The emphasis of science education is to increase students science literacy through investigative measures that include planning, measuring, observing, analyzing data, developing and evaluating procedures, and studying evidence based on the introduction of modern learning technologies (STEM-technologies). The article considers the concept of science as a pioneer of «science education», substantiates the theoretical and methodological fundamentalization of science education on the basis of STEM-education of a technical institution of higher education. It is determined that the main function of the system of science education is to provide society with scienceally literate citizens. The information and resources (usually financial) reinforce this system. In the article we have formed a model of science on the development of STEM-educational trends of innovative development of education in Ukraine. We have formed the features of science education on the basis of STEM-technologies that will contribute to the introduction of modern methods of teaching physics and professionally oriented disciplines. The integration processes in education in recent years have become increasingly important, as they are aimed at implementing new educational ideals – the formation of a holistic system of knowledge and skills of the individual, the development of their creative abilities and potential. The idea of integrated teaching of physics and professionally oriented disciplines is relevant, because its successful methodological implementation involves achieving the goal of quality science education, ie competitive education, able to ensure each person to achieve a life goal, creative self-affirmation in various social spheres. Learning science will allow students to lead a full and responsible life, encouraging them to learn independently, solve new situations, think critically, think creatively, make informed decisions and solve problems. Students should also develop an understanding of the relationship between science, technology, society and the environment (STSE), and strengthen the ability to integrate and apply knowledge and skills in physics and vocational disciplines in technical freelance education. They must be able to address changes and challenges in a constantly evolving society and contribute to the science and technological world.