The paper describes the epidemiological characteristics of scabies infestations in the Belgrade in the period 2004-2013. years. The study was performed descriptive epidemiological study. In analyzing the data, the crude an age-specific and standardized incidence rates were used. The standardization is carried out by the direct method, using the world population as a standard. According to the annual report regarding the work in the prevention, combating and elimination of infectious diseases, in the past decade a total 8.013 persons have been affected by scabies. The highest average age-specific incidence rates for scabies were registered in the age group 5-9 years and amounted to 137.60 per 100,000 inhabitants. Peak occurrence of scabies was from October to November (25.57%). The average standardized incidence rate for scabies was 72.02 per 100,000 inhabitants. In the period 2004-2013. in Belgrade registered 14 outbreaks of scabies in which infested 186 persons, and most outbreaks have been registered as a family (28.58%). The observed trend of increasing infestation of scabies points to the necessity of active search for unreported or unrecognized infected person in a family or as a collective and timely prophylactic treatment of contacts.