Introduction: Occupational stress among teachers results from the working conditions. Stressed out teachers cannot work effectively. Their motivation and job satisfaction are lower, and they exhibit undesirable behaviours.Aim: This study aims to find out school teachers' degree of job satisfaction and occupational stress, to identify correlation between work-related stress, job satisfaction, and association between occupational stress with the selected sociodemographic aspects.Method: In order to ascertain occupational stress and job satisfaction among school teachers in the contemporary, demanding world, the researcher carried out a descriptive survey research on assessment of occupational stress and job satisfaction among teachers in selected higher secondary schools of Murshidabad, West Bengal. The method of non-probability convenience sampling was used to choose 120 school teachers working in selected higher secondary schools of Murshidabad, West Bengal. A semi-structured questionnaire, the Teachers Occupational Stress Scale designed by Sajid Jamal and Abdul Raheem, and the Job Satisfaction Survey created by Paul E. Spector, were used to gather the data.Result: The study result showed that majority of school teachers (92.5%) had moderate/average degree of occupational stress. Most of the school teachers (81.66%) had ambivalent level of job satisfaction. The study also revealed occupational stress and job satisfaction of school teachers’ have a weakly negative correlation which was significant. A chi-square test indicated a significant association between the age of a school teacher and occupational stress. The study has implications for Nursing Research, Nursing Administration, Nursing Practice, and Nursing education and it is recommended for future research study.