Abstract − The Occupational health and safety is a discipline that prevents work accidents and occupational diseases with a proactive method. For employee health, countries have legal responsibilities within the scope of international conventions, and employers have national responsibilities. It is obligatory for employers to carry out risk assessments, provide occupational safety trainings, carry out inspections, employ occupational safety specialists and workplace physicians, and record all work regard work safety. In countries, inspections are carried out with labor inspectors and private companies provide occupational safety services. However, it is difficult for the authorities to monitor occupational safety in large industrial facilities such as petrochemicals and refineries, where the flow of workers, materials and work equipment is too much and very fast. As workplace capacity, number of employees and material flow increase, the type and number of work accidents and occupational diseases also increase. Artificial intelligence technologies facilitate these follow-ups. The purpose of this article is to investigate the proactive prevention of the factors that cause work accidents and occupational diseases with supervised machine learning algorithms in different sectors. A literature search was conducted on sciencedirect, scopus, googlescholar databases. It has been examined what kind of algorithms are used in which sectors. According to the studies in the literature and applications in different sectors, the data collected with sensors and stored with cloud computing are fed to the relevant supervised machine learning algorithms that have been trained and tested before, and the factors that cause work accidents and occupational diseases are determined in advance. In addition to sound, image, health, location and environment data, physical parameters such as distance, level and pressure are monitored instantly with sensors. Managers are warned when a dangerous situation or behavior is detected in and threshold values are exceeded. In addition to employee and vehicle location tracking, predictive maintenance is provided by monitoring the performance of work and production vehicles. With the decrease in occupational accidents and diseases, occupational safety performance increases and costs decrease.