Rupture Of Anterior Lens Capsule Research Articles

CASE REPORTS: Bilateral anterior lens capsule ruptures in Alport syndrome: case series and literature review

We present 3 cases of bilateral anterior lens capsule rupture, all leading to a subsequent diagnosis of Alport syndrome. Clinicians should be alert to the ocular and systemic features of Alport syndrome, especially when presented with a spontaneous rupture of the anterior lens capsule in young males. Ophthalmologists are often the first contact for patients with Alport syndrome, and a sound knowledge of the associated features will enable timely referral to other members of a multidisciplinary team required to treat such patients. Diagnosis and subsequent testing of affected families further aids in genetic counseling and early, comprehensive treatment.

Open Globe Injury with Corneal Laceration Full-Thickness, Anterior Lens Capsule Rupture, and Traumatic Cataract

Introduction: Ocular trauma is a common, preventable cause of visual impairment. Mechanical eye injuries affect the eye in many ways ranging from mild to severe morbidity. In this case, we inform the sequence of what we found in this ocular trauma and how we treat this case. Case Presentation: A 26-year-old male patient presented with pain and stiffness in the right eye. The patient was involved in an accident 16 hours before being admitted to the emergency room. Previously, the patient had been taken to a secondary hospital. No medications were given. The patient was referred directly to a tertiary hospital for further management. The visual acuity of the right eye and left eye were 1/300 and 6/6. Soft palpation indicated decreased intraocular pressure (IOP) on the right eye. Slit lamp examination found conjunctival hyperemia, full-thickness corneal laceration, irregular iris, posterior synechiae, declining pupil reflex, and hazy lens. Fundus reflex declined. The right eyeball exploration showed a membrane at the camera oculi anterior and a suspected hazy lens with mass and capsule of the lens. Doubtful prognosis on the right eyeball. Conclusions: The outcome of ocular trauma might be debatable and vary in any condition. Proper management can avoid unprecedented complications and improve patient visual results. A good perspective will also make satisfied both the patient and the physician.

Novel clinical presentation and PAX6 mutation in families with congenital aniridia.

To explore the clinical phenotype and genetic defects of families with congenital aniridia. Four Chinese families with aniridia were enrolled in this study. The detailed ocular presentations of the patients were recorded. Whole exome sequencing (BGI MGIEasy V4 chip) was used to detect the gene mutation. Sanger sequencing was performed to validate the potential pathogenic variants, and segregation analysis was performed on all available family members. By whole exome sequencing and Sanger sequencing, three recurrent mutations (c.112del, p.Arg38Glyfs*16; c.299G > A, p.Trp100* and c.718C > T, p.Arg240*) and one novel mutation (c.278_281del, p.Glu93Alafs*30) of PAX6 were identified. All the mutations were co-segregated with the phenotype in the families. We also observed spontaneous anterior lens capsule rupture in aniridia for the first time. We report spontaneous anterior lens capsule rupture as a novel phenotype of aniridia and three recurrent mutations and one novel mutation of PAX6 in families with aniridia. Our results expanded the phenotype and genotype spectra of aniridia and can help us better understand the disease.

Bilateral symmetrical spontaneous anterior capsule rupture of the cataractous lens in a child

<br>We report the management of a rare case of bilateral, symmetrical, and spontaneous anterior lens capsule rupture with total soft cataractous lens in a 7-year-old child. The patient had no other predisposing factors or systemic associations. Bilateral lens aspiration was done through the fibrosed capsular opening, which behaved like a stable capsulorhexis and hydrophobic intraocular lens was implanted. At 6 weeks follow-up, the patient had good visual outcome without any astigmatism. Although capsule rupture is reported in trauma, Alports syndrome or in hypermature cataracts, to our best knowledge this is the first case report of bilateral symmetrical spontaneous anterior capsule rupture in an otherwise normal child.<br>

Lenticular fungal infection caused by Aspergillus in a patient with traumatic corneal laceration: a case report

BackgroundTo report a case of lenticular infection caused by Aspergillus, which was diagnosed 13 weeks after traumatic corneal laceration.Case presentationA 60-year-old woman presented with traumatic corneal laceration including anterior lens capsule rupture and traumatic cataract after being hit with a chestnut in the right eye. There were multiple injuries due to tiny thorns of the chestnut, including the conjunctiva, sclera, cornea, and anterior lens capsule. But no visible foreign body was detected by slit-lamp examination. Topical corticosteroid was prescribed to resolve the conjunctival inflammation induced by the thorns of chestnut, which could have caused persistent irritation. As conjunctival injection and edema being decreased during outpatient clinical follow-up, embedded conjunctival foreign body was detected and surgically removed (1st surgery). Approximately 10 weeks after the trauma, severe inflammation of the anterior segment accompanied with hypopyon developed suddenly and at the same time embedded scleral foreign body was revealed. After removal of scleral foreign body (2nd surgery), unspecified mold species was cultured from the scleral foreign body in SDA (Sabouraud dextrose agar) plate. Suspicious corneal foreign body was removed as 3rd surgery and phacoemulsification of traumatic cataract was planned as 4th surgery. Aspergillus was finally detected from removed anterior capsule and fibrotic membrane during the operation. Fungal infection resolved successfully after administration of topical (1% voriconazole and 5% natamycin) and systemic (fluconazole) antifungal agents and phacoemulsification of traumatic cataract.ConclusionChestnut thorns can damage multiple ocular tissues simultaneously. Lens capsular rupture could result in fungal inoculation and lead to delayed lenticular fungal infection with complicated cataract formation. In cases of ocular trauma due to organic substances such as thorns and branches, the possibility of fungal infection should be considered.

Uveítis facolítica asociada a ruptura espontánea de la cápsula anterior en un paciente con síndrome de Alport

El síndrome de Alport es un trastorno genético raro causado por mutaciones en los genes delcolágeno tipo IV, caracterizado por insuficiencia renal, hipoacusia neurosensorial y anomalíasoculares. Se presenta el caso de un paciente de 24 años con un cuadro de un día de disminución súbita de la agudeza visual en el ojo izquierdo, posterior a ruptura espontánea de la cápsula anterior del cristalino, asociado a catarata, uveítis facolítica e hipertensión ocular. En la anamnesis se encontraron antecedentes personales de hipoacusia e insuficiencia renal y, dos familiares con el diagnóstico clínico de síndrome de Alport. El heredograma sugirió una herencia dominante ligada al cromosoma X. Se inició el tratamiento tópico con prednisolona, atropina y brimonidina/timolol. Posteriormente, se realizó facoemulsificación y aspiración de restos de cristalino, con mejoría del cuadro clínico.

Isolated Anterior Lens Capsule Rupture Secondary to Blunt Trauma: Pathophysiology and Treatment.

A 25-year-old man suffered an isolated lens anterior capsular tear and mature cataract formation following blunt injury to his right eye. One week after the trauma, best-corrected visual acuity (BCVA) in the right eye was hand motion. B-scan ultrasonography showed that the lens posterior capsule was intact; no vitreous foreign body or retinal pathology were observed. Orbital computed tomography revealed narrowed anterior chamber and increased lens material volume and lens reflectivity in the injured right eye. The globe was intact and no bone fractures were observed. The cataractous lens material was removed by phacoemulsification and a foldable, acrylic, posterior chamber intraocular lens was implanted in the bag. Postoperative BCVA in the right eye was 20/20.

A Case of Anterior Lens Capsule Rupture from Blunt Ocular Trauma

A Case of Anterior Lens Capsule Rupture from Blunt Ocular Trauma

Anterior lens capsule rupture following non-penetrating ocular injury in elderly patients.

Anterior lens capsule rupture following non-penetrating ocular injury in elderly patients.

Anterior lens capsule rupture following non-penetrating ocular injury in elderly patients

Anterior lens capsule rupture following non-penetrating ocular injury in elderly patients

Circular anterior lens capsule rupture caused by blunt ocular trauma

A 16 year old male experienced blunt ocular trauma causing rupture of the anterior lens capsule and mature cataract development. The trauma was due to a stone that impacted the left eye. In an otherwise clear lens, an anterior lens capsule defect formed post-trauma that progressed to a mature cataract over four months reducing distance vision from 20/125 to hand motion. The patient underwent phacoemulsification with posterior chamber intraocular lens implantation in the left eye. One year postoperatively, the vision in the left eye increased to 20/25 without correction. This is a rare case of cataract formation due to a defect in the anterior lens capsule caused by blunt ocular trauma.

Anterior Lens Capsule Rupture Caused by Air Bag Trauma

To report a child with anterior lens capsule rupture caused by air bag inflation. A 10-year-old girl sustained a rupture of the right anterior lens capsule secondary to air bag deployment during a minor automobile accident. The evaluation included orbital ultrasound and orbital computed tomography. The right eye underwent lens aspiration with intraocular lens placement. Postoperatively, the patient did well with 20/25 best-corrected visual acuity. Our case, in which the patient's lens capsule was ruptured by air bag inflation, illustrates that air bag deployment, even in minor low-speed accidents, can cause severe blunt trauma to the eye.