Sacrificial Template Research Articles

Ce doped Ni(OH)2/Ni-MOF nanosheets as an efficient oxygen evolution and urea oxidation reactions electrocatalyst

Metal-organic frameworks (MOFs) are widely recognized as precursors or sacrificial templates for the synthesis of target catalysts on account of their high porosity and high active surface area. Elemental doping strategy is considered as an effective method for the synthesis of efficient and stable catalysts for electrolytic water. Therefore, in this paper, Ce-doped Ni(OH)2 nanoparticles and Ni-MOF nanosheets composites were synthesized by electrodeposition using Ni-MOF as precursor. Catalyst Ce–Ni(OH)2@Ni-MOF/NF displays excellent OER performance, requiring only 193 mV and 279 mV overpotentials to realize current densities of 10 mA cm−2 and 100 mA cm−2, respectively, while the UOR performance was very remarkable, only a potential of 1.28 V was demanded to reach a current density of 10 mA cm−2. In addition, no obvious change in the overpotential was noticed during the stability test of 16 h, indicating good stability of Ce–Ni(OH)2@Ni-MOF/NF. This study provides a meaningful reference for the design of an efficient and stable environmental friendly electrocatalyst.

Manganese Dioxide Nanoplatform with a Hollow Rhombic Dodecahedron Morphology for Drug Delivery.

Manganese dioxide (MnO2) is considered as a promising drug carrier material suitable for the tumor microenvironment while lacking conducive structures for drug loading. Herein, we construct a MnO2 nanoplatform with a hollow rhombic dodecahedral morphology for drug delivery. In this work, we obtained zeolitic imidazolate framework nanoparticles (ZIF-90 NPs) via a coordination reaction. Furthermore, the drug-loading nanoparticles (ZIF-90/DOX NPs) were obtained by Schiff's base reaction and then selected as a sacrificial template to obtain the hollow nanoplatforms (ZIF-90@MnO2 NPs). Moreover, the photothermal effect and multiresponsive drug release behaviors were revealed by loading the photothermal agent IR-820 and the anticancer drug doxorubicin hydrochloride (DOX). Our study demonstrates that the ZIF-90@MnO2 NPs loaded with photosensitizers exhibited excellent photothermal conversion performance. Benefiting from the hollow structure and redox activity, remarkable drug loading and release performances of ZIF-90@MnO2 NPs were achieved. It is shown that ZIF-90@MnO2 NPs achieved a satisfactory drug-loading efficiency (up to ca. 69.7%) for DOX. More promisingly, the ZIF-90@MnO2 NPs exhibited significant glutathione (GSH)/pH-responsive drug release and degradation performances. Overall, this work highlights the potential of controlled drug release of nanocarriers and offers unique insights into the design of nanocarriers with hollow structures.

Organic polymer coating induced multiple heteroatom-doped carbon framework confined Co1-xS@NPSC core-shell hexapod for advanced sodium/potassium ion batteries

Synthesis of advanced structure and multiple heteroatom-doped carbon based heterostructure materials are the key to the preparation of high-performance energy storage electrode materials. Herein, the hexapod-shaped Co1-xS@NPSC has been triumphantly prepared using hexapod ZIF-67 as the sacrificial template to prepare Co1-xS inner core and N, P, and S tri-doped carbon (NPSC) as the shell through the carbonization of the organic polymer precursor. When applied as anode for Na+ batteries (SIBs) and K+ batteries (PIBs), Co1-xS@NPSC presents the high reversible specific capability of 747.4 mAh/g at 1.0 A/g after 235 cycles and 387.8 mAh/g at 5.0 A/g after 760 cycles for SIBs, as well as 326.7 mAh/g at 1.0 A/g after 180 cycles for PIBs. The excellent storage capacity and rate capability of Co1-xS@NPSC is ascribed to hexapod structure of ZIF-67 unlike the common dodecahedron, which is constructed with interior porous and exterior framework repository, donating supplemental active sites, and doping of multiple heteroatoms forming organic polymer coating inhibiting the volume expansion and restrains the agglomeration of Co1-xS nanoparticles. This approach has paved a bright avenue to exploit promising anode materials with novel structure and hetero-atom doping for high-performance energy storage devices.

Ternary ordered assembled piezoelectric composite for self-powered ammonia detection

The sensing performance of gas sensors is determined by three key factors of sensing, transducing and utilization ratio of sensing body. However, these three factors are structurally and functionally independent for most existing gas sensors, restricting the integration and multi-functionalization of the gas discrimination. Herein, we reported a ternary ordered assembly strategy to synchronously and sympatrically integrate and optimize the three key factors in one single device. The in-situ polymerized Ppy coating serves as the sensing component while the embedded PZT nanofiller functions as transducing element, where the utilization ratio of sensing body is directly regulated by the porosity and sensing coating thickness via controlling the sugar granule loading amount and polymerization time. By tuning in-situ polymerization quantity, sacrificial templating amount and transducing loading as well as poling time, an optimal ammonia sensing response was accomplished with a responsivity of 387% at the 100 ppm, a sensitivity of 4.29% ppm−1, excellent selectivity and long-term stability. A theoretical gas-sensitive model was established by combining the experimental characterization with finite element calculation and phase-field simulation. This work throws lights on the fundamental gas sensing mechanism and provides a promising paradigm for developing multi-level controllable sensing devices for physiological assessment and environmental monitoring.

In Situ Electrochemical Construction of CuN3@CuCl Hybrids for Controllable Energy Release and Self-Passivation Ability.

Advanced energetic materials (EMs) play a crucial role in the advancement of microenergetic systems as actuation parts, igniters, propulsion units, and power. The sustainable electrosynthesis of EMs has gained momentum and achieved substantial improvements in the past decade. This study presents the facile synthesis of a new type of high-performance CuN3@CuCl hybrids via a co-electrodeposition methodology utilizing porous Cu as the sacrificial template. The composition, morphology, and energetic characteristics of the CuN3@CuCl hybrids can be easily tuned by adjusting the deposition times. The resulting hybrids demonstrate remarkable energy output (1120 J·g-1) and good laser-induced initiating ability. As compared with porous CuN3, the uniform doping of inert CuCl enhances the electrostatic safety of the hybridized material without compromising its overall energetic characteristics. Notably, the special oxidizing behavior of CuCl gradually lowers the susceptibility of the hybrid material to laser and electrostatic stimulation. This has significant implications for the passivation or self-destruction of highly sensitive EMs. Overall, this study pioneers a new path for the development of MEMS-compatible EMs, facilitating further microenergetic applications.

Synthesis of polymetallic oxides hollow spheres with superior activity, resistance to SO2, H2O and metal poisons for low-temperature NH3‑selective catalytic reduction of NOx

NH3‑selective catalytic reduction as the fascinating technology for complete NOx removal, the key in practical applications is to explore advanced catalysts with high catalytic reactivity and stability at low temperature. Herein, a series of hollow spherical AMnOx (A = Ce, Cu, Ni) catalysts was fabricated by using carbon nanospheres as sacrificial template. Characterization analysis including XRD, ICP, BET, SEM, TEM, H2-TPR, NH3-TPD, XPS, in situ DRIFTS together with kinetic studies were applied to acquire knowledge of the morphological structure and surface features of the catalysts as-prepared. We also performed a comparative study on three samples with regard to their SCR activity at low temperatures. Notable, the catalytic activity of the NiMnOx catalyst (95.9 %) was vastly superior to that of the CeMnOx (85.4 %) and CuMnOx (30.5 %) at 100 °C. This enhanced low-temperature activity of NiMnOx are correlated against hollow structure with more active sites, wider pore distribution, higher surface Mn content and the enhancement in surface acidity and reducibility. Even with 5 vol% H2O in the reaction gas fraction, the catalytic performance of NiMnOx hollow spheres was superior to the other two catalysts. Besides, it can be used for six consecutive runs without suffering a substantial activity loss. Additionally, the impact of various crucial process variables, including space velocity, H2O, SO2, and metal poisons, on the denitrification efficiency of NH3-SCR was examined. The current researches have a positive guiding role in the development of high-efficiency low-temperature NH3-SCR denitrification catalysts to boost NOx degradation.

Hollow structured CdS@ZnIn2S4 Z-scheme heterojunction for bifunctional photocatalytic hydrogen evolution and selective benzylamine oxidation

Photocatalytic hydrogen evolution (PHE) is frequently constrained by inadequate light utilization and the rapid combination rate of the photogenerated electron-hole pairs. Additionally, conventional PHE processes are often facilitated by the addition of sacrificial reagents to consume photo-induced holes, which makes this approach economically unfavorable. Herein, we designed a spatially separated bifunctional cocatalyst decorated Z-scheme heterojunction of hollow structured CdS (HCdS) @ZnIn2S4 (ZIS), which was prepared by a sacrificial hard template method followed by photo-deposition. Consequently, PdOx@HCdS@ZIS@Pt exhibited efficient PHE (86.38 mmol·g−1·h−1) and benzylamine (BA) oxidation coupling (164.75 mmol·g−1·h−1) with high selectivity (97.34 %). The unique hollow core-shelled morphology and bifunctional cocatalyst loading in this work hold great potential for the design and synthesis of bifunctional Z-scheme photocatalysts.

Highly Flexible and Self‐Standing Covalent Organic Framework–Metal–Organic Framework (COF–MOF) Composite Crystalline Porous Material (CPM) Membrane for Molecular Separation

AbstractCrystalline porous materials (CPMs), including covalent organic frameworks (COFs) and metal–organic frameworks (MOFs), are promising materials for advanced separation technologies. However, the challenge of transforming nanoscale CPMs into large‐area functional membranes hinders their application in the membrane separation process. Herein, a self‐standing pure COF (TpPa‐1) nanofiber membrane with high crystallinity, good flexibility, excellent mechanical properties, and scalability is prepared using an electrospinning process and polymer sacrificial template strategy. Subsequently, the COF nanofiber membrane is innovatively used to replace traditional inorganic discs, metal meshes, and polymer membranes as porous supports, and the COF–MOF composite CPM membrane is prepared through the tailorable and confined growth of zeolite imidazolium salt frame‐8 (ZIF‐8) on the surface of the COF membrane and in the gaps of the COF nanofibers. The COF–MOF composite membrane exhibits excellent permeability and significantly enhances separation selectivity for organic dyes. Moreover, MOF and COF form an interpenetrating network structure, and their similar chemical properties improve the interfacial stability between the two phases, giving the COF–MOF composite membrane good long‐term separation performance. This is the first self‐standing composite CPM membrane with excellent molecular sieving performance, which provides new insights into the design of high‐performance and robust composite membranes.

Binary Atomic Sites Enable a Confined Bidirectional Tandem Electrocatalytic Sulfur Conversion for Low-Temperature All-Solid-State Na-S Batteries.

The broader implementation of current all-solid-state Na-S batteries is still plagued by high operation temperature and inefficient sulfur utilization. And the uncontrollable sulfur speciation pathway along with the sluggish polysulfide redox kinetics further compromise the theoretical potentials of Na-S chemistry. Herein, we report a confined bidirectional tandem electrocatalysis effect to tune polysulfide electrochemistry in a novel low-temperature (80 °C) all-solid-state Na-S battery that utilizes Na3 Zr2 Si2 PO12 ceramic membrane as a platform. The bifunctional hollow sulfur matrix consisting binary atomically dispersed MnN4 and CoN4 hotspots was fabricated using a sacrificial template process. Upon discharge, CoN4 sites activate sulfur species and catalyze long-chain to short-chain polysulfides reduction, while MnN4 centers substantially accelerate the low-kinetic Na2 S4 to Na2 S directly conversion, manipulating the uniform deposition of electroactive Na2 S and avoiding the formation of irreversible products (e.g., Na2 S2 ). The intrinsic synergy of two catalytic centers benefits the Na2 S decomposition and minimizes its activation barrier during battery recharging and then efficiently mitigate the cathodic passivation. As a result, the stable cycling of all-solid-state Na-S cell delivers an attractive reversible capacity of 1060 mAh g-1 with a high CE of 98.5 % and a high energy of 1008 Wh kgcathode -1 , comparable to the liquid electrolyte cells.

Binary Atomic Sites Enable a Confined Bidirectional Tandem Electrocatalytic Sulfur Conversion for Low‐Temperature All‐Solid‐State Na−S Batteries

AbstractThe broader implementation of current all‐solid‐state Na−S batteries is still plagued by high operation temperature and inefficient sulfur utilization. And the uncontrollable sulfur speciation pathway along with the sluggish polysulfide redox kinetics further compromise the theoretical potentials of Na−S chemistry. Herein, we report a confined bidirectional tandem electrocatalysis effect to tune polysulfide electrochemistry in a novel low‐temperature (80 °C) all‐solid‐state Na−S battery that utilizes Na3Zr2Si2PO12 ceramic membrane as a platform. The bifunctional hollow sulfur matrix consisting binary atomically dispersed MnN4 and CoN4 hotspots was fabricated using a sacrificial template process. Upon discharge, CoN4 sites activate sulfur species and catalyze long‐chain to short‐chain polysulfides reduction, while MnN4 centers substantially accelerate the low‐kinetic Na2S4 to Na2S directly conversion, manipulating the uniform deposition of electroactive Na2S and avoiding the formation of irreversible products (e.g., Na2S2). The intrinsic synergy of two catalytic centers benefits the Na2S decomposition and minimizes its activation barrier during battery recharging and then efficiently mitigate the cathodic passivation. As a result, the stable cycling of all‐solid‐state Na−S cell delivers an attractive reversible capacity of 1060 mAh g−1 with a high CE of 98.5 % and a high energy of 1008 Wh kgcathode−1, comparable to the liquid electrolyte cells.

MULTILAYER DUAL-POROSITY 3D-PRINTED SCAFFOLDS TO RECREATE THE ANISOTROPIC MICROENVIRONMENT OF THE CARTILAGE

Articular cartilage is a multi-zonal tissue that coats the epiphysis of long bones and avoids its wear during motion. An unusual friction could micro-fracture this connective membrane and progress into an osteochondral defect (OD), where the affected cartilage suffers inflammation, fibrillation, and forfeiture of its anisotropic structure.Clinical treatment for ODs has been focused on micro-fracture techniques, where the defect area is removed and small incisions are performed in the subchondral bone, which allows the exudation of mesenchymal stem cells (hMSCs) to the abraded zone. However, hMSCs represent less than 0.01% of the total cell population and are not able to self-organise coherently, so the treatments fail in the long term. To select, support and steer hMSCs from the bone marrow into a specific differentiation stage, and recreate the cartilage anisotropic microenvironment, multilayer dual-porosity 3D-printed scaffolds were developed.Dual-porosity scaffolds were printed using prepared inks, containing specific ratios of poly-(d,l)lactide-co-caprolactone copolymer and gelatine microspheres of different diameters, which acted as sacrificial micro-pore templates and were leached after printing. The cell adhesion capability was investigated showing an increased cell number in dual-porosity scaffolds as compared to non-porous ones. To mimic the stiffness of the three cartilage zones, several patterns were designed, printed, and checked by dynamic-mechanical analysis under compression at 37 ºC. Three patterns with specific formulations were chosen as candidates to recreate the mechanical properties of the cartilage layers. Differentiation studies in the selected scaffolds showed the formation of mature cartilage by gene expression, protein deposition and biomolecular analysis. Given the obtained results, designed scaffolds were able to guide hMSC behaviour.In conclusion, biocompatible, multilayer and dual-porosity scaffolds with cell entrapment capability were manufactured. These anisotropic scaffolds were able to recreate the physical microenvironment of the natural cartilage, which in turn stimulated cell differentiation and the formation of mature cartilage.Acknowledgments: This work was supported by the EMAKIKER grant.

Charged hollow microgel capsules.

Responsive hollow microgels are a fascinating class of soft model systems at the crossover between polymer capsules and microgels. The presence of the cavity makes them promising materials for encapsulation and controlled release applications but also confers them an additional softness that is reflected by their peculiar behaviour in bulk and at interfaces. Their responsivity to external stimuli, such as temperature, pH, and ionic strength, can be designed from their synthesis conditions and the choice of functional moieties. So far most studies have focused on "small" hollow microgels that were mostly studied with scattering or atomic force microscopy techniques. In our previous study, we have shown that large fluorescent hollow poly(N-isopropylacrylamide) (PNIPAM) microgels could be synthesized using micrometer-sized silica particles as sacrificial templates allowing their investigation in situ via confocal microscopy. In this work, we extend this approach to charged large hollow microgels based on poly(N-isopropylacrylamide-co-itaconic acid) (P(NIPAM-co-IA)). Hereby, we compare the structure and responsivity of "neutral" (PNIPAM) and "charged" (P(NIPAM-co-IA)) hollow microgel systems synthesized under similar conditions with the same sacrificial template using confocal and atomic force microscopy and light scattering techniques. In particular, we could demonstrate the extremely soft character of the swollen charged hollow microgels and their responsivity to pH, ionic strength, and temperature. To conclude this study, the buckling behavior of the different capsules was investigated illustrating the potential of such systems to change its conformation by varying the osmotic pressure and pH conditions.

Efficient improvement in the electrochemical performance of petal-like lamellar NiMn-LDHs with affluent oxygen vacancies derived from Mn MOF-74.

Supercapacitors (SCs) as a kind of novel energy storage devices have emerged to meet the urgent requirement of environmentally friendly clean energy storage equipment. However, unsatisfactory energy density and low operating voltage tremendously restrict their practical application. Herein, petal-like lamellar NiMn-layered double hydroxide (NiMn-LDH) was successfully fabricated through a simple Ni(NO3)2 etching method with Mn MOF-74 as a sacrificial template. This NiMn-LDH 3/NF electrode exhibited an improved specific capacitance of 1410.2 F g-1 at a current density of 1 A g-1 (Mn MOF-74/NF: 172.2) owing to its high redox activity, compositional flexibility and intercalating capability. Importantly, NiMn-LDH was further optimized via a facile hydroperoxide treatment to harvest NiMn-LDH (O-LDH) with abundant oxygen vacancies, exhibiting remarkable improvement in specific capacitance (990%) compared to original MOF-74 before modification. The preparation of O-LDH enriches the electrode material engineering strategy and achieves improved electrochemical performance for application in new-generation SCs.

A bimetallic MOF-derived MnCo spinel oxide catalyst to enhance toluene catalytic degradation.

MnCo spinel oxide catalysts were successfully synthesized by the calcination of bimetallic Mn/Co-MOFs as sacrificial templates. The derived catalysts exhibited optimal catalytic activity, reusability and thermal stability for toluene oxidation, which was ascribed to their large specific surface area, higher number of octahedral metal ions and the weakest metal-oxygen bonds.

3D printed porous silicone polymer composites using table salt as a sacrificial template

The incorporation of different functional fillers into the DIW composite resin can expand the functionality of 3D printed porous materials for different applications.

Self-templated fabrication of P-doped CoMoO4-Co3O4 hollow nanocages for the efficient oxygen evolution reaction.

Finding reservoir-rich and efficient electrocatalysts for the alkaline oxygen evolution reaction (OER) is crucial for further sustainable energy development. Despite the advantages of high earth abundance, easy availability, and tunable composition, transition-metal oxides are typically considered poor electrocatalysts for the OER. In this study, a composite P-doped CoMoO4-Co3O4 hollow nanocage is deliberately synthesized through a cation-exchange, pyrolysis, and phosphorization approach using an innovative self-template strategy with ZIF-67 as the sacrificial template. Hollow nanocages provide large surface areas and abundant active sites, enhancing electron transfer. Hybridization with other components increases the number of electrochemically reactive sites and optimizes the advantages of different element components. As a result, the P-CoMoO4-Co3O4 hollow nanocage catalyst demonstrates high OER performance, with an overpotential of 279 mV at a current density of 10 mA cm-2. Additionally, P-CoMoO4-Co3O4 catalysts exhibit good dispersibility and excellent long-term stability. Experimental findings and density functional theory (DFT) calculations indicate that the phosphorus-doping effect in various aspects contributes significantly to the superior catalytic activity of P-CoMoO4-Co3O4. This work provides a valuable method for designing cost-effective P doped Co-based bimetal oxide catalysts with outstanding OER performance for industrial applications.

Encapsulation of an enzyme-immobilized smart polymer membrane in a metal-organic framework for enhancement of catalytic performance.

Encapsulation of enzymes within porous materials has shown great promise for protecting enzymes from denaturation, increasing their tolerance to harsh environments and promoting their industrialization. However, controlling the conformational freedom of the encapsulated enzymes to enhance their catalytic performance remains a great challenge. To address this issue, herein, following immobilization of GOx and HRP on a thermo-responsive porous poly(styrene-maleic-anhydride-N-isopropylacrylamide) (PSMN) membrane, a GOx-HRP@PSMN@HZIF-8 composite was fabricated by encapsulating GOx-HRP@PSMN in hollow ZIF-8 (HZIF-8) with liposome (L) as the sacrificial template. The improved conformational freedom for enzymes arising from the hollow cavity formed in ZIF-8 through the removal of L enhanced the mass transfer and dramatically promoted the catalytic activity of the composite. Interestingly, at high temperature, the coiled PN moiety in PSMN provided the confinement effect for GOx-HRP, which also significantly boosted the catalytic performance of the composites. Compared to the maximum catalytic reaction rates (Vmax) of GOx-HRP@PSMN@LZIF-8, the free enzyme and GOx-HRP@ZIF-8, the Vmax of the GOx-HRP@PSMN@HZIF-8 composite exhibited an impressive 17.8-fold, 10.8-fold and 6.0-fold enhancement at 37 °C, respectively. The proposed composites successfully demonstrated their potential as catalytic platforms for the colorimetric detection of glucose in a cascade reaction. This study paves a new way for overcoming the current limitations of immobilizing enzymes in porous materials and the use of smart polymers for the potential fabrication of enzyme@polymer@MOF composites with tunable conformational freedom and confinement effect.

Tailoring MIL-100(Fe)-derived catalyst for controlled carbon dioxide conversion and product selectivity.

Here in, we are reporting the effect of the catalyst particle size on the catalytic activity and product selectivity by understanding the strength of the interaction between the active catalyst and the reactants (CO2 and H2). In this regard, two catalytic systems having different active catalyst particle sizes and support surface areas were synthesized using metal-organic frameworks (MOF) (MIL-100(Fe)) having two crystal size ranges as sacrificial templates. The active catalyst having smaller nanoparticles exhibited greater chemisorption of hydrogen (Fe-H bond), resulting in heightened selectivity for paraffin due to hydrogenation of re-adsorbed olefins. Conversely, larger nanoparticles showed enhanced chemisorption of CO2 (Fe-C bond), leading to increased selectivity for olefins (O/P = 0.15). Additionally, a reduction in particle size boosts activity from 24% to 38.7% at 340 °C/20 bar. While, higher particle size enhances the selectivity towards C5+ from 11.1 to 45.6% at (300 °C/10 bar) and 9.6 to 21.3% at (340 °C/20 bar).

Galvanic replacement-induced preparation of bloom-like Pt23Ni77 for methanol coupled efficient hydrogen production.

Galvanic replacement reaction (GRR) leverages the difference in metal reduction potentials to regulate the structure of nanomaterials. The crucial aspect of constructing highly active catalysts lies in the precise manipulation of both the oxidative dissolution of sacrificial template metals and reductive deposition of alternate metals. Herein, we investigated the morphological transformation of metal Ni as a sacrificial template in the presence of different amounts of H2PtCl6 solution and the Pt4+ substitution of Ni to achieve the redistribution of elements on the catalyst surface, which provides superior performance in both the methanol oxidation reaction (MOR) and hydrogen evolution reaction (HER). The uniform distribution of Pt on a three-dimensional transition metal Ni substrate allows for the complete exposure of the noble metal to the catalyst surface. This distribution increases the reaction area, facilitating easy access for reactants and promoting electron transfer. Meanwhile, Pt (1.39 Å) has a larger atomic radius compared to Ni (1.24 Å), and the substitution reaction in the transition metal phase induces strong compressive strain, which effectively regulates the electronic structure of Ni.

Prevention of White Spot Lesion during Orthodontic Treatment: A Novel Bioactive Glass Nanobioadhesive

Objectives: The objective of this study is to evaluate the ability of the bioactive glass (BAG)-Bonds to inhibit the demineralization surrounding the orthodontic brackets when being exposed to an in vitro caries challenge and also simultaneously evaluate the physical and mechanical properties in order to be accepted as an orthodontic bonding agent. Materials and Methods: Preparation of mesoporous bioactive glass (MBG) used an improved sol-gel method, combining with sacrificial liquid template to MBGs with controllable particle size. Tetraethyl orthosilicate, triethyl phosphate, calcium nitrate tetrahydrate, ethanol absolute, ethyl acetate, hexadecyltrimethylammonium bromide, deionized water, and ammonium hydroxide were used. The microstructure was analyzed using a field emission gun-based scanning electron microscope (SEM). The debonding and adhesion characteristics were analyzed using an Instron Universal Testing Machine. Results: SEM analysis shows that the prepared MBG particles possess spherical morphology with generally uniform size. Novel orthodontic bonding material (BG) provides adequate mechanical and physical properties in order to be accepted as an orthodontic bonding agent since its bond strength both at the time of bonding and after 6 months in simulated salivary conditions is significantly higher than conventional bonding resin (TBXT). The bond strength was also evaluated both initially at the time of bonding as well as 6 months after being kept in simulated salivary conditions. Conclusion: These novel adhesives result in reduced demineralization surrounding orthodontic brackets and possess optimal physical and mechanical properties to be accepted as an orthodontic adhesive.