Abstract In this paper, the global distribution of cloud water based on International Satellite Cloud Climatology Project (ISCCP), Moderate Resolution Imaging Spectroradiometer (MODIS), CloudSat Cloud Profiling Radar (CPR), European Center for Medium-Range Weather Forecasts Interim Re-Analysis (ERA-Interim), and Climate Forecast System Reanalysis (CFSR) datasets is presented, and the variability of cloud water from ISCCP, the Special Sensor Microwave Imager (SSM/I), ERA-Interim, and CFSR data over the time period of 1995 through 2009 is discussed. The results show noticeable differences in cloud water over land and over ocean, as well as latitudinal variations. Large values of cloud water are mainly distributed over the North Pacific and Atlantic Oceans, eastern ITCZ, regions off the west coast of the continents as well as tropical rain forest. Cloud water path (CWP), liquid water path (LWP), and ice water path (IWP) from these datasets show a relatively good agreement in distributions and zonal means. The results of trend analyzing show an increasing trend in CWP, and also a significant increasing trend of LWP can be found in the dataset of ISCCP, ERA-Interim, and CFSR over the ocean. Besides the long-term variation trend, rises of cloud water are found when temperature and water vapor exhibit a positive anomaly. EOF analyses are also applied to the anomalies of cloud water, the first dominate mode of CWP and IWP are similar, and a phase change can be found in the LWP time coefficient around 1999 in ISCCP and CFSR and around 2002 in ERA-Interim.