Background: Various surgical techniques can be done for depigmentation but recurrence is the limiting factor for many surgical procedures, and the aim of the present study was to evaluate quantitatively the rate of repigmentation postoperatively after using scalpel and diode lasers for depigmentation. Materials and Methods: A total of 20 systemically healthy patients of 18 males and two females, within the age group of 18-40 years with an esthetic complaint of hyperpigmented gingiva were enrolled in this study. The patients were briefed about the surgical procedure and obtained the informed consent; they were randomly divided into two groups. Group A: 10 patients - depigmentation with scalpel technique. Group B: 10 patients - depigmentation with diode lasers (Biolase; ) and followed for 6 months. Results: The results of this study had shown that there is a statistically significant difference in the pre- and post-operative values in scalpel surgical technique with a (P = 0.005), and there is no statistically significant (P = 0.20) difference in the diode laser technique. Statistical Analysis Used: Wilcoxon Signed rank test and Mann-Whitney test. Conclusion: By using diode lasers, the rate of repigmentation is higher than scalpel method; however, it has been documented that there is minimal postoperative bleeding, pain, wound healing, discomfort, and ease of the procedure with diode laser and finally, each technique has its own advantages and disadvantages.
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