Several years ago, at a bush hospital in rural west Africa, a small boy was brought by his worried parents to see the visiting American physician. The child had begun coughing and wheezing during the previous week. Now, his every breath required great effort and resulted in a loud, wheezing, grating sound. Asthma and pneumonia were diagnosed without any trouble, and every available medication (aminophylline, steroids, antibiotics, epinephrine, β-blockers, intravenous fluid) was utilized. For five days, the 6-year-old child lay gasping with pleading eyes and whispered prayers. Nothing seemed to help, and oxygen and respirators were unknown in that part of the world. In a hospital where one nurse is responsible for 80 patients, IVs easily run dry at 2 AM. Even with a full hospital, the doctors come to the bedside two or three times each night to rewrite orders and to be sure that therapy is continuous. On
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