Case studies of the Canada Department of Fisheries and Oceans (DFO), Northwest Atlantic Fisheries Organization (NAFO), and the Food and Agriculture Organization of the United Nations (FAO) highlighted factors influencing scientific communication that are contingent on the characteristics of the many dynamic and iterative science-policy interfaces among decision-makers, scientists, and other stakeholders. Direct observations of 15 scientific and management meetings coupled with interviews with 78 scientists and managers revealed aspects of the information pathways, i.e., production, communication, and use of scientific information in these organizations. Unique features of decision-making and information use enable the production of credible, relevant, and legitimate information in each organization, including trade-offs in these attributes to support fisheries governance objectives. For instance, defined processes for producing scientific advice embedded in fisheries management authorities, such as DFO and NAFO, ensure uptake of information in decision-making. As a boundary organization, FAO bridges science and policy-making groups among its member countries. The demand for scientific advice, policy development, and trade aspects are primary drivers in the information pathways. However, organizational aspects such as dispersed units and inadequate communication persist as barriers to information flow. Across the geographic scales of the three organizations, stakeholders apart from government scientists and policy-makers, e.g., the fishing industry, non-governmental organizations (NGOs), and the public, are increasingly involved in the information pathways. Insights about the information pathways can equip the organizations to evaluate or modify practices to increase the uptake of information in decision-making as fisheries management issues and considerations become more complex.