Scientometric Study Research Articles

Scientometric analysis of trends in global research on acne treatment.

The present study aims to identify the main lines of research in the field of acne treatment using reproducible scientometric methods. In this article, we reviewed the following research trends: facial acne, different antibiotics, retinoids, anti-inflammatory drugs, epidermal growth factor receptor inhibitors therapy, and associated diseases. The analysis of publications from the PubMed collection was carried out from 1871 to 2022. All data were analyzed using Microsoft Excel. The evolution of the terminological portrait of the disease is shown. Trends in the use of various groups of antibiotics, retinoids, anti-inflammatory drugs, and photodynamic therapy for acne treatment have been found. There is a growing interest in clindamycin and doxycycline (polynomial and exponential growth, respectively). The effects of isotretinoin are also being studied more frequently (active linear growth). The publication of studies on spironolactone is increasing (linear growth). There is also a steady interest in the use of epidermal growth factor receptor inhibitors in the recent years. There is active research on acne and polycystic ovary syndrome (exponential growth). Only articles in English were selected. The most frequent terms were considered. The dynamics of publication activity in the field of acne was considered. The aim of the current scientometric study was to analyze the global trends in acne treatments. The trend analysis made it possible to identify the most explored areas of research, as well as indicate those areas in dermatology in which interest is declining.

Bacillus thuringiensis pesticidal toxins: A global analysis based on a scientometric study (1980–2021)

Several studies have been conducted on Bacillus thuringiensis (Bt) pesticidal toxins due to their successful environmentally friendly biopesticide activity against various insect pest orders, protozoa, mites, and nematodes. However, no existing study has systematically examined the trends and evolution of research on Bt pesticidal toxins from a scientometric perspective. This study aimed to analyze the trends and hotspots of global research in this field. 5757 publications on Bt pesticidal toxins were extracted from the Web of Science Core Collection (WoS) from 1980 to 2021. Statistical and scientometric analyses were performed using Excel, CiteSpace, and VOSviewer visualization tools to evaluate research evolution, journal contribution and subject categories, contributing countries and institutions, highly influential references, and most used author keywords. The 5757 publications featured in 917 journals spanning 116 subject categories. The top 5 subject categories ranked as Entomology, Biotechnology & Applied Microbiology, Microbiology, Biochemistry & Molecular Biology, and Agriculture. Out of these publications, the USA contributed the most, with 1562 publications, 72,754 citations, and 46.58 average citations per paper (ACPP); however, Belgium had the highest (106.43) ACPP among the top 20 contributing countries. The Chinese Academy of Agricultural Sciences is the leading institution with 298 publications and 21.20 ACPP. The Pasteur Institute is ranked first (90.04) in terms of ACPP. Keywords analyses revealed that recent studies are inclined toward the evolution of insect resistance against Bt toxins. In future, studies related to the development of resistance mechanisms by insects against Bt pesticidal toxins and ways to overcome them will likely receive more attention. This study highlights the past and current situations and prospective directions of Bt pesticidal toxins-related research.

Scientometric Research Analysis of Cleft Lip and Palate Literature: Hot Spots, Most Influential Countries/Journals, History and Future

Objective: Identifying and mapping the hotspots of the Cleft lip and palate (CLP) literature from 1980 to 2022, in addition it is aimed to present the results in a simplification. This article aims to offer an overview of pertinent research, examine prevailing research patterns, and stimulate appropriate areas for future investigation. Methods: In this scientometric research analysis, CLP publications between 1980 and 2022 were obtained from the Web of Science Core Collection database. The keywords "cleft lip and palate", "cleft lip, "cleft palate" and "oral cleft" were used in the search. CiteSpace, R-Studio (biblioshiny program) and Excel 2016 software were used for visualizations and analysis. Results: A total of 26,319 articles and 473,074 references were analyzed. The top 3 countries with the most publications were the United States (9,368 publications, 35.59% of the total), the United Kingdom (2,062, 7.83%), and Japan (1,786, 6.78%). After the co-citation clustering analysis, it was seen that the CLP literature was divided under 13 headings. The most influential articles were found with the citation burst analysis. Conclusion: Scientometric analysis study has been done in CLP's 42-year publication history. The results obtained present the general trend of the CLP literature, the topics on which the literature is divided, and the hot spots. With similar scientometric analysis studies to be carried out in the future, the progress of the literature can be followed and the future can be predicted.

Sleep Profiles in Eating Disorders: A Scientometric Study on 50 Years of Clinical Research.

Sleep and diet are essential for maintaining physical and mental health. These two factors are closely intertwined and affect each other in both timing and quality. Eating disorders, including anorexia nervosa and bulimia nervosa, are often accompanied by different sleep problems. In modern society, an increasing number of studies are being conducted on the relationship between eating disorders and sleep. To gain a more comprehensive understanding of this field and highlight influential papers as well as the main research domains in this area, a scientometric approach was used to review 727 publications from 1971 to 2023. All documents were retrieved from Scopus through the following string "TITLE-ABS (("sleep" OR "insomnia") AND ("anorexia nervosa" OR "bulimia nervosa" OR "binge eating" OR "eating disorder*") AND NOT "obes*") AND (LIMIT-TO (LANGUAGE, "English"))". A document co-citation analysis was applied to map the relationship between relevant articles and their cited references as well as the gaps in the literature. Nine publications on sleep and eating disorders were frequently cited, with an article by Vetrugno and colleagues on nocturnal eating being the most impactful in the network. The results also indicated a total of seven major thematic research clusters. The qualitative inspection of clusters strongly highlights the reciprocal influence of disordered eating and sleeping patterns. Researchers have modelled this reciprocal influence by taking into account the role played by pharmacological (e.g., zolpidem, topiramate), hormonal (e.g., ghrelin), and psychological (e.g., anxiety, depression) factors, pharmacological triggers, and treatments for eating disorders and sleep problems. The use of scientometric perspectives provides valuable insights into the field related to sleep and eating disorders, which can guide future research directions and foster a more comprehensive understanding of this important area.

Global development and future trends of artificial sweetener research based on bibliometrics

Artificial sweeteners have sparked a heated debate worldwide due to their ambiguous impacts on public and environmental health and food safety and quality. Many studies on artificial sweeteners have been conducted; however, none scientometric studies exist in the field. This study aimed to elaborate on the knowledge creation and development of the field of artificial sweeteners and predict the frontiers of knowledge based on bibliometrics. In particular, this study combined VOSviewer, CiteSpace, and Bibliometrix to visualize the mapping of knowledge production, covered 2389 relevant scientific publications (1945–2022), and systematically analyzed articles and reviews (n = 2101). Scientific publications on artificial sweeteners have been growing at an annual rate of 6.28% and globally attracting 7979 contributors. Susan J. Brown with total publications (TP) of 17, average citation per article (AC) of 36.59, and Hirsch (h)-index of 12 and Robert F. Margolskee (TP = 12; AC = 2046; h-index = 11) were the most influential scholars. This field was clustered into four groups: eco-environment and toxicology, physicochemical mechanisms, public health and risks, and nutrition metabolism. The publications about environmental issues, in particular, “surface water,” were most intensive during the last five years (2018–2022). Artificial sweeteners are gaining importance in the monitoring and assessment of environmental and public health. Results of the dual-map overlay showed that the future research frontiers tilt toward molecular biology, immunology, veterinary and animal sciences, and medicine. Findings of this study are conducive to identifying knowledge gaps and future research directions for scholars.

Evolution of Arsenic as a Toxic and Therapeutic agent through ages - A Scientometric Study

Evolution of Arsenic as a Toxic and Therapeutic agent through ages - A Scientometric Study

A scientometric study and a bibliometric review of the literature on the design and construction of semi-flexible pavement

In last years, a new type of pavement has gained popularity, this type is called Semi-Flexible Pavement (SFP). It consists of porous asphalt with high air voids between (25-35) % filled with cementitious grout materials. This type of pavement substance offers substantial advantages over both common types of pavements (concrete and flexible) such as good resistance to rutting and durability. SFP is considered an alternative pavement to exceed the drawbacks that occur for both flexible and concrete pavements. SFP has good features against permanent deformation, oil spillage, and fatigue resistance. Previous studies have shown that it can be used in a variety of applications such as highways, motorways, bridge deck pavement, tunnels, industrial areas with industrial equipment traffic, airport aprons, and stations. The goal of this research is to identify and compile the most significant research papers using the Web of Science (WOS), analyze the data using the VOS viewer software, as well as learn which countries and institutions had published the most articles relating to the subject of cementitious grout material as it relates to semi-flexible. It was also done to learn more about the authors and their collaboration. In addition to knowing the keywords that will aid researchers in their research on this topic, using these studies to better understand the elements that affect how well semi-flexible mixtures and grouts perform such as porous asphalt Mixture gradation and grout material components.

A scientometric study of chemical carcinogen-induced experimental oral carcinogenesis with emphasis on chemopreventive agents

Background/purpose4-Nitroquinoline 1-oxide (4NQO)-induced tongue carcinoma and 7,12-dimethlybenz(a)anthracene (DMBA)-induced cheek pouch carcinoma are the most common and classical chemical carcinogen-induced animal models of oral carcinogenesis. The purpose of this study was to provide the research trends and characteristics of 4NQO- and DMBA-induced experimental oral carcinogenesis. Materials and methodsThe papers on both 4NQO- and DMBA-induced experimental oral carcinogenesis were published since 1962. All the eligible papers were retrieved on 12 May 2023 from the Scopus database. ResultsThere were 506 and 349 papers on 4NQO- and DMBA-induced experimental oral carcinogenesis with 10,152 and 6306 citations, respectively. The common distinctive keywords such as rat, tongue neoplasms, drinking water, tumor microenvironment, and cyclooxygenase (COX)-2 were identified in the papers on 4NQO; and the common keywords such as hamster, cheek pouch, lipid peroxidation, glutathione, antioxidants, and topical drug administration were identified in the papers on DMBA. Importantly, 105 and 65 potential chemopreventive agents were identified from the papers on 4NQO and DMBA, respectively. Furthermore, 15 promising agents such as COX-2 inhibitor, curcumin, garlic were researched concurrently in both the two animal models. ConclusionThis study for the first time reports the scientometric characteristics of 4NQO- and DMBA-induced experimental oral carcinogenesis. Importantly, we identify a valuable profile for oral cancer chemopreventive agents, which will aid researchers and investigators in studying oral cancer chemoprevention.

Trends on Chlamydomonas reinhardtii growth regimes and bioproducts.

The green microalga Chlamydomonas reinhardtii is a model microorganism for several areas of study. Among the different microalgae species, it presents advantageous characteristics, such as genomes completely sequenced and well-established techniques for genetic transformation. Despite that, C. reinhardtii production is still not easily commercially viable, especially due to the low biomass yield. So far there are no reports of scientometric study focusing only on C. reinhardtii biomass production process. Considering the need for culture optimization, a scientometric research was conducted to analyze the papers that investigated the growth regimes effects in C. reinhardtii cultivation. The search resulted in 130 papers indexed on Web of Science and Scopus platforms from 1969 to December 2022. The quantitative analysis indicated that the photoautotrophic regime was the most employed in the papers. However, when comparing the three growth regimes, the mixotrophic one led to the highest production of biomass, lipids, and heterologous protein. The production of bioproducts was considered the main objective of most of the papers and, among them, biomass was the most frequently investigated. The highest biomass production reported among the papers was 40gL-1 in the heterotrophic growth of a transgenic strain. Other culture conditions were also crucial for C. reinhardtii growth, for instance, temperature and cultivation process.

Mapping the Knowledge Domains of Research on Nanoscale Zero-Valent Iron in Remediation of Contaminated Soil: a Scientometric Study

Mapping the Knowledge Domains of Research on Nanoscale Zero-Valent Iron in Remediation of Contaminated Soil: a Scientometric Study

A scientometrics and visualization analysis of oxidative stress modulator Nrf2 in cancer profiles its characteristics and reveals its association with immune response

BackgroundNrf2, an essential and fascinating transcription factor, enjoys a dual property in the occurrence and development of inflammation and cancer. For over two decades, numerous studies regarding Nrf2 in cancer have been reported, whereas there is still a lack of a scientometrics and visualization analysis of Nrf2 in cancer. Hence, a scientometric study regarding the oxidative stress modulator Nrf2 was implemented. MethodsAfter the quality screening, we defined 7168 relevant studies from 2000 to 2021. CiteSpace, VOSviewer, R software, and GraphPad Prism were used for the following scientometric study and visualization analysis, including field profiles, research hotspots, and future predictions. ResultsThe total number of publications and citations are 1058 and 54,690, respectively. After polynomial fitting curve analysis, two prediction functions of the annual publication number (y = 3.3909x2 - 13585x + 1 E+07) and citation number (185.45x2 - 743669x + 7 E+08) were generated. After scientometric analysis, we found that Biochemistry Molecular Biology correlates with Nrf2 in cancer highly, and Free Radical Biology and Medicine is a good choice for submitting Nrf2-related manuscripts. The current research hotspots of Nrf2 in cancer mainly focus on cancer therapy and its cellular and molecular mechanisms. “antioxidant response element (87.5)", “gene expression (43.98)", “antioxidant responsive element (21.14)", “chemoprevention (20.05)", “carcinogenesis (19.2)", “cancer chemoprevention (18.45)", “free radical (17.15)", “response element (14.17)", and “chemopreventive agent (14.04)" are important for cancer therapy study. In addition, “glutathione-S-transferase (47)", “keap1 (15.39)", and “heme oxygenase 1 gene (24.35)" are important for inflammation and cell fate study. More interestingly, by performing an “InfoMap” algorithm, the thematic map showed that the “immune response” is essential to oxidative stress modulator Nrf2 but not well developed, indicating it deserves further exploration. ConclusionThis study revealed field profiles, research hotspots, and future directions of oxidative stress modulator Nrf2 in inflammation and cancer research, and our findings will offer a vigorous roadmap for further studies in this field.

Analysis of Research Publication on Logistics at the Time of COVID-19: A Scientometric Study

Abstract: Coronaviruses have a wide range of health, mobility, and economic consequences. The Coronavirus pandemic is an unprecedented incident that has drawn the attention of the general public to supply chain management. It caused severe interruptions between 2020 and 2022. Despite the importance and size of the impact of coronaviruses on research performance across time, the literature on comprehensive coronavirus-related research performance is limited. This study aimed at a scientometric evaluation of bibliographic facts associated with the supply chain during the pandemic, and data related to it was extracted from PubMed between January 2020 and December 2022. The purpose of this research is to examine scientometric methods such as frequency distribution, percentage analysis, relative growth rate, doubling time, and degree of collaboration. We have obtained a total of 116 publications during this study period, and a maximum of 26 (22.4%) contributions were made in the months of May to August 2021. The relative growth rate is declining, and the doubling time is increasing between May to August 2021. Scientifically analysing and comprehending bibliographic facts associated with the supply chain during the COVID-19 pandemic as widely as possible can also assist society in being better prepared for future pandemic breakouts, ultimately supporting informed decision-making in light of societal values. The authors highly advocate the recent COVID-19 epidemic as a call for greater collaborative, worldwide research.

Does resveratrol improve cognition in humans? A scientometric study to an in-depth review.

In order to understand the different processes and mechanisms of cognitive function and resveratrol (RES) as an active participant in pathophysiological events that affect cognitive function. First, the Web of Science (core collection) was selected as the data source. To ensure the comprehensiveness and accuracy of the search data, the index was selected as "SCI-EXPANDED", and the search formula was TS = resveratrol AND TS = ("cognitive" OR "memory" OR "cognition" OR "mood"). Next, details of authors, keywords, journals, countries, institutions, references, and more were analyzed by CiteSpace and VOSviewer software. Finally, we explored the mechanism by which RES could improve cognitive impairment, that involves healthy young adults, healthy elderly, post-menopausal women, and diseases involving Alzheimer's disease (AD), diabetes-related cognitive impairment, mental illness, post-stroke cognitive impairment, and neonatal hypoxic-ischemic injury. 287 valid papers were obtained. The scientometric results demonstrated 287 papers used in this study came from 1601 authors from 443 organizations in 38 countries, published in 169 journals, and cited 13,680 literatures from 2431 journals. Depression, AD, cerebral ischemia, diabetic cognitive impairment, and cognitive function in the elderly are all keywords of the co-occurrence network. This study supports the hypothesis that chronic RES intake may positively affect brain function. But it has become challenging to determine the optimal dose, time and duration of RES and improve the bioavailability of RES, which many researchers need to overcome.

A scientometric study of tobacco and alcohol use as risk factors for oral cavity health

Background/purposeTobacco and alcohol are the well-known carcinogenic agents of oral cavity health. The purpose of this study was to investigate the scientometric characteristics of alcohol and tobacco use and oral health. Materials and methodsThe papers on alcohol and tobacco use and oral cavity were published since 1885 and 1895, respectively. All the eligible papers were retrieved on March 20, 2023 from the Scopus database. ResultsThere are 2529 and 1545 papers on tobacco smoking and alcohol drinking and oral cavity in the Scopus database, respectively. Based on the frequency of keywords in all included papers, both smoking and drinking are involved in mouth neoplasms, oral cancer, leukoplakia, and periodontal diseases. In the papers on tobacco and alcohol use and oral cavity, the same research keywords confirm tobacco and alcohol use associate with oral cancer risk possibly through influencing genetics and gene and protein expression. For the distinctive keywords, nicotine, smoking cessation, and electronic cigarette are unique keywords of tobacco use. Acetaldehyde, alcohol dehydrogenase, and alcohol metabolism are unique ones of alcohol use. ConclusionThis study for the first time reports the scientometric characteristics of tobacco and alcohol use and oral health, which might aid healthcare authorities to promote tobacco and alcohol control measures focused on the necessities of their population.

Four Decades of Foot and Ankle Research Activity: A Scientometric study of Subspecialty Foot and Ankle Journals.

To evaluate foot and ankle documents using scientometric methods and provide insight into global research activities. This scientometric study was conducted at the Department of Spine Surgery, Ganzhou People's Hospital, China. Documents on foot and ankle from 1980 to 2019 were retrieved from the Scopus database. The number of documents, year of publication, journal, country, institution, author, h-index, and top-cited documents were analyzed. In total, 11313 documents were retrieved. The annual research output on foot and ankle showed a dramatic increase over the past four decades, especially in the past decade (p = 0.000). Foot & Ankle International published the biggest number of documents (44.48%). The United States contributed more than half (52.17%) of the global production, followed by the United Kingdom (11.39%), and Germany (3.62%). The United States had the highest h-index (109). The Hospital for Special Surgery (1.87%) ranked first in terms of productivity, followed by Union Memorial Hospital (1.37%), and Duke University Medical Center (1.24%). The most productive author was Myerson MS (1.25%), followed by Schon LC (0.77%), and Hyer CF (0.74%). Research on foot and ankle has thrived rapidly over the past four decades, particularly in the last decade. The United States contributes the most to the quantity and quality of foot and ankle documents.

1991 to 2019: The rise of machine interpreting research

Conceived as a scientometric study, this paper searches for understanding the research status of machine interpreting on the IEEE (Institute of Electrical and Electronics Engineers) database from 1991 to 2019. Documents were analyzed considering a series of measures such as most prominent academic institutions and countries that investigate machine interpreting, citation, co-authorship, keywords co-occurrence, reference coupling, and textual-based analysis retrieved from the documents’ titles and abstracts. Through VOSviewer software and its tools for data collecting and visualization, machine interpreting research in the analyzed corpus focuses on three main concerns: machine translation, speech synthesis, and Japanese language.

Scientometric and Bibliographic Analysis of Pedestrian Safety Research

The vulnerability of pedestrians means that pedestrian and vehicle crashes often have severe consequences. Pedestrian safety related research has attracted researchers’ attention since the 1970s and has become increasingly popular in recent years. There were about 250 papers published in 2021 alone on this research domain. However, scientometric studies on a specific safety area are rarely conducted. Scientometric and bibliographic analyses provide researchers with a thorough understanding of research topics and historical knowledge on authorship, publishers, keywords (thematic topics), and collaborations that occurred in the research community on the specific research domain. This study bridges this gap by collecting 2,689 pedestrian safety-related papers from the Web of Science (WoS) Core Collection database and conducting a scientometric and bibliographic analysis. The results show the increasing popularity of pedestrian safety-related studies, and the number of papers has increased significantly each year since 2000. This study also investigated the changes in the research interests in pedestrian safety-related studies temporally. The results show research interests changed from investigating the built environment, theoretical modeling, behavioral studies, and advanced modeling techniques over time. Moreover, the findings suggest that child pedestrian safety interests started to gain popularity in 2008, soon after the Safe Routes to School (SRTS) program was initiated in 2005, which shows the positive interactions between this research domain and policy-making progress.

Visualizing research trends and thematic structure evolution of graphic design

The purpose of this research is to draw a scientific map and show the evolution of thematic structure of world’s graphic design. This is a scientometric study that uses quantitative and indicative methods of network analysis. To draw a scientific map of graphic design research literature, the data was extracted from the Web of Science database within a 2000–20 time period. The retrieved records were formatted using WC10.exe conversion software and then were mapped using Ravar Matrix, Ucinet, Netdraw, VOSviewer software. The findings revealed a growing trend in the number of articles published in graphic design and the most widely used subject areas in the field of graphic were identified. The field of graphic design was mapped based on the closeness centrality measure and its findings revealed that topics such as graphic sign, computer applications, molecular dynamics, computer architecture and graphics processing have the greatest impact on the map.

Pemphigus and pemphigoid research by dermatologists and stomatologists: A scientometric and comparative study

Background/purposePemphigus and pemphigoid are systemic bullous autoimmune diseases affecting skin and/or mucosal membranes with the life-threatening nature, especially pemphigus vulgaris. The papers published by dermatologists and stomatologists preferentially represent their concerns of a mucocutaneous disease. Materials and methodsThe objective of this study was to compare the scientometric characteristics of pemphigus and pemphigoid publications by dermatologists and stomatologists in the Scopus database. ResultsThere are 9276 and 760 papers published by dermatologists and stomatologists, respectively. The annual number of the publications by dermatologists stably raised from 218 to 526 during 2007–2022; while the number by stomatologists raised with a small amount from 18 to 51 during this period. For the most-cited top-200 papers, the total citation count is 42,766 and the h index is 148 for pemphigus publications by dermatologists; whereas the count is 14,689 and h index is 63 for publications by stomatologists. Notably, first signs of pemphigus often appear in oral mucosa, manifesting as erythema, blisters, as well as mouth ulcer, gingivitis, lichen planus-like pemphigus. ConclusionThis study firstly reports the scientometric characteristics of pemphigus publications by dermatologists and stomatologists. The scale and citations of dermatologists' publications greatly outweigh stomatologists’ ones, suggesting stomatologists can learn from and more cooperate with dermatologists regarding pemphigus research.

Mapping the Landscape of Indian Genomics Research: A Scientometric Analysis

This Scientometric study aimed to provide state-of-the-art information on research growth and trends, areas of potential growth and development in genomics in India, and identify the key players (organizations or institutions, and funding agencies). It was found that the number of publications and citations related to genomics research has been steadily increasing over the years, indicating a growing interest and investment in the field as the Indian Council of Agricultural Research was the leading contributor to the field. Among the 159 contributing countries from 2012 to 2021, India contributed 4.46% of publications. The Department of Biotechnology (Ministry of Science and Technology, India) provided the most funds for genomics research. In the last decade, research was primarily focused on "Genetic Diversity," "Polymorphism," "Comparative Genomics," "Phylogeny," " Random amplification of polymorphic DNA (RAPD)," "Single nucleotide polymorphism (SNP)," "Polymerase chain reaction (PCR)," "Gene Expression," etc. The study's findings may shed light on the strengths and weaknesses of the country's research infrastructure, as well as the effectiveness of government policies and funding mechanisms.