whether provided risk information is personalized.

Screening Motives among Attendants of Breast Cancer-Early Detection Clinics, in Iraq

Background and Objectives: The early detection model for breast cancer in Iraq is a combined program of an early diagnosis for symptomatic attendants and an opportunistic unsystematic breast clinical examination screening that mainly depend on attendants’ request. With an aim to initiate breast cancer screening program, the current study’s objective is to illustrate the prevalence and motives of screening behavior among attendants.Method: A cross sectional study was conducted for a period of three months, interviewing 500 randomly selected attendants of two breast cancer early detection clinics in Baghdad city. Data presented in frequency and percentages and analyzed by binary logistic regression, P ? 0.05 reflected a significant association.Results: The results showed that only 42 (8.4%) attended the breast clinics with screening intention. Being employed (OR= 3.198; 95% C.I.= 1.284 – 7.964; P=0.013) or a student (OR=6.605; 95% C.I.= 1.125 – 38.759; P=0.037), of high socioeconomic status (OR=2.695; 95% C.I.= 1.036 –7.012; P =0.042) and having a positive family history of breast cancer (OR= 5.17; 95% C.I.= 2.466 –10.855; P &lt;0.001) were significant reasons for breast cancer screening.Conclusions: Reforming the health system and tackling access barriers to screening should be endorsed through applying multiple components interventions to increase women participation in the service with a special focus on the less empowered under-served ones.

The Related Factors on Cervical Cancer Screening Intention among Married Immigrant Women based on the Health Belief Model

The Related Factors on Cervical Cancer Screening Intention among Married Immigrant Women based on the Health Belief Model

Labor Market Screening and Social Insurance Program Design for the Disabled

We evaluate social insurance program designs for the disabled by empirically implementing a frictional labor market model with screening employment contracts. In the model, firms post a screening contract consisting of wage and job amenities, and workers with different levels of disability make labor supply decisions. We first theoretically analyze the optimal structure of disability insurance (DI) and firm subsidies for hiring the disabled. Then, by exploiting policy variation in hiring subsidies for the disabled, we empirically examine which job amenities may be used by firms to screen out the disabled, and we structurally estimate our equilibrium model. Using the estimated model, we quantitatively explore the optimal joint design of DI and firm subsidies for employing disabled workers. We find a welfare improving role of firm subsidies that encourage firms to provide more job amenities, mitigating the labor supply disincentives of DI and labor market distortions induced by firms screening contracts. Finally, we show that the presence of a firm's screening incentive significantly affects the effectiveness of the policies: the optimal level of DI should be higher to ameliorate contract distortions caused by the firm's screening activities.

Predictors of intention translation in flexible sigmoidoscopy screening for colorectal cancer.

This prospective study aimed to identify predictors of intention and subsequent attendance of flexible sigmoidoscopy screening using constructs derived from the Health Belief Model (HBM). A total of 4,330 people aged 54 years and registered at 1 of 83 participating English general practices were sent a preinvitation questionnaire to assess sociodemographics, HBM variables including perceived benefits, barriers, seriousness, health motivation, and external cues to action as well a range of other constructs and personal characteristics known to relate to cancer screening. Of the 1,578 respondents (36.4%), 1,555 (98.5%) answered the intention question: 52.9% stated definitely yes, 38.1% probably yes, 6.8% probably not, and 2.2% definitely not. Intentions were positively associated with a higher score on a scale of benefits (odds ratio [OR] = 4.62; 95% confidence intervals [CI; 3.24, 6.59]) and health motivation, that is, interest in other ways of preventing colorectal cancer (OR = 2.61; 95% CI [1.62, 4.22]), while a higher score on perceived barriers (OR = 0.19; 95% CI [0.12, 0.31]) and currently following recommended healthy lifestyle behaviors (OR = 0.31; 95% CI [0.16, 0.59]) were negatively associated. Attendance was verified for 922 intenders (65.2%) of whom 737 (79.9%) attended. Attendance was predicted by health motivation (OR = 1.75; 95% CI [1.07, 2.86]), perceived benefits (OR = 1.82; 95% CI [1.37, 2.43]), perceived barriers (OR = 0.47; 95% CI [0.32, 0.69]), individual-level deprivation (OR = 0.26; 95% CI [0.14, 0.50]), and having diabetes (OR = 0.48; 95% CI [0.25, 0.94]). This study supported the usefulness of the HBM in predicting cancer screening and was further enhanced by adding non-HBM variables such as individual socioeconomic deprivation and comorbidities. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

The Effect of Behavioral Relaxation Training on Distress and Cancer Screening Intention of Patients with Upper Gastrointestinal Endoscopy

Purpose: This study evaluates the effect of behavioral relaxation training on distress and cancer screening intention of patients with upper gastrointestinal endoscopy. Methods: The research was conducted in a non-equivalent control group posttest design. Data were collected from endoscopy subjects in B city from October to November of 2018. Fifteen minutes of behavioral relaxation training were provided to the experimental group (n=40) and traditional relaxation therapy methods were provided to the control group (n=40). Outcome measures were distress and cancer screening intention of patients with upper gastrointestinal endoscopy. Data were analyzed with a ${chi}^2$-test, independent t-test, Fisher's exact test with SPSS/PC version 23.0. Results: The objective discomfort (t=8.81, p&lt;.001) of the experimental group was lower than that of the control group; there were no significant differences in the subjective discomfort (t=1.73, p=.088). The cancer screening intention (t=-5.85, p&lt;.001) of the experimental group was significantly higher than that of the control group. Conclusion: Behavioral relaxation training was effective in heightening cancer screening intention. Therefore it can be usefully applied to increase cancer screening intention.

Sexual behaviors and intention for cervical screening among HPV-vaccinated young Chinese females

Background and objectivesHuman papillomavirus (HPV) vaccination and cervical screening prevent cervical cancer effectively. However, there are concerns whether vaccination leads to high-risk sexual behaviors and less intention for cervical screening. We aimed to evaluate the influence of HPV vaccination on high-risk sexual behaviors, and intention for cervical screening among young Chinese females. We also reported the latest HPV vaccination uptake in Hong Kong. MethodsA population-based survey was conducted between September 2016 and January 2017. Subjects were school-age girls from twenty-five secondary schools (in-school) and community females between 18 and 27 years (out-school). Demographics, vaccine-related attitudes, intention for cervical screening and participants’ sexual behaviors were examined. ResultsWe surveyed 2260 females from in-school (n = 1664) and out-school (n = 596) settings. 11.5% in-school and 23.5% out-school participants received at least one dose of HPV vaccine. Vaccination was not associated with age (in-school Odds Ratio [OR] 0.99, p = 0.87; out-school OR 1, p = 0.94), ethnicity (in-school OR 0.82, p = 0.72; out-school OR 0, p = 0.98), maternal education (in-school OR for secondary school 1.19, p = 0.43; for post-secondary school 1.28, p = 0.48), underage sex (in-school OR 1.22, p = 0.80; out-school OR 0.63, p = 0.67), earlier sexual exposure (in-school β 0.01, p = 0.99; out-school β 0.13, p = 0.68), multiple sex partners (in-school OR 3.27, p = 0.22; out-school OR 1.16, p = 0.43), and unprotected sex (in-school OR 1.14, p = 0.78; out-school OR 0.60, p = 0.10). Out-school females with higher personal education level was associated with higher vaccine uptake (post-secondary OR 3.4, p < 0.001; bachelor’s degree or above OR 3.71, p < 0.001). More vaccinated females intended for cervical screening (in-school 23.6% vs. 21.1%; out-school 53.6% vs. 43.6%). Costs and knowledge were important factors for non-vaccination and non-intention for cervical screening. ConclusionsHPV vaccination was not associated with earlier and high risk sexual behavior among Chinese young females. Vaccinated Chinese young females had a higher intention for cervical screening.

Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish.

Their optical clarity as larvae and embryos, small size, and high fecundity make zebrafish ideal for whole animal high throughput screening. A high-throughput drug discovery platform (HTP) has been built to perform fully automated screens of compound libraries with zebrafish embryos. A Tg(kdrl:EGFP) line, marking endothelial cell cytoplasm, was used in this work to help develop protocols and functional algorithms for the system, with the intent of screening for angiogenesis inhibitors. Indirubin 3’ Monoxime (I3M), a known angiogenesis inhibitor, was used at various concentrations to validate the protocols. Consistent with previous studies, a dose dependant inhibitory effect of I3M on angiogenesis was confirmed. The methods and protocols developed here could significantly increase the throughput of drug screens, while limiting human errors. These methods are expected to facilitate the discovery of novel anti-angiogenesis compounds and can be adapted for many other applications in which samples have a good fluorescent signal.

Exploring the Effects of Source Credibility and Message Framing on STI Screening Intentions: An Application of Prospect and Protection Motivation Theory

Roughly half of all new sexually transmitted infections (STI) occur in adolescent and college-aged populations. College students tend to underestimate their personal risks of contracting STIs. Consequently, many college students do not engage in protective behaviors that would reduce STI transmission rates. This study examined the effect of source credibility (high vs. low) and message framing (positive vs. negative) on college students’ behavioral intentions to get screened for STIs via a 2 × 2 experiment (n = 207). Further, drawing on both Prospect Theory and Protection Motivation Theory, the study tested whether coping and threat appraisals mediated the effects of source credibility and message framing on behavioral intentions. Results reveal that both highly credible sources and negatively framed messages influenced behavioral intentions to screen for STIs. However, the interaction term of source credibility by message frame was not significant. Mediation models suggested that efficacy perceptions partially explained the effect of source credibility on behavioral intentions, but not for the effect of message framing. Perceptions of severity and susceptibility did not mediate the effect of either source credibility or message framing. Practical and theoretical implications of the results are discussed.

CORRELATES OF BREAST CANCER SCREENING BEHAVIORS AMONG INDIGENOUS WOMEN

Cervical cancer remains a significant cause of morbidity and mortality among women globally; yet cancer burden is unevenly distributed among racial/ethnic groups. With 12,820 new cases in 2017 in the U.S., cervical cancer is the top cause of death among Indigenous women. Indeed, cervical cancer mortality rates among AI women in South Dakota are five times the national average and 79% higher compared to Whites in that region. This study examined predictive models of utilization of mammograms among Indigenous women adapting Andersen’s behavioral model. Using a sample of 285 Indigenous women residing in South Dakota, nested logistic regression analyses were conducted to assess predisposing (age and marital status), need (personal and family cancer history), and enabling factors (education, monthly household income, mammogram screening awareness, breast cancer knowledge, self-rated health, and cultural practice to breast cancer screening). Results indicated that only 55.5% of participants reported having had a breast cancer screening within the past 2 years, whereas 21.0% never had a mammogram test. After controlling for predisposing and need factors, higher education, greater awareness of mammogram, and higher utilization of traditional Native American approaches were significant predictors of mammogram uptake. The results provide important implications for intervention strategies aimed at improving breast cancer screening and service use among Indigenous women. Educating health professionals and Indigenous community members about the importance of breast cancer screening is highly needed. It is critical to assess a woman’s level of traditional beliefs and practices and its possible influence on screening participation and future screening intention.

Pancreatic cancer and melanoma related perceptions and behaviors following disclosure of CDKN2A variant status as a research result

PurposeThis study examined whether participants who learned research results related to a germline CDKN2A variant known to be associated with increased risk of pancreatic cancer and malignant melanoma would pursue confirmatory testing and cancer screening, share the genetic information with health care providers and family, and change risk perceptions. MethodsParticipants were pancreas research registry enrollees whose biological sample was tested in a research laboratory for the variant. In total, 133 individuals were invited to learn a genetic research result and participate in a study about the disclosure process. Perceived cancer risk, screening intentions, and behaviors were assessed predisclosure, immediately postdisclosure, and six months postdisclosure. ResultsEighty individuals agreed to participate and 63 completed the study. Immediately postdisclosure, carriers reported greater intentions to undergo pancreatic cancer and melanoma screening (p values ≤0.024). Seventy-three percent of carriers (47.5% noncarriers) intended to seek confirmatory testing within six months and 20% (2.5% noncarriers) followed through. All participants shared results with ≥1 family member. More carriers shared results with their health care provider than noncarriers (p = 0.028). ConclusionRecipients of cancer genetic research results may not follow through with recommended behaviors (confirmatory testing, screening), despite stated intentions. The research result disclosure motivated follow-up behaviors among carriers more than noncarriers.

Example B: Using online respondent-driven sampling among Moroccan immigrants in the Netherlands

Abstract The Dutch Health Council recommended chronic hepatitis B (HBV) screening for first-generation immigrants originating from intermediate/high HBV endemic countries. The Council proposed two screening strategies; individual case finding by general practitioners and local screening programmes. Our aim was to explore knowledge and information needs regarding chronic HBV and its screening among Moroccan immigrants in the Netherlands, in order to provide Dutch Municipal Health Services insights on how to inform immigrants. We also studied a randomized recruitment method using respondent-driven sampling (RDS) for a better understanding on how to reach and recruit immigrants for an online questionnaire. First- and second-generation Moroccan immigrants were asked to fill in an online questionnaire and forward this to four Moroccan contacts. Participants were randomized to one of three recruitment strategies; no incentive for filling in the questionnaire nor for successfully recruiting each contact, an incentive for filling in the questionnaire and for successfully recruiting each contact, and a gamified element as non-monetary incentive to stimulate peer-recruitment. Preliminary analyses show a sample of 59 Moroccans (17-59 years), of which 63% was second-generation and 76% was female. Of these, 46% would like to have information about chronic hepatitis B, while the average knowledge score was 5.02 (0-10). Over 60% of the participants intends to participate in chronic HBV screening, and would also recommend this to their (grand)parents. Using a monetary incentive seemed to be the best recruitment strategy in terms of the number of waves (max: 3). A gamified non-monetary incentive was least effective in stimulating peer-recruitment (max: 0). Despite the limited level of knowledge and information need, the majority of Moroccan immigrants had a positive screening intention. The next step is to determine whether our methodology could be applied to reach other immigrant groups.