In the contemporary landscape of digital healthcare, the confidentiality and integrity of medical images have become paramount concerns, necessitating the development of robust security measures. This research endeavors to address these concerns by proposing an innovative image encryption scheme tailored specifically for enhancing medical image security. The proposed scheme integrates a sophisticated blend of symmetric and asymmetric encryption techniques, complemented by a novel key management system, to fortify the protection of medical image data against unauthorized access and malicious tampering. The proposed DNA-based encryption algorithm leverages the unique properties of DNA encoding to securely scramble image data, providing an added layer of protection. By utilizing DNA sequences in the encryption and decryption processes, the scheme achieves a high level of data confusion and diffusion, significantly enhancing security. The efficacy of the proposed encryption scheme is validated through comprehensive experimental evaluations, which demonstrate its proficiency in ensuring data security while maintaining computational efficiency. The scheme's compatibility with existing medical imaging systems is also examined, affirming its seamless integration into contemporary healthcare infrastructures. This research contributes to the advancement of medical image security by proposing an efficient encryption scheme that strikes a balance between stringent security requirements and practical implementation considerations. The primary contributions include the development of a DNA-based encryption algorithm and a novel key management system, both of which significantly enhance the security of medical images. This research contributes to the advancement of medical image security by proposing an efficient encryption scheme that strikes a balance between stringent security requirements and practical implementation considerations. By safeguarding the confidentiality and integrity of medical images, the proposed scheme empowers healthcare providers to uphold patient privacy and trust in the digital age. Experimental results show that this approach ensures robust encryption without compromising image quality, making it suitable for sensitive medical imaging applications.