Objective To explore the application of case-based discussion combined with translational medicine teaching method in clinical teaching of gastrointestinal surgery.Methods Totally 100 undergraduates of clinical medicine in grade 2007 and 100 undergraduates in grade 2008 from the second military medical university were divided into experimental class (50 students,25 in discussion class and 25 in comprehensive class) and control class (50 students).Method of case-based discussion was applied in discussion class; method of case-based discussion combined with translational medicine was employed in comprehensive class and traditional method was used in control class.Results Scores in experimental class were superior to those in control class ; questionnaire survey showed that 90% students thought the new model was better than the traditional model; the interests of students in exploring clinical problem in experimental class were increased (90% vs.50% ) ;the sense of mission and responsibility was Strengthened (86% vs.64% ) ;the scientific research thinking was more active (80% vs.48% ) ; the individual ability and quality were enhanced (76% vs.50% ),the depth and width of study were markedly increased (80% vs.52% ),the consciousness of independent study and thinking was strengthened (88% vs.54% ).Comprehensive class had more obvious improvements in scientific research thinking,individual ability and quality,depth and width of study,independent study and thinking.Conclusions The new teaching model which combined translational medicine with case discussion breaks through the traditional model and adapts to the requirements of modem medicine,it can enhance the teaching effect and worth promoting in educational reform. Key words: Translational medicine; Case-based discussion; Gastrointestinal surgery; Educational reform
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