Access to menstrual hygiene products is a major challenge facing women and girls in developing countries, including Kenya. This study is about the socioeconomic determinants of menstrual management among girls in Nyatike Sub County. The study was guided by the following specific objectives: to establish the effects of traditional practices on menstrual management among primary school girls, examine the effects of knowledge and awareness of hygiene on menstrual management, analyze the effects of family income on the menstrual management of girls, and assess the current measures that are in place to enhance menstrual health management of girls in rural primary schools in Nyatike Sub County. A descriptive survey design was used, and cluster sampling coupled with simple random sampling was used to select 689 respondents for the questionnaire, who were mainly primary school girls, head teachers and teachers, and the female heads of households. Descriptive analysis showed that 59.3% of the girls have encountered traditional restrictions during their menstruation. About 74.4% of the respondents believe that knowledge about menstrual hygiene has improved their overall confidence and comfort during menstruation. Additionally, 53.2% of the girls always have access to the menstrual hygiene products they need. However, 46.8% still have difficulties obtaining the necessary products. Consequently, 76.8% of the respondents revealed that their schools are sensitizing students about menstrual health and hygiene. The inferential analysis showed that traditional practices have various effects on menstrual management among primary school girls. In conclusion, there is a positive effect of knowledge and awareness of hygiene on menstrual management among primary school girls. It is also clear that most primary schools have implemented some menstrual health management strategies for girls. The study recommends regular awareness and sensitization programs for students, teachers, parents, and the community to eliminate stigma, myths, and misconceptions around menstruation.