Safety Guidelines Research Articles

Risk assessment and origin of metals in chicken meat and its organs from a commercial poultry farm in Akwa Ibom state, Nigeria

Contamination of chicken with metals is on the increase, despite its known attendant health risks to human consumers. The study aimed to evaluate the concentration of some metals in various organs of chicken, their sources, and the health risks they pose to human consumers. Samples of liver, meat, gizzard, borehole water, soil, diets, and droppings were investigated for the presence of some metals (Cr, Co, Mn, Zn, Al, As, Cd, Ni, and Hg), and their sources using principal component analysis (PCA). In addition, health risk assessment was manually computed using estimated daily intake (EDI), target hazard quotient (THQ), hazard index (HI), and carcinogenic risk (CR) parameters. Cr, Mn, Co, and Zn accumulated more in the liver, while Cd and Ni were only observed in the gizzard. The starter diet recorded higher levels of all the metals compared to the grower and finisher diets except for As. All the metals were detected in the poultry surrounding soil and the drinking water of the birds except for Hg. Furthermore, PCA implicated the soil, water, and diets of the birds as the sources of these metals. The THQ, HI, and CR due to the dietary intake of the gizzard indicate a risk of cancer in children and adults. There is a need to ensure that the identified sources of these metals (soil, water, and diets) are routinely monitored to ensure compliance with safety guidelines.

The Road Ahead: A Survey of Autonomous Vehicle Challenges and Opportunities

This comprehensive study delves into the rapidly advancing field of autonomous vehicles (AVs). We explore the core technologies that enable AVs to navigate, perceive their surroundings, make informed decisions, and control their movements. The intricate interplay between sensor fusion, localization and mapping, planning algorithms, and control systems is examined. A critical focus of this research is on the ethical and societal implications of AV deployment. We analyze the crucial considerations surrounding safety, security, legal frameworks, and ethical guidelines that must be addressed to ensure responsible adoption of AVs. The potential social and economic impacts of widespread AV adoption are examined, including implications for transportation infrastructure, job markets, and urban planning .Furthermore, this study explores the exciting future directions of AV technology. We discuss emerging trends and innovations, such as the integration of artificial intelligence and machine learning, advancements in sensor technology, and the development of advanced communication networks. These developments hold the promise of further enhancing the capabilities and reliability of AVs, paving the way for a future where autonomous transportation becomes a ubiquitous part of our daily lives. Keywords and Phrases: Autonomous Vehicles, Sensor Fusion, Localization and Mapping, Planning Algorithms, Control Systems, Safety, Security, Legal Frameworks, Ethical Considerations, Social Impact, Economic Impact, Future Directions.

Impact of Operational Parameters on Pathogen Lethality in Dry and Semi-dry Uncooked Fermented Sausages

The safety of uncooked fermented, dried sausages relies upon controlled fermentation and drying that inactivates pathogenic bacteria. Current guidelines for the production of fermented sausages by the United States Department of Agriculture (USDA) Food Safety Inspection Services (FSIS) and related research highlight specific safety parameters. The confidence that processing steps, which do not include cooking, inherently mitigate microbial risks, is challenged by the resilience of pathogens in the dry and acidic environments of these food products. The aim of this work was to examine the length of drying required to achieve a target pathogen reduction across a range of sausage diameters. This study investigated the relationship between product diameter and time required to achieve target reductions of Escherichia coli O157:H7, Salmonella enterica, and Listeria monocytogenes, as well as the attainment of specific water activity (aw). The research utilized salami and summer sausage with diameters of 18 mm, 30 mm, 60 mm, 90 mm, and 110 mm. Sausage batter was inoculated with 5 strains each of E. coli O157:H7, L. monocytogenes, and S. enterica. Inoculated sausages were processed with fermentation and drying protocols for each sausage type. Smaller diameter sausages reached both the desired pathogen reduction and target aw of 0.85 sooner than larger ones. However, the time to achieve the target aw did not align with the time to achieve the pathogen reduction targets, suggesting that aw alone is not a reliable indicator of safety. Another finding was larger sausages achieved the target pathogen reduction without reaching the target aw, suggesting complex relationship between aw, diameter, and pathogen inactivation. These data support the need for food safety guidelines that consider drying duration, aw, and pathogen behavior for varying sausage diameters. This research contributes to developing more precise safety protocols for producing dry and semi-dry fermented sausages.

The IoT Integrated Electric Vehicle Fire Detection System: Case Study of IMEI TEAM UMSIDA

Abstract—In the modern era, electric vehicle technology is rapidly developing and emerging as a more environmentally friendly option than fossil fuel vehicles. Despite its many advantages, electric vehicles face safety concerns, especially fire hazards caused by problems with the battery, electrical system, or human error. Fires in electric vehicles can occur due to problems with the lithium-ion battery, accidents, or improper maintenance. Although rare, this risk needs to be considered by following maintenance and safety guidelines. Fire detection systems in electric vehicles are designed to detect and respond to potential fires, provide early warning, and take preventive or emergency action. The system uses NodeMCU esp8266 as the microcontroller, which is connected with a smartphone via WiFi. Data from the MQ2 sensor and the fire sensor are sent and recorded on the IoT platform on the smartphone. This tool is able to detect fires in real-time, but unstable internet or WiFi quality can affect data transmission. Thus, this system is expected to increase safety and reduce the risk of fire in electric vehicles, so that people feel safer and more confident in using this environmentally friendly technology. Keywords— Electric Vehicles; Fie Detector; Monitoring

Natural radionuclide profiles and radiological risks in soils and rocks of the Koytash-Ugam Range, Uzbekistan.

This investigation quantifies the activity concentrations of natural radionuclides (226Ra, 232Th, and 40K) in the soils and certain rocks of the Koytash-Ugam Range, Uzbekistan, and assesses their radiological risks. Gamma-spectrometric analysis of soil and rock samples revealed activity concentrations ranging from 456.2 ± 56.0 to 813.9 ± 76.0Bqkg-1 for 40K, 18.2 ± 6.3 to 70.0 ± 12.0Bqkg-1 for 226Ra, and 30.1 ± 2.9 to 57.9 ± 10Bqkg-1 for 232Th. This data indicates a heterogeneous distribution of radionuclides, informing radiation safety and health risk assessments on a global scale. The calculation of radiological hazard indices, including the alpha-index (ranging from 0.09 to 0.35), gamma-index (ranging from 0.40 to 0.73), and both internal (ranging from 0.40 to 0.54) and external (ranging from 0.36 to 0.54) hazard indices, was undertaken to ascertain potential health risks. The radium equivalent activity ranged from 108.4 to 199.3Bqkg-1, and the absorbed dose rates were 51.0-93.3 nGy h-1 indoors and 96.6-178.2 nGy h-1 outdoors. These metrics underlie the estimated annual effective dose of 536.5-988.5 × 10-3mSv y-1, highlighting the variability in radiation exposure. Additionally, the potential lifetime cancer risk was projected at 1770.4 to 3262.0 per million, with an annual gonadal dose equivalent of 361.9 to 655.5 μSv y-1, reflecting natural background radiation influence. The results underscore the importance of safe material use in construction and the necessity for routine natural radioactivity monitoring. Radon flux density (RFD) values within acceptable construction limits (26-176mBqm-2s-1) suggest the area's suitability for development, considering recommended safety guidelines. This study not only aids local environmental and public health frameworks but also enriches the international knowledge base, facilitating comparative studies for the advancement of global radiation protection standards. Through a detailed examination of radionuclide distribution in an under-researched area, our research highlights the critical need for integrated international approaches to natural radiological hazard assessment.

Patient safety initiatives and practices in Nigerian healthcare settings: A comprehensive analysis of current knowledge, challenges, and barriers

The imperative of patient safety in healthcare takes a central stage, more so in the context of Nigeria. This review aims to provide a comprehensive understanding of the patient safety landscape in Nigeria, drawing on 12 empirical studies. This study aims to elucidate the multifarious challenges and barriers health-care professionals encounter in Nigeria concerning patient safety. Concurrently, it delves into the prevailing patient safety culture and the factors shaping it. This study used secondary data to conduct a systematic review of existing literature; 12 studies, spanning from 2015 to 2022, were meticulously examined. These explorations cover a broad spectrum of patient safety aspects in Nigeria, focusing particularly on the insights of nurses and doctors. Through the use of thematic analysis, the studies’ synthesis illuminates a significant gap between the envisioned safety protocols and their on-ground realization. Exacerbating this challenge is the acute lack of resources, which invariably hampers the quality of care. In addition, barriers to effective communication and inadequate reporting mechanisms emerge as significant obstacles. The deficiencies in consistent training and education are also prominent, which stand as potential vulnerabilities in the system. The palpable need for heightened awareness, emphasis on recurrent training initiatives, and strict adherence to established safety guidelines are amplifying these concerns. It was, thus, concluded that the healthcare trajectory in Nigeria, as informed by this review, underscores a pressing need for systemic interventions to elevate patient safety standards. Such a transformative journey demands the concerted efforts of all stakeholders, fostering an environment that prioritizes patient safety and enhances the overall trust in Nigeria’s healthcare system.

Effects of Continuous Prenatal Low Dose Rate Irradiation on Neurobehavior, Hippocampal Cellularity, Messenger RNA and MicroRNA Expression on B6C3F1 Mice.

Epidemiological, experimental, and ecological data have indicated the controversial effect of in utero chronic low dose rate (<6 mGy/h) with accumulative low (≤100 mGy) or high (>100 mGy) dose radiation exposure. Our main goal of this study was to examine if different low dose rates of chronic pre- and/or post-natal radiation exposure with accumulative high doses could induce hippocampal cellular, mRNA, and miRNA changes leading to neuropsychiatric disorders. The comprehensive mouse phenotypic traits, organ weight, pathological, and blood mRNA and miRNA changes were also studied. Using different approaches including SmithKline, Harwell, Imperial College, Royal Hospital, Phenotype Assessment (SHIRPA), neurobehavioral tests, pathological examination, immunohistochemistry, mRNA and miRNA sequencing, and real-time quantitative polymerase chain reaction (qRT-PCR) validation, we found that in prenatally irradiated (100 mGy/d for 18 days with an accumulative dose of 1.8 Gy) 1-year-old mice, no cellular changes, including immature neurons in the subgranular zone, mature neurons and glial cells in the hilus of the dentate gyrus and development of cognitive impairment, neuropsychiatric disorders, occurred. However, a significant reduction in body weight and mass index (BMI) was indicated by the SHIRPA test. A reduced exploratory behavior was shown by an open field test. Organ weights showed significant reductions in the testes, kidneys, heart, liver and epididymides with no abnormal pathology. mRNA and miRNA sequencing and qRT-PCR validation revealed the upregulation of Rubcnl and Abhd14b, and downregulation of Hspa1b, P4ha1, and Banp genes in both the hippocampus and blood of mice prenatally irradiated with 100 mGy/d. Meanwhile, downregulation of miR-448-3p and miR1298-5p in the hippocampus, miR-320-3p, miR-423-5p, miR-486b-5p, miR-486b-3p, miR-423-3p, miR-652-3p, miR-324-3p, miR-181b-5p, miR-let-7b, and miR-6904-5p in the blood was induced. The target scan revealed that Rubcnl is one of the miR-181b-5p targets in the blood. We, therefore, concluded that prenatal chronic irradiation with a low dose rate of 100 mGy/d and accumulative dose of 1.8 Gy or below might not induce significant adverse health effects on the offspring. Further study of different low dose rate radiation exposures with accumulative high doses may provide threshold doses for authorities or regulators to set new radiation safety guidelines to replace those extrapolated from acute high dose/dose rate irradiation to reduce unnecessary emergency evacuation or spending once a nuclear accident or leakage occurs.

Rapid lake ice structure changes across Swedish lakes puts public ice safety at risk

Lakes are rapidly losing ice under global warming, but little is known about ice structure changes. Ice structure is a key regulator of ice stability and thus safety, affecting activities on ice. Here, we analysed spatial and temporal variations in ice structure across 21 Swedish lakes, spanning from 55 to 69 °N, and over five decades. We found regional differences in ice structure, with fastest changes occurring in southern Sweden. The stable clear ice layer was particularly sensitive to warming, showing a rapid decline. The number of days when temperatures exceeded the freezing point during the ice cover period was identified as a strong driver for how ice was structured. Since there is a high risk for increased occurrences of unsafe ice conditions under predicted air temperature changes, we recommend re-establishing ice structure monitoring programmes, informing society on the increased risks of being on ice and including ice structure to safety guidelines.

The role of nurses' adherence to clinical safety guidelines in linking nurse practice environment to missed nursing care.

While the nurse practice environment's vital role in shaping patient care outcomes is well established, the precise mechanisms through which it influences missed nursing care remain unexplored. Hence, this study examined the mediating role of adherence to clinical safety guidelines in the relationship between the nurse practice environment and missed nursing care. This descriptive, cross-sectional study involved 1237 nurses from 11 governorates in the Sultanate of Oman. Data were collected using three standardized scales: the Patient Safety Adherence Scale, the Practice Environment Scale of the Nursing Work Index, and the Missed Nursing Care Scale. A favorable nurse practice environment was associated with higher adherence to clinical safety guidelines (β = 2.492, p < 0.001) and a lower frequency of missed nursing care (β = -0.2919, p = 0.015). Adherence to clinical safety guidelines partially mediated the relationship between the nurse practice environment and missed nursing care (β = -0.055, p < 0.001). Enhancing the nurse practice environment plays a crucial role in improving nurses' adherence to clinical safety guidelines, which in turn reduces compromised nursing care. Healthcare administrators and policymakers should prioritize improving working conditions to enhance nurses' adherence to clinical safety guidelines, thereby minimizing the occurrence of missed care and improving overall patient outcomes.

Interventional human ocular safety experiments for 222-nm far-ultraviolet-C lamp irradiation.

The study aimed to directly assess the ocular safety of 222-nm far-ultraviolet-C (UVC) irradiation in humans, given the limited clinical trials in this area. This wavelength offers the potential for safe and effective microbial inactivation in occupied spaces, but its safety profile for human eyes requires thorough investigation. This prospective, interventional study involved five subjects aged 29-47 years, who were exposed to 222-nm UVC at doses of 22, 50, and 75 mJ/cm2. The subjects were monitored using custom-made glasses with a UV-cut filter on one eye to serve as a control. UVC irradiation was conducted using a KrCl excimer lamp, and ocular examinations were performed prior to exposure, 24 h post-exposure, and at 1, 3, and 6 months. Parameters assessed included visual acuity, refractive error, corneal endothelial density, corneal erosion scores, and conjunctival hyperemia scores. The study found no clinically significant photokeratitis or long-term eye damage across the five subjects, even at the highest dose of 75 mJ/cm2. Temporary ocular discomfort, including sensations of dryness and epiphora, was reported, but these symptoms subsided within hours after irradiation. The findings indicate that 222-nm far-UVC irradiation up to 75 mJ/cm2 does not cause "clinically significant photokeratitis" or long-term ocular damage, though it may induce temporary discomfort. This supports the safe use of 222-nm UVC for germicidal applications in occupied environments, providing a basis for revised safety guidelines.

Assessing thermal hazards and toxicity of raw biomass particles from prevalent agricultural crops in China

Fire and explosion hazards pose significant safety concerns in the processing and storage of biomass particles, warranting the safe utilization of these particles. This study employed scanning electron microscopy, thermogravimetric analysis, and cone calorimetry to investigate the thermal hazards and toxicity of raw biomass particles from four prevalent agricultural crops in China: rice, sorghum, corn, and reed. Among the samples, corn exhibited the highest heat output of 8006.82 J/g throughout the thermal decomposition process. The quantitative evaluation of critical heat flux, heat release rate intensity, fire growth rate index (FIGRA), post-ignition fire acceleration (PIFA) and flashover potential (X) revealed a substantial fire risk inherent to all the examined straw samples. Notably, corn displayed the lowest FIGRA value of 8.30 kW/m2 s, while rice demonstrated the minimum PIFA value of 16.11 kW/m2 s. Moreover, the X values for all four biomass particle types exceeded 10 under varying external heat flux levels, indicating their high propensity for fire hazards. Analysis of CO and CO2 emissions during combustion showed all four biomass samples exhibited high concentrations throughout, from the initial stages to the end. The present study offers crucial insights for formulating comprehensive fire safety guidelines tailored to the storage and processing of biomass particles.

The Use of Fire Dynamics System (NIST) in Determining The Architecture of Educational Spaces for Children and Young People

Objective: This study aims to investigate the potential of the Fire Dynamics Simulator (FDS) software, developed by the National Institute of Standards and Technology (NIST), as a tool to assess and improve Fire Safety (FS) in educational environments, specifically in the classrooms of CEFET in Araxá (MG), Brazil. Theoretical Framework: The research is based on the importance of fire safety in educational environments, highlighting the vulnerability of children and young people. Concepts of fire behavior, smoke propagation, and thermal conditions in buildings are addressed. Method: The methodology adopted for this research involves detailed computer simulations using FDS to analyze different fire scenarios. The simulation results were validated with the PyroSim software. Data collection was conducted through these simulations, generating robust empirical data that support the review and development of specific regulations. Results and Discussion: The results indicate that FDS is an important ally in promoting fire safety in educational buildings. The simulations showed the effectiveness of FDS in predicting fire behavior, smoke propagation, and thermal conditions, helping to prevent and minimize potential damages. The discussion contextualizes these results, highlighting the need for accurate empirical data to strengthen Brazilian fire safety legislation. Research Implications: The practical and theoretical implications of this research are discussed, providing insights into how the results can be applied to positively influence legislation, optimize architectural designs, and promote safety guidelines in educational institutions in Brazil. Originality/Value: This study significantly contributes to the advancement of knowledge and practices in FS. The originality of the research lies in the application of FDS for simulations in educational environments, offering a robust tool for evaluating and improving fire safety.

A short-term exposure to saxitoxin triggers a multitude of deleterious effects in Daphnia magna at levels deemed safe for human health

Harmful algal blooms and the toxins produced during these events are a human and environmental health concern worldwide. Saxitoxin and its derivatives are potent natural aquatic neurotoxins produced by certain freshwater cyanobacteria and marine algae species during these bloom events. Saxitoxins effects on human health are well studied, however its effects on aquatic biota are still largely unexplored. This work aims at evaluating the effects of a pulse acute exposure (24 h) of the model cladoceran Daphnia magna to 30 μg saxitoxin L−1, which corresponds to the safety guideline established by the World Health Organization (WHO) for these toxins in recreational freshwaters. Saxitoxin effects were assessed through a comprehensive array of biochemical (antioxidant enzymes activity and lipid peroxidation), genotoxicity (alkaline comet assay), neurotoxicity (total cholinesterases activity), behavioral (swimming patterns), physiological (feeding rate and heart rate), and epigenetic (total 5-mC DNA methylation) biomarkers. Exposure resulted in decreased feeding rate, heart rate, total cholinesterases activity and catalase activity. Contrarily, other antioxidant enzymes, namely glutathione-S-transferases and selenium-dependent Glutathione peroxidase had their activity increased, together with lipid peroxidation levels. The enhancement of the antioxidant enzymes was not sufficient to prevent oxidative damage, as underpinned by lipid peroxidation enhancement. Accordingly, average DNA damage level was significantly increased in STX-exposed daphnids. Total DNA 5-mC level was significantly decreased in exposed organisms. Results showed that even a short-term exposure to saxitoxin causes significant effects on critical molecular and cellular pathways and modulates swimming patterns in D. magna individuals. This study highlights sub-lethal effects caused by saxitoxin in D. magna, suggesting that these toxins may represent a marked challenge to their thriving even at a concentration deemed safe for humans by the WHO.

New approach methodologies to confirm developmental toxicity of pharmaceuticals based on weight of evidence

The aim of embryo-fetal developmental toxicity assessments for pharmaceuticals is to inform potential risk of adverse pregnancy outcome, which has traditionally relied on studies in pregnant animals. Recent updates to international safety guidelines (ICH S5R3) have incorporated information on how to use weight of evidence and alternative assays to reduce animal use while still informing risk of fetal harm. Uptake of these alternative approaches has been slow due to limitations in understanding how alternative assays translate to in vivo effects and then relevance to human exposure. To understand the predictivity of new approach methodologies for developmental toxicity (DevTox NAMs), we used two pharmaceutical examples (glasdegib and lorlatinib) to illustrate the value of DevTox NAMs to complement weight of evidence (WoE) assessments while considering the relationship of concentration-effect levels in NAMs to in vivo studies. The in vitro results generated in a battery of assays (mEST, rWEC, zebrafish, and human based stem cells) confirmed the WoE based on literature and further confirmed by preliminary embryo-fetal development data. The data generated for these two compounds supports integrating DevTox NAMs into the developmental toxicity assessment for advanced cancer indications.

Delphi study for developing a checklist of adverse events associated with acupotomy

BackgroundAcupotomy, a more invasive procedure than acupuncture, involves the use of a thicker needle with an integrated knife at the tip, necessitating safety research. We aimed to define relevant adverse events (AEs) and create a standardized form of the ACUPOtomy-related AEs CHECKlist (ACUPOCHECK). MethodsBefore conducting the Delphi process, a systematic review and pilot prospective study were conducted to gather information on previously reported AEs. Using these data, pilot versions of the ACUPOCHECK and Delphi questionnaires were developed. The Delphi questionnaire involved selecting types of AE for inclusion, establishing separate criteria for acupotomy-related AEs, and achieving a consensus on AE assessment. Thirteen Korean doctors with experience in acupotomy or AE research were recruited to participate in each Delphi round. Consensus was considered to have been reached if the critical value for the content validity ratio met or exceeded 0.538. ResultsThe final ACUPOCHECK was developed using four rounds of the Delphi method and one face-to-face consensus meeting. It included 12 local AEs (pain, hemorrhage, bruise, hematoma, edema, pruritus, rash, infection, nerve damage, dysesthesia, movement impairment, and pneumothorax) and 14 systemic AEs (disease aggravation, needle fatigue, sleepiness, procedural nausea, procedural vomiting, procedural headache, procedural dizziness, sweating, procedural shock, syncope, dyspnea, procedural pain, sleep disorder, and postprocedural infection). Separate criteria were established for pain, hemorrhage and bruising: pain was defined as pain that occurrs during daily activities and persists for longer than 72 h, hemorrhage as bleeding that continues for ≥ 3 min despite pressure application, and bruising as having a bruise with a diameter of ≥ 3 cm. Open-ended descriptions were allowed for AEs not covered by the checklist, and severity and causality were assessed using the Common Terminology Criteria for Adverse Events and modified World Health Organization-Uppsala Monitoring Center criteria. ConclusionACUPOCHECK provides a standardization framework that can help research on traditional practices as well as new tools and techniques that are more invasive and may cause more severe AEs. Subsequent studies will use ACUPOCHECK to develop rational safety guidelines for acupotomy techniques.Please cite this article as: Jun H, Lee H, Yoon SH, Kwon CY, Jeon D, Lee JH, Leem J. Delphi study for developing a checklist of adverse events associated with acupotomy. J Integr Med. 2024; 22(5): 579–587.

Radiation safety guidelines For 3D CBCT Imaging: A dental review

Radiation safety guidelines For 3D CBCT Imaging: A dental review

Radiation safety guidelines For 3D CBCT Imaging: A dental review

Radiation safety guidelines For 3D CBCT Imaging: A dental review

The economic impact of COVID-19 on Syrian Refugees in Jordan: A review of existing evidence and policies

The global COVID-19 crisis has precipitated an economic downturn in many countries, subsequently raising concerns about the potential challenges faced by marginalized populations, such as refugees, in accessing essential healthcare, hygiene facilities, and critical health information and safety guidelines within the context of Jordan. Consequently, it is of paramount importance to investigate and evaluate the specific economic hurdles related to COVID-19 that refugees are encountering. This inquiry will serve as a valuable foundation for shaping public health interventions aimed at containing the virus’s spread and guiding policymakers on strategies to enhance the well-being of refugees in Jordan. This paper offers a comprehensive examination of Syrian refugees in Jordan, including an analysis of the policies implemented by Jordan concerning Syrian refugees in the context of the COVID-19 pandemic. Moreover, the report assesses whether international assistance, both through bilateral and multilateral channels, can mitigate the impact of COVID-19 on Jordan’s capacity to continue hosting Syrian refugees. It also delves into the economic consequences of COVID-19, covering aspects such as poverty, education, the health sector budget, healthcare accessibility, essential needs, livelihoods, the labor market, and food security among Syrian refugees in Jordan.

Analysis of Risk Factors Related to Nurses' Attitudes and Patient Safety Culture Implementation

Patient safety is a critical global concern, with millions of adverse events occurring annually. Nurses' attitudes towards patient safety culture are pivotal in its successful implementation. This study aimed to assess the risk factors related to nurses' attitudes towards patient safety culture and its relationship with the implementation of patient safety culture in a public hospital dr. H. Moch. Ansari Saleh in Banjarmasin, Indonesia. A cross-sectional study was conducted among nurses working in a public hospital dr. H. Moch. Ansari Saleh in Banjarmasin, Indonesia. Data were collected using a questionnaire adapted from the National Patient Safety Guidelines and the AHRQ Hospital Survey on Patient Safety. The questionnaire assessed nurses' attitudes towards patient safety, the implementation of patient safety culture, and potential risk factors such as age, gender, years of experience, and workload. Data were analyzed using descriptive statistics, Spearman's rank correlation coefficient, and multivariate logistic regression. A total of 85 nurses participated in the study. The majority of nurses (81.2%) exhibited a moderate attitude towards patient safety, while 83.5% reported a moderate level of patient safety culture implementation. Spearman's rank correlation analysis revealed a weak positive correlation (rho = 0.417, p = 0.01) between nurses' attitudes and the implementation of patient safety culture. Multivariate logistic regression analysis identified age (OR = 1.12, 95% CI = 1.01-1.24) and workload (OR = 1.18, 95% CI = 1.05-1.33) as significant risk factors associated with a less positive attitude towards patient safety culture. In conclusion, while there is a positive relationship between nurses' attitudes and patient safety culture implementation, the relationship is weak. Age and workload were identified as significant risk factors for a less positive attitude towards patient safety culture. These findings highlight the need for targeted interventions to address these risk factors and enhance nurses' attitudes, thereby strengthening patient safety culture in the hospital.

How do age compositions affect pedestrian dynamics on stairways? Findings from controlled experiments

Understanding pedestrian dynamics for different age compositions is paramount for enhancing their safety level on stairways in normal and evacuation conditions. In this study, we illustrate the findings of a series of single-file pedestrian flow experiments on stairways. This experiment was carried out with 131 participants having different age compositions, including preschool students (4–5 years), primary school students (8–10 years), middle school students (12–14 years), middle-aged pedestrians (27–57 years), and the elderly pedestrians (63–81 years). We collect data using three experimental settings: individual experiments with age homogeneity, single-file pedestrian experiments with age homogeneity, and single-file pedestrian experiments with age-mixed. Our findings show that age plays a substantive non-linear impact on individual unconstrained ascending and descending speeds. In addition, we developed a linear regression model that predicts the pedestrians’ free speed of different ages on stairways. Then, the effects of age compositions on pedestrian dynamics with fundamental diagrams (i.e., speed-density and specific flow-density relations) are analysed, and the maximum specific flow of age homogeneity is higher than that of age-mixed scenarios. Finally, we illustrate how the headway distance impacts participants’ ascending and descending speeds in both age-homogeneity and age-mixed conditions. As such, these new experimental results can provide the foundation for future calibration and validation of pedestrian evacuation models as well as insight into safety guidelines.