<h3>Background</h3> West Virginia (WV) has high rates of HPV-related cancers and lagging rates of HPV vaccination. Recent legislation in WV allows pharmacists to administer the HPV vaccine to adolescents if prescribed by a provider. The purpose of this study was to assess parent and provider views about using pharmacies to provide the HPV vaccine to adolescents. <h3>Methods</h3> Pediatric, Family Practice and OBGYN physicians within a single institution that serves rural counties were surveyed regarding HPV vaccination practice, and awareness of using pharmacies for provision. Teaching sessions with providers then reviewed the legislation and the logistics of prescribing the vaccine through a pharmacy. Six months later the same departments were surveyed regarding HPV vaccination practice, pharmacy provision, and perspectives about this pharmacy service. Parents of adolescents age 11-18 were also surveyed. Adolescent vaccination status, gender, and WV county of residence were collected, along with Likert scale questions about usefulness of pharmacy access for vaccination. Provider responses were compared before and after the teaching intervention after six months. Parental responses were compared by adolescent gender and rural/urban county designation. Proportions were compared using Chi square statistics. Institutional review board approval was obtained. <h3>Results</h3> Seventy one physicians completed the initial survey, and 45 completed the six month assessment. Only 22.5% were aware of the pharmacy legislation initially, and 64.4% were aware at six months (p= <.001). Most providers felt that pharmacy access would be beneficial for rural patients initially and at 6 months (69% vs 78%, p=0.31). Providers also felt they would be "Likely" or "Very Likely" to prescribe the vaccine to adolescents through a pharmacy, and this did not change significantly at 6 months (71.8% vs 73.3%, p=0.86). However, at 6 months only 2 providers (both OBGYN) actually reported prescribing the vaccine this way. 121 parents completed the survey, which represented 196 adolescents age 11-18. HPV vaccine completion was not affected by rural/urban county designation, but overall males were less likely to have completed the vaccine (Figure 1). Rural parents lived closer to pharmacies than their primary care providers (Figure 2), but only 16 (13.2%) parents were aware of pharmacy access for the HPV vaccine. Of parents whose adolescents had started or completed the vaccine series, 78.1% felt pharmacy access would have been "Very beneficial", and this did not vary by rural/urban designation. <h3>Conclusions</h3> Pharmacy provision of HPV vaccination is under- utilized. Both parents and physicians had favorable views on using pharmacies for adolescent HPV vaccination series completion.