The article highlights the scientific and organizational activities of an outstanding scientist, an academician of the Ukrainian Academy of Sciences (UAS) (since 1921, the All-Ukrainian Academy of Sciences (UAS), a corresponding member of the Academy of Sciences of the USSR, a professor at Kyiv University, an organizer of the national science, folk and local studies movement, a specialist in the fields of ethnography, folkloristics, local history and literature of Andrii Myrofanovych Loboda (1871–1931). Some program works of A. Loboda are analyzed, attention is focused on the scientist’s interpretation of the subject of local history, substantiation of its role in the development of various branches of science, the place of the folklore-ethnographic component in local history, and the formulation of tasks faced by ethnologists of the republic. A. Loboda’s significant contribution to the formation of an organized local history movement in the 20s of the XX century is emphasized: insisting on the need to accelerate the development of the local history movement in Ukraine, leading the activities of the Local History Commission (Kyiv Local History Commission) and the Ethnographic Commission of the Ukrainian Academy of Sciences, which became one of the most important folklore and ethnographic centers of Ukraine and played an important role in the development of Ukrainian ethnology. Emphasis is placed on the official publications of the commissions. In addition to highlighting the great scientific organizational, editorial and pedagogical work carried out by A. Loboda at the beginning and in the 20s of the 20th century, the directions of his scientific research during this period are also outlined: new phenomena in folklore and folk life, continuation of research with history of national folkloristics and ethnography, close monitoring of folklore and ethnographic processes not only in Ukraine, but also in other republics of the USSR, prompt response to important publications in the field of folklore and ethnography. The author of the article provides suggestions on the possible use of certain aspects of the experience of those years in modern conditions.