ABSTRACT We have obtained the first constraint of the parameter space of Scalar–Tensor–Vector Gravity using the motion of the S2-star around the supermassive black hole at the centre of the Milky Way, and we did not find any serious tension with General Relativity. We used the Schwarzschild-like metric of Scalar–Tensor–Vector Gravity to predict the orbital motion of S2-star, and to compare it with the publicly available astrometric data, which include 145 measurements of the positions, 44 measurements of the radial velocities of S2-star along its orbit, and only the inferred rate of precession, as the latest GRAVITY data are not yet public. We employed a Markov chain Monte Carlo algorithm to explore the parameter space, and constrained the only one additional parameter of Scalar–Tensor–Vector Gravity to α ≲ 0.662 at 99.7 ${{\ \rm per\ cent}}$ confidence level, where α = 0 reduces this modified theory of gravity to General Relativity.