Scanning UV Research Articles

Preparation and characterization of antibacterial, antioxidant, and biocompatible p-coumaric acid modified quaternized chitosan nanoparticles

To fabricate multifunctional nanoparticles (NPs) based on chitosan (CS) derivative, we first prepared quaternized CS (2-hydroxypropyltrimethyl ammonium chloride CS, HTCC) via a one-step approach, then synthesized p-coumaric acid (p-CA) modified HTCC (HTCC-CA) for the first time through amide reaction, and finally fabricated a series of NPs (HTCC-CA NPs) using HTCC-CAs with different substitution degrees and sodium tripolyphosphate (TPP) by ionic gelation. Newly-prepared HTCC and HTCC-CAs were characterized by FT-IR, 1H NMR, elemental analysis (EA), full-wavelength UV scanning, silver nitrate titration, and Folin-Ciocalteu methods. DLS and TEM results demonstrated that three selected HTCC-CA NPs had moderate size (< 350 nm), good dispersion (PDI < 0.4), and positive zeta potential (11–20 mV). The HTCC-CA NPs had high antibacterial activity against six bacterial strains, and the minimum inhibitory concentration (MIC) values were almost the same as the minimum bactericidal concentration (MBC) values (250–1000 μg/mL). Also, the HTCC-CA NPs had good antioxidation (radical scavenging ratio > 65 %) and low cytotoxicity (relative cell viability >80 %) to the tested cells. Totally, HTCC-CA NPs with high antibacterial activity, great antioxidation, and low cytotoxicity might serve as new biomedical materials for promoting skin wound healing.

Scaling-Up Seeded Hydrothermal Nanowire Synthesis on Non-planar Surfaces Using a Flow Reactor

While many nanomaterial synthesis processes have been demonstrated at the laboratory scale, grand challenges remain at the nanomanufacturing frontier, where it is necessary to maintain tunable material structure and properties at large length scales using high-throughput, low-cost, and sustainable processes. Seeded hydrothermal synthesis is widely used to generate tunable nanostructures with controlled geometric parameters. In this study, we used atomic layer deposition to deposit precise and conformal seed layers which were subsequently processed using a customized hydrothermal flow reactor. The reactor design allows for control of the solution temperature profile in space and time, as well as the solution flow profile. Recirculation of the hydrothermal growth solution enables reduction of the chemical waste by 77–92% compared to a single pass flow reactor. This “surface-directed assembly” process allows for the growth of vertically aligned zinc oxide (ZnO) nanowires (NWs) directly onto macroscopic (cm-scale) non-planar surfaces. We quantify the uniformity of the NW morphology using scanning electron microscopy and UV absorption measurements. The NWs were further functionalized to form superhydrophobic and optically transparent surface coatings along a curved glass dome substrate. The surface coatings were shown to significantly reduce the rate of biofouling from marine algae by ∼75%. This demonstrates a pathway for the scale-up of hydrothermal synthesis processes with a variety of applications in the biological and environmental fields, including medical devices and optical and oceanographic sensors.

Facile preparation of porphyrin@g-C3N4/Ag nanocomposite for improved photocatalytic degradation of organic dyes in aqueous solution

In the quest of improving the photocatalytic efficiency of photocatalysts, the combination of two and more semiconductors recently has garnered significant attention among scientists in the field. The doping of conductive metals is also an effective pathway to improve photocatalytic performance by avoiding electron/hole pair recombination and enhancing photon energy absorption. This work presented a design and fabrication of porphyrin@g-C3N4/Ag nanocomposite using acid-base neutralization-induced self-assembly approach from monomeric porphyrin and g-C3N4/Ag material. g-C3N4/Ag material was synthesized by a green reductant of Cleistocalyx operculatus leaf extract. Electron scanning microscopy (SEM), X-ray diffraction (XRD), FT-IR spectroscopy, and UV–vis spectrometer were utilized to analyse the properties of the prepared materials. The prepared porphyrin@g-C3N4/Ag nanocomposite showed well integration of porphyrin nanostructures on the g-C3N4/Ag's surface, in which porphyrin nanofiber was of the diameter in nanoscales and the length of several micrometers, and Ag NPs had an average particle size of less than 20 nm. The photocatalytic behavior of the resultant nanocomposite was tested for the degradation of Rhodamine B dye, which exhibited a remarkable RhB photodegrading percentage. The possible mechanism for photocatalysis of the porphyrin@g-C3N4/Ag nanocomposite toward Rhodamine B dye was also proposed and discussed.

Ruthenium biochanin-A complex ameliorates lung carcinoma through the downregulation of the TGF-β/PPARγ/PI3K/TNF-α pathway in association with caspase-3-mediated apoptosis.

Lung cancer is the most often reported cancer with a terrible prognosis worldwide. Flavonoid metal complexes have exhibited potential chemotherapeutic effects with substantially low adverse effects. This study investigated the chemotherapeutic effect of the ruthenium biochanin-A complex on lung carcinoma in both in vitro and in vivo model systems. The synthesized organometallic complex was characterized via UV‒visible spectroscopy, FTIR, mass spectrometry, and scanning electron microscopy. Moreover, the DNA binding activity of the complex was determined. The in vitro chemotherapeutic assessment was performed on the A549 cell line through MTT assay, flow cytometry, and western blot analysis. An in vivo toxicity study was performed to determine the chemotherapeutic dose of the complex, and subsequently, chemotherapeutic activity was assessed in benzo-α-pyrene-induced lung cancer mouse model by evaluating the histopathology, immunohistochemistry, and TUNEL assays. The IC50 value of the complex in A549 cells was found to be 20 µM. The complex demonstrated significant apoptosis induction, enhanced caspase-3 expression and cell cycle arrest with downregulated PI3K, PPARγ, TGF-β, and TNF-α expression in A549 cells. The in vivo study suggested that ruthenium biochanin-A therapy restored the morphological architecture of lung tissue in a benzo-α-pyrene-induced lung cancer model and inhibited the expression of Bcl2. Additionally, increased apoptotic events were identified with upregulation of caspase-3 and p53 expression. In conclusion, the ruthenium biochanin-A complex successfully amelioratedlung cancer incidence in both in vitro and in vivo models through the alteration of the TGF-β/PPARγ/PI3K/TNF-α axis with the induction of the p53/caspase-3-mediated apoptotic pathway.

Ecofriendly Chromatographic Assay of Metformin Combinations; Content Uniformity Tests and Toxicity Profiling.

Accurate, sensitive and green HPTLC chromatographic method was proposed for simultaneous determination of metformin, glipizide and sitagliptin in the presence of metformin potential toxic impurities melamine and cyanoguanidine. The separation was completed on silica gel HPTLC F254 plates using a mixture of ethyl acetate: methanol: ammonia: formic acid (7: 2: 0.2: 0.2, by volume) as a developing system with UV scanning for the developed bands at 235nm. The Rf values for metformin, glipizide, sitagliptin, melamine and cyanoguanidine were 0.17, 0.84, 0.67, 0.47 and 0.75, respectively. Linear responses were observed in the ranges of 0.2-3, 0.07-1.5, 1.5-5, 0.8-4 and 0.4-2μg/band with correlation coefficients of 0.9999, 0.9998, 0.9997, 0.9996 and 0.9998 for metformin, glipizide, sitagliptin, melamine and cyanoguanidine, respectively. The proposed method was validated as per ICH criteria with respect to linearity, accuracy, precision, specificity and robustness. The validated method was successfully applied for determination of the studied drugs in Janumet® and Engilor® tablets; also, the results were statistically compared to those obtained by the reported spectrophotometric method and no significant difference was found between them. This method permitted the accurate simultaneous determination of the studied drugs, indicating its ability to be used for routine quality control assays of these drugs.

Photoelectrocatalytic Degradation of Methylene Blue on Electrodeposited Bismuth Ferrite Perovskite Films.

Electrodeposited bismuth ferrite (BiFeO3) thin films on fluorine-doped tin oxide (FTO) substrate were employed as photoanodes in the photoelectrocatalytic degradation of methylene blue. The BiFeO3 thin films electrodeposited for 300 s, 600 s, 1200 s, 1800 s and 3600 s were characterised with XRD, field emission scanning electron microscopy (FESEM) and UV-vis diffuse reflectance spectroscopy. SEM images displayed different morphology at different electrodeposition times which affects the photoelectrocatalytic (PEC) performances. The FESEM cross-sectional area was used to measure the thickness of the film. The optical properties showed that the band gaps of the photoanodes were increasing as the electrodeposition time increased. The photocurrent response obtained showed that all thin film photoanodes responded to visible light and lower charge transfer resistance (from electrochemical impedance spectroscopy studies) was observed with photoanodes electrodeposited at a shorter time compared to those at a longer time. The PEC application of the photoanode for the removal of methylene blue (MB) dye in water showed that the percentage degradation decreased with an increase in electrodeposition time with removal rates of 97.6% and 70% observed in 300 s and 3600 s electrodeposition time, respectively. The extent of mineralisation was measured by total organic carbon and reusability studies were carried out. Control experiments such as adsorption, photolysis, photocatalysis and electrocatalysis processes were also investigated in comparison with PEC. The electrodeposition approach with citric acid exhibited improved electrode stability while mitigating the problem of catalyst leaching or peeling off during the PEC process.

Methylammonium lead triiodide perovskite-based solar cells efficiency: Insight from experimental and simulation

This work deals with the growth investigation of the methylammonium lead triiodide (MAPbI3) thin films prepared by the spin coating technique.Firstly, MAPbI3 films were studied by X-ray diffraction (XRD) and scanning electron microscopy (SEM) and UV–Visible spectroscopy as well as photoluminescence techniques are used to calculate the band gap energy. Indeed, the high-quality MAPbI3 perovskite films were obtained by using Chlorobenzene as an antisolvent with good crystallinity, large grain sizes, and higher absorption compared to MAPbI3 treated by toluene. Secondly, the performance of FTO/TiO2/MAPbI3/Spiro OMeTAD/Au perovskite solar cell was evaluated using a numerical simulation of the Solar Cell by SCAPS simulator. The effect of the structural and physical parameters of MAPbI3 absorber layer and HTL with the different antisolvents, including thickness, defect density, total charge density, donor density and electron affinity. Obtained results are: Jsc of 25.96 mA/cm2, PCE of 30.70%, Voc of 1.259 V, FF of 88.93% of MAPbI3-based solar cells when MAPbI3 is treated by toluene. However, for MAPbI3- Chlorobenzene, the I–V characteristics are rather: Jsc of 28.18 mA/cm2, PCE of 31.81%, FF of 88.19% and Voc of 1.200 V. It is pointed out that the use of chlorobenzene may be of interest to improve the perovskites solar cells performances.

Photo-electrochemical water splitting and electrochemical performance of silicon nanowire arrays

Silicon nanowires (SiNWs) were prepared using n-Si(100) by a simple two-step metal-assisted chemical etching (MACE) approach with different durations of 15 and 30 min. Surface morphology, structural, and optical properties of prepared SiNWs were investigated using Scanning Electron Microscope (SEM), x-ray diffraction (XRD) and UV–vis absorption, respectively. Under visible light, a photoelectrochemical cell (PEC) was used to measure the properties of a photoanode device that was fabricated based on n-SiNWs for splitting water. At 0.78 V, the SiNWs that were prepared in 30 min had a photocurrent density of 3.72 mA.cm−2 and a photoconversion efficiency (η) of 1.37%. Cyclic voltammetry (CV) measurements showed that both the n-Si(100) wafer and the n-SiNWs that were made with etching times of 15 and 30 min showed faradaic behavior with redox peaks. Electrochemical impedance spectroscopy (EIS) showed that the SiNWs photoanode prepared with 30 min of etching time had a charge transfer resistance of 3112.3. This is low enough to make it easy for charge to move across the interface. The Mott-Schottky (M-S) analysis revealed a high concentration of carriers of 4.77 × 1021 cm−3 at the working electrode/electrolyte interface,

Synthesis of Zinc Sulfide Nanoparticles Using Pyridinium Ionic Liquids

Zinc sulfide nanoparticles (quantum dots) were synthesized from aqueous solutions of sodium sulfide and zinc sulfate using pyridinium ionic liquids. The average sizes of zinc sulfide nanoparticles were determined by UV spectroscopy, X-ray diffraction, probe and scanning electron microscopy. The influence of the structure and concentration of pyridinium ionic liquids with the tetrafluoroborate anion of the same name on the size of zinc sulfide nanoparticles has been studied. The effect of the precursor concentration on the size of the nanoparticles formed in the ash was established.

Construction of lipid raft-coupled agarose gels as bioaffinity chromatography materials and validation with tropomyosin-related kinase A-targeted drugs

In order to improve the separation process of affinity chromatography that has silica as the main carrier material, we sought to construct Lipid Rafts@CNBr-Sepharose 4B affinity chromatography model. We extracted the lipid rafts from U251 cells with a descaler method and sucrose density gradient centrifugation. Afterwards, it was discovered via immunofluorescence that the lipid rafts contain a large amount of tropomyosin-related kinase A (TrkA) protein. Also, agarose powder in the lyophilised state was pretreated, before the lipid rafts were coupled to the agarose gel in a coupling buffer of alkaline pH. CNBr-Sepharose 4B affinity gel packing was characterised using UV spectrophotometric, immunofluorescence and scanning electron microscopic techniques, wherein and the results showed that the lipid rafts were successfully coupled to the agarose gels. Three compounds were used to verify the specific sorption of Sepharose 4B and CNBr-Sepharose 4B, which showed no specific sorption on the materials. Of note, the prepared Lipid Rafts@CNBr-Sepharose 4B agarose gels packed with TrkA-rich target proteins could be successfully validated for the active drug gefitinib with high affinity sorption efficiency and eluted with good recovery and reproducibility. This study broadens the range of affinity chromatography carrier materials and provides a reference for research in active drug screening.

Electrical and optical properties of electro chemical luminescence device with quasi solid electrolyte and ZnO/TiO2 electrode

In this work, a quasi-solid electrolyte process that can be simply manufactured for an electrochemical luminescence (ECL) device with a ZnO/TiO2 electrode was proposed, and the electro-optical characteristics of the fabricated ECL cells were investigated. The electrolyte was prepared by adding poly (vinylidene fluoride-co-hexa-fluoropropylen) with the Ru(bpy)3(PF6)2 as a luminescence material in 1:4 weigh ratio in 1 g of Acetonitrile (ACN). The ZnO/TiO2 films as an electrode were prepared by RF sputtering system. The ZnO and TiO2 targets were set up in co-sputtered system and FTO glass size 2 × 2 cm2 was used as a substrate. Argon gas flow rating as the working gas was fixed at 30 sccm. First, the ZnO layer is deposited on the FTO substrate at 100 W of RF power and at 10 mTorr of Argon gas pressure. TiO2 layer is deposited on the ZnO layer while increasing the sputtering time by 10 min. The morphological and optical properties of the thin films as electrode were confirmed using scanning electron microscope (SEM, Hitachi Su70), X-ray diffraction (XRD, Rigaku D/max 2100H) and UV–vis spectrometer (DH-2000-BAL Ocean Optics). The performance of proposed ECL devices were evaluated by varying operation voltage of 0.5 V from 2 V to 5 V. As the result, we can achieve high performance of device having a wide operating voltage margin and improved luminance intensity.

Expeditive Chromatographic Methods for Quantification of Solifenacin Succinate along with its Official Impurity as the Possible Acid Degradation Product.

Two selective stability-indicating procedures were adopted for the quantification of Solifenacin succinate (SOL) along with its acid degradant, in its powder form or in pharmaceutical tablet. Under stress conditions, the acid degradation pathway of SOL was investigated, its official impurity (SOL imp-A) was obtained as the possible acid degradation product, also. A densitometric technique based on the separation of SOL from SOL imp-A employing HPTLC plates prelaminated with silica gel 60F254 as the stationary phase and a developing solution containing methanol:chloroform:ammonia (8:1:1, v/v/v) and UV scanning of the developed bands at 220nm. Linear regression analysis data for the calibration plot of SOL showed perfect linear relationships throughout the range of concentration 10-60μg/band. A reversed phase C18 analytical column (4.6 × 250mm, 5μm) was also used to separate the mixture at a flow rate of 1mL/min, using acetonitrile:0.05M phosphate buffer (70:30, v/v) as the mobile phase and phosphoric acid to set pH = 3.5. Quantification was obtained at 220nm using peak area and linear calibration curve across a concentration range of 10-70μg/mL. The recommended procedures were applied to the existing dosage form, and they generated satisfactory results.

Solar photocatalytic performance of glass substrates coated with Ag3PO4 thin films

Silver-orthophosphate (Ag3PO4) photocatalysts exhibit excellent photo-oxidative capabilities under visible light irradiation, especially in their powders form. However, Ag3PO4 in the form of thin films has not been explored that much and very little is known about their performance under solar irradiation. In the present study, glass substrates were coated with Cu-doped Ag3PO4 (Cu-Ag3PO4) and Ag3PO4 thin films using successive ionic layer adsorption and reaction (SILAR) due to its simplicity, relatively low-cost and ability to be performed at low temperatures with low time requirements. The as-deposited thin films were characterized by X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM) and UV–Visible spectrophotometry, while their photocatalytic performances were evaluated on Rhodamine-B (Rh-B) dye degradation under real solar light irradiation. The adopted coating protocol resulted in regular thin films that crystallize in the desired P4̅3n cubic phase, where doping with Cu was shown to be responsible of a crystallite size reduction within the film. From the optical point of view, a broad absorbance in the entire visible range was obtained with bandgap energies of about 2.2 eV in the case of Ag3PO4 thin films, and around 1.65 eV in the case of Cu-Ag3PO4 thin films. Such optical features were exploited to test the photocatalytic performance in the degradation of Rh-B dye. After 4 h of solar irradiation, the variation of the relative concentration of Rh-B solution relative to the degradation efficiency of the photocatalysts was of 54% in the case of Cu-Ag3PO4 thin films and of 89% in the case of Ag3PO4 thin films. So, exploration of a wide area of the solar visible spectrum is made possible under doping, a finding that would improve the overall photocatalytic activity which is very promising for the degradation of other organic pollutants under solar irradiation.

Effect of KOH Concentration on the Optical and Structural Properties of Perovskite CaZnO3 Thin films

A scanning electron microscope, X-ray spectrum, and UV spectrometer have been used in the examination of CaZnO3 perovskite thin films. Chemical Spry Pyrolysis (CSPD) technique was used in the preparation of the films from a mixture including different concentrations of KOH and a constant substrate temperature. The effect of KOH concentration was clear on the film’s transmittance, absorbance, and energy gap. The energy gap varied from 2.75 eV with 0.6 gm of KOH, up to 2.95 eV for 1.2 concentration, and finally, the energy gap became 3.1eV with 1.8 gm of KOH. In addition, the average grain size also decreased with KOH concentration, from 116 nm to 92 nm.

Enhanced The Properties of ZnO Thin Film by Graphene Oxide for Dye Sensitized Solar Cell Applications

In this present work, the effects of coating of graphene oxide (GO) at different concentrations (0, 0.2, 0.3, 0.4, 0.5, and 0.6 mg/ml) onto zinc oxide (ZnO) nanostructured were investigated. ZnO and ZnO coated with GO (ZnO/GO) were prepared using immersion method. The structural, morphology and optical properties of all samples have been studied using x-ray diffraction (XRD), field emission scanning microscopy (FESEM) and UV Vis spectroscopy. The peak obtained from the XRD pattern shows that all samples are in the hexagonal-wurtzite structure. The (002) peak shows the strongest intensity for all samples with the highest (002) peak obtained for the ZnO/GO sample coated at a GO concentration of 0.5 mg/ml. The diameter of ZnO/GO nanostructured samples decreased after coating with GO at concentrations of 0.2 to 0.5 mg/ml and the diameter increased again when ZnO nanostructures were coated with GO at above 0.5 mg/ml. The highest transmission spectrum was obtained for the ZnO/GO sample coated with GO at a concentration of 0.5 mg/ml. In conclusion, the effect of GO coating on ZnO nanostructured can be changed at different concentrations of GO. The optimal properties of ZnO/GO may be suitable as a photoanode in DSSC applications.

Phase transition behavior of pentylcyanobiphenyl liquid crystal containing n-dodecyl-2-hydroxy-1-naphthaldimine

The present work focuses on the phase transition behavior of a thermotropic liquid crystal incorporating a Schiff base having a terminal alkyl chain of 12 carbons, such as, n-dodecyl-2-hydroxy-1-naphthaldimine (SB). Given its interesting molecular structure, the SB was chosen as doping agent for a liquid crystal of cyano-biphenyl type, such as, 4-cyano-4′-n-pentyl-biphenyl (5CB). The study of the guest–host systems, at different concentrations of the solute, was performed using differential scanning calorimetry and UV–visible spectroscopy, equipped with the hot compartment. The fusion and the nematic – isotropic transition temperatures as well as the enthalpies ΔH 0 and entropies ΔS 0 variations of the 5CB-based systems were determined from their spectral data. The thermal properties and orientational order parameters were also determined for the pure and SB doped 5CB, as well as the activation energy for the guest system. The filamentary texture was observed by polarized light optical microscopy for both the pure and Schiff base-doped 5CB.

Bactericidal Effect and Associated Properties of Non-Electrolytic Hypochlorite Water on Foodborne Pathogenic Bacteria.

This study investigated the broad-spectrum bactericidal activity of non-electrolytic hypochlorite water (NEHW) and detected its hydroxyl radical content compared with that of slightly acidic electrolytic water (SAEW). Based on the results of UV scanning and storage stability, higher hypochlorite content and stronger oxidation were found to be responsible for the stronger bactericidal effect of NEHW. NEHW can achieve 99% bacterial disinfection effect by treating with 10 mg/L available chlorine concentration for more than 5 minutes. At the same time, the storage stability of NEHW was higher than that of SAEW. After 20 days of storage under sealed and dark conditions, the pH value only increased by 7.9%, and the effective chlorine concentration remained nearly 80%. The results showed that NEHW had higher germicidal efficacy and storage stability than SAEW.

Synthesis and characterisation of Nickel oxide nanoparticles using CTAB as capping agent

This report presents the synthesis of nickel oxide nanoparticles by hydrothermal route in the presence of sodium hydroxide (NaOH) with Cetyl Trimethyl Ammonium Bromide (CTAB) used as capping agent. Nickel oxide (NiO) being a p- type semiconductor,has wide bandgap and is eco-friendly, low cost and stable material that can serve as promising material for a counter electrode in the DSSC (Dye-Sensitized Solar Cells). The use of capping agent is to control the size of nanoparticles and also prohibit the agglomeration of the synthesized material. The as synthesized nickel oxide nanoparticles (NPs) were analysed using X-ray diffraction (XRD) technique, Field Emission Scanning electron microscope (FESEM) and UV visible spectroscopy. The face-centred cubic (fcc) structure of NiO is revealed by XRD pattern. Surface morphological features associated with nickel oxide were studied by using FESEM. UV–vis spectroscopy is done to evaluate the band gap of as-synthesized material which is found to be around 2.81 eV.

In vitro effects of the green synthesized silver and nickel oxide nanoparticles on the motility and egg hatching ability of Marshallagia marshalli

BackgroundGastrointestinal nematodes are one of the serious health problems on the human society and in the livestock industry. Marshallagia marshalli is one of the most prevalent gastrointestinal nematodes in small ruminant, have subtle but more significant adverse effects on the health and fitness of their hosts.AimIn this study, green synthesized nickel oxide (NiO) and silver (Ag) nanoparticles (NPs) have been checked to evaluate the possible antiparasitic effects of nickel oxide and silver nanoparticles on Marshallagia marshalli.MethodsThe characterization of synthesized NiO NPs and Ag NPs was confirmed using the scanning electron microscopy (SEM), X-Ray diffraction (XRD), and UV–Visible spectroscopy. The adult worms were incubated with various concentrations of NiO and Ag NPs with the quantity of; 1, 2, 4, 8, 12, and 16 ppm for 24 h. Mobility and egg hatching abilities of the parasites were recorded at 4-h intervals.ResultsThe results showed that both of the nanoparticles NiO and Ag NPs have anthelmintic activity against Marshallagia marshalli. The anthelmintic effects increased with an increase in the concentration of nanoparticles and the incubation time.ConclusionThe outcome data concluded that Ag-NPs possess a higher level of efficacy than NiO NPs.

Auto combustion synthesis of ZnO for degradation of organic dye under natural solar light with bactericidal activity

• ZnO nanoparticles synthesized by facile autocombustion method. • ZnO nanoparticles efficiently degrade Methylene Blue dye under sunlight irradiation. • ZnO nanoparticles exhibit significant anti-bacterial activity for gram-negative and gram-positive bacterial strains. • Mechanism of photocatalysis was studied. Here we report synthesis of natural sunlight active zinc oxide (ZnO) nanoparticles by facile solution auto combustion method using citric acid as a fuel. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), High resolution transmission electron microscopy (HRTEM), Energy-dispersive X-ray spectroscopy (EDAX), Field emission scanning electron microscopy (FESEM) and UV–Visible spectrophotometric analysis (UV–Vis) were used for study of the structural and optical characteristics of prepared nanoparticles. The breakdown of methylene blue (MB) dye in the presence of sunlight was used evaluating photodegradation activity. The maximum degradation of 98 percent was obtained after 45 min of irradiation by sunlight in basic pH of the MB. Furthermore, the antimicrobial properties were inspected against bacterial pathogens that infect humans, such as gram-negative P. vulgaris , E. coli and gram-positive K. pneumonia, S. aureus by well diffusion method.