Through the clinical study of brain tumors, we had a conclusion on the cerebral mechanism which influence the sacral center on the micturition. That will be described as follows:1. The frontal lobe has something to do with inhibitory function of the micturition especially the left frontal lobe seems to be very significant.2. It is very doubtful that there is an inhibitory factor in motor area.3. The paracental lobule seems to have an inhibitory function, incontinence, however, may not appear unless both lobules are invaded.4. The possibility of the existence of an inhibitory center in the cingulate gyrus is extremely doubtful. It is out of our consideration that there exists, at least, an inhibitory center on the anterior cingulate gyrus.5. It is also doubtful that there is an inhibitory or an accelerating center in the diencephalon.6. The upper part of the mesencephalon appears to be no important center of micturition.7. It is clear that there are some accelerating center of micturition in the area of lower mesencephalon and upper medulla with the pons as its significant site (Fig. 3).