Two different theoretical approaches to the explanation of individual differences in appraisal of environmental demands are expressed by the trait-anxiety (A-trait) scale of the State-Trait Anxiety Inventory (4) and by Antonovsky's (2) measure of the sense of coherence. Spielberger, whose orientation is a pathogenic one, is concerned primarily with people who feel threatened by environmental demands. Antonovsky, with a salutogenic approach, is interested in those individuals whose world view leads them to perceive demands as challenging. The hypothesis tested in this study and derived from these two orientations, as distinguished by Antonovsky (I), is that people who score high on sense of coherence will score low on A-trait. Hebrew versions of both measures: along with questions on basic demographic data, were self-administered by students in the first year class (N = 46) at the medical school of the Ben-Gurion University of the Negev, Israel, during the Summer Preparatory Course. Their ages ranged from 17 to 28 yr., with an average of 21.6 yr. There were 29 men and 17 women. The correlation found between sense of coherence and A-trait (Pearson T = -.77, p = ,001) provides suong support for the hypothesis. No significant differences in scores were found by age (Pearson T = -.02 on A-trait and .12 on sense of coherence). No significant differences by sex were noted (t test). The mean score for men on A-trait was 32.96 (SD = 7.32) and for women 34.76 (SD = 8.14); on sense of coherence, rhe mean score for men was 152.52 (SD = 15.24) and for women 149.94 (SD = 17.74). In an earlier study of A-trait among 131 students in four classes of this medical school, age and sex differences were significant, with women and younger students reporting higher anxietg than men and older students (3). The strong negative relationship found between sense of coherence and A-trait scores raises a basic theoretical question: are these two measures, derived from different conceptual approaches, actually measuring the same hen omen on?