Course Of Run Research Articles

Brief discussion on the characteristics of meridian sinew theory at the early era

The characteristics of meridian sinew theory at the early era have been collected. It is believed that the running courses and indications of twelve meridian sinew regions in Lingshu (Miraculous Pivot) are closely associated with Zubi Shiyimai Jiujing (Moxibustion Therapy on the Eleven Meridians of Legs and Arms) and Yinyang Shiyimai Jiujing (Moxibustion Therapy on the Eleven Meridians of Yin and Yang). Due to the attachment of twelve regular meridians, the development of its own theory is blocked. Meridian sinew theory guides the diagnosis and treatment of many dominant disorders (e.g. pain disorder and bi syndrome) with acupuncture and moxibustion. The defensive qi is circulated among meridian sinews, which is the core of meridian sinew theory. The acupoint selection relies on the meridian sinew theory at the early era, such as "consolidating muscles when they involved in disorders, using painful sites as acupoints to treat diseases" "interaction of the associated muscles" and "conducting meridian qi along with the running courses of meridians". The crack needling (one of the nine needling techniques exerted between two muscles to treat muscular pain) is adopted generally to mobilize the defensive qi so as to resist pathogens, relieve the compression in foci and promote qi and blood circulation in meridians. The rational understanding of meridian sinew theory may improve the accuracy of diagnosis and treatment of meridian sinew disorders, "reduce the pressure" on meridian theory and contribute to the enrichment of the theoretical framework of acupuncture and moxibustion.

The repeated bout effect influences lower-extremity biomechanics during a 30-min downhill run

ABSTRACT The repeated bout effect in eccentric-biased exercises is a well-known phenomenon, wherein a second bout of exercise results in attenuated strength loss and soreness compared to the first bout. We sought to determine if the repeated bout effect influences changes in lower-extremity biomechanics over the course of a 30-min downhill run. Eleven male participants completed two bouts of 30-min downhill running (DR1 and DR2) at 2.8 m.s−1 and −11.3° on an instrumented treadmill. Three-dimensional kinematics and ground reaction forces were recorded and used to quantify changes in spatiotemporal parameters, external work, leg stiffness, and lower extremity joint-quasi-stiffness throughout the 30-min run. Maximum voluntary isometric contraction (MVIC) and perceived quadriceps pain were assessed before-after, and throughout the run, respectively. DR2 resulted in attenuated loss of MVIC (P = 0.004), and perceived quadriceps pain (P < 0.001) compared to DR1. In general, participants ran with an increased duty factor towards the end of each running bout; however, increases in duty factor during DR2 (+5.4%) were less than during DR1 (+8.8%, P < 0.035). Significant reductions in leg stiffness (−11.7%, P = 0.002) and joint quasi-stiffness (up to −25.4%, all P < 0.001) were observed during DR1 but not during DR2. Furthermore, DR2 was associated with less energy absorption and energy generation than DR1 (P < 0.004). To summarize, the repeated bout effect significantly influenced lower-extremity biomechanics over the course of a downhill run. Although the mechanism(s) underlying these observations remain(s) speculative, strength loss and/or perceived muscle pain are likely to play a key role. Highlights A 30-min downhill running bout increased contact time and reduced flight time transitioning to an increased duty factor. Lower-extremity stiffness also decreased and mechanical energy absorption increased over the course of the first 30-min downhill running bout. When the same bout of 30-min downhill running was performed three weeks later, the observed changes to lower extremity biomechanics were significantly attenuated. The findings from this study demonstrated, for this first time, a repeated bout effect for lower extremity biomechanics associated with downhill running.

Research On Selection of Specialized Physical Exercises to Develop Aerobic and Anaerobic Ability for Female Students Who Specialize In Middle Distance Running Courses 38 And 37 - Faculty of Sport Training - Ho Chi Minh City University Of Sports, Vietnam

Research On Selection of Specialized Physical Exercises to Develop Aerobic and Anaerobic Ability for Female Students Who Specialize In Middle Distance Running Courses 38 And 37 - Faculty of Sport Training - Ho Chi Minh City University Of Sports, Vietnam

Super-thin ALT flap elevation using preoperative color doppler ultrasound planning: Identification of horizontally running pathway at the deep adipofascial layers

Presently, super-thin ALT flap, which is elevated above the superficial fascial plane, is gaining popularity. Although there is a huge demand for thin flaps for various types of extremity reconstruction, the technique for ALT flap thinning remains controversial. In this study, we investigated the distance and vector between penetrating points of perforators in deep and superficial fascia using color duplex and clinical measurement to suggest a reliable super-thin flap elevation technique. From June 2018 to February 2020, 44 patients with various types of defects who were treated using super-thin ALT flaps were enrolled; 69 surgically detected perforators were analyzed. All patients' flap outcomes and characteristics of the perforators were analyzed. In addition, the effects of patients' body mass index (BMI) and thickness of super-thin flap were evaluated. The average traveling length of perforator at the deep adipofascial layer (DAL) was 2.43cm, and the vector of traveling was randomly arranged. The mean thickness of super-thin ALT flap was 6.8mm. The thickness of super-thin flap was not significantly correlated with patients' BMI (ranged from 17.4 to 34.2kg/m2; p=0.183). The novel elevation technique for super-thin ALT might be useful, as evidenced by perforator traveling distance and vector in DAL. Preoperative color duplex ultrasonography is helpful to detect the running course of the perforators during elevating the flap. This anatomic concept must be considered to obtain the reliability of the super-thin ALT flap.

Great physician with absolute sincerity and carrying forward acupuncture and moxibustion: commemorating the 100th anniversary of the birth of academician CHENG Xin-nong, master of traditional Chinese medicine

The academician CHENG Xin-nong's academic thoughts and his contributions to the acupuncture and moxibustion of traditional Chinese medicine are summarized. Academician CHENG emphasizes the importance of meridian theory to acupuncture and moxibustion. He has hosted the National Climbing Program "Meridian Research", and put forward the symptom differentiation along the running course of channel and symptom differentiation based on meridian tropism. He values the guiding role of TCM theory on clinical practice of acupuncture and moxibustion, and advocates that acupoints have the same properties as traditional Chinese herb. He has established the acupuncture and moxibustion treatment based on syndrome differentiation, which includes principle, method, prescription, acupoint and technique. He is good at summarizing the acupuncture and moxibustion treatment rules of dominant diseases of TCM, and has formed his own unique acupuncture method in clinical practice: San-Cai acupuncturing method. In addition, he is one of the important founders of acupuncture and moxibustion education in the New China by pioneering early education of acupuncture and moxibustion and compiling textbooks. He is also the pioneer of international communication of acupuncture and moxibustion, carrying out international training of acupuncture and moxibustion, and spreading knowledge of acupuncture and moxibustion. He has the qualities of a great physician, dedicated to clinical practice and very kind to patients.

Analysis on the route of conception vessel and governor vessel in Huangdi Neijing (The Yellow Emperor's Inner Classic)

On the base of the analysis on the original text in Huangdi Neijing (The Yellow Emperor ¢s Inner Classic) and in association with the meridian tracing experiment results in transparent fish, rats and human body, the routes of conception vessel and governor vessel were recognized de novo. The starting site of conception vessel has been described as "the center of uterus" and "the inferior part of Zhongji (CV 3)", which refer to the same region. The running course of conception vessel includes 3 routes, named the deep abdominal route, the deep dorsal route and the superficial abdominal route. The governor vessel starts at Qugu (CV 2) on the pubis and its running course includes 4 routes, named the buttock-spine ascending route, the head-back descending route, the abdomen-face ascending route and the head-back midline route. Both the conception vessel and the governor vessel distribute on the anterior and the posterior aspects of the trunk, head and face, but they are in deep and shallow layers respectively, forming two cycles internally and externally. Such recognition is really not the pattern, known by the people, that conception vessel distributes in the front, while the governor vessel on the back.

Exploration on the diagnosis and treatment of generalized myasthenia gravis with acupuncture and moxibustion based on the study of ancient medical works

Through collecting the relevant provisions and medical cases of wei syndrome treated with acupuncture and moxibustion from ancient medical works, the diagnosis and acupoint selection in treatment of generalized myasthenia gravis (gMC) with acupuncture and moxibustion were analyzed systematically from 3 aspects, i.e. meridian differentiation, disease differentiation and syndrome differentiation. In treatment based on meridian differentiation, the acupoints are selected in the light of the running course of meridian and characteristics of meridian disorders. In treatment based on disease differentiation, the acupoints are selected in accordance with etiology, pathogenesis and transmission stages of wei syndrome. Concerning to syndrome differentiation in treatment, the acupoints are selected on the basis of therapeutic principles determined by different syndromes/patterns of wei syndrome. In modern clinical practice, the treatment for gMC should be rooted at ancient literature, thus a standardized regimen can be developed for diagnosis and treatment with acupuncture and moxibustion.

Essence of acupoints and meridians based on the studies of myofascial trigger points

Based on the modern anatomy and physiology, the referred pain of myofascial trigger points of each muscle is integrated; compared with the twelve meridians as well as conception vessel and governor vessel, the similarity of their position and running course is observed. With the current research progress of myofascial trigger points and fasciology, based on the running course of referred pain of trigger points, combined with fascia mechanics, nerve and vascular, the location of acupoints and meridians, as well as the relationship between acupoints and meridians, are discussed.

Breath Analysis of Drivers for Monitoring Their Conditions on Driving Simulator

In this study, we investigated the correlation between the condition of drivers and their expiration using a spirometer and a volatile organic compound (VOC) gas sensor on a driving simulator. Twenty-four participants with normal or corrected-to-normal vision (11 males and 13 females; age range = 19−58 years, mean age = 39.3 years) were enrolled in this study. All participants were licensed drivers who reported driving more than one day per week and never participated in any lectures for motorsports. They were equipped with air-seal masks and transducers of the spirometer (Minato Medical Science AE-310S). The spirometer measured flow rate, oxygen and carbon dioxide concentrations for output to several parameters, such as tidal volume, respiration rate, oxygen consumption, carbon dioxide excretion, end tidal oxygen and carbo dioxide etc. The masks connected to a two-way valve for dividing between inhaled and exhaled breaths (Hans Rudolph series 2600) and a gas sensor chamber for a homemade gas sensor of Pt, Pd, and Au-loaded SnO2. Resistance signal of the gas sensor affected by concentrations of volatile organic compounds (VOCs), so that the gas sensor can monitor to fluctuation of VOCs in exhaled breath. They drove a fixed-base driving simulator (Mitsubishi Precision), which had an automatic transmission system and right-hand-drive and consisted of a cockpit with a steering wheel, an accelerator pedal, a brake pedal, a side brake lever, and a shift lever, as well as a liquid crystal monitor (70-inch) and speakers (for simulated noise of engine and tires). They drove in the overtaking lane at 90−100 km/h on four different courses of varying difficulty for approximately 5 minutes each. All courses include straight roads, right-curves, and left-curves. All curves were shallow (1000R) and sharp (200R), and the frequency of curves were infrequent and frequent (0.8 and 0.2 km straight road between curves). The mean and standard deviation (SD) of all breath parameters from them were calculated during the cruising section of the courses. After driving each course, they assessed the “enjoyment” and “difficulty” of the course on a scale of one to seven. The mean and SD of all parameters were analyzed using box-and-whisker plots and two-way analysis of variance (ANOVA). There was no significant difference in the correlation between the questionnaire result of “difficulty” and each parameter of the spirometer and gas sensor. Also, the mean of all breath parameter shows no significant difference to the questionnaire result of “difficulty” and “enjoyment”. By contrast, the low (1, 2, and 3 points) and high (5, 6, and 7 points) assessment groups of "enjoyment" showed large and small SDs of all parameters from the spirometer and the gas sensor, respectively. Specifically, in the highest course difficulty (C4), there was a clear tendency between the SDs and the assessment of “enjoyment”. The box-and whisker plots show the tendency. Two-way ANOVA shows p-values classified according to the assessment, courses and, their interaction. The p-values, used in statistical study, mean the significant difference of the parameter. The parameter possesses the significant differences when the p-values of the parameter is less than 0.05. On the two-way ANOVA between “enjoyment” and courses of SDs from all parameters, the “enjoyment” and the interaction showed high significant differences with less than 0.01 of p-values. No significant differences were observed from the courses, so that there is no dependency of the running course and only the assessment of “enjoyment” was effective. Moreover, no differences were found in comparison with the parameters from the spirometer and the gas sensor so that the condition of the driver could be evaluated objectively even when only one parameter was monitored.Ref. T. Itoh, T. Sato, T. Akamatsu, W. Shin, J. Breath Res. 2019, 14, 016003. Figure 1

Lower extremity compression garments use by athletes: why, how often, and perceived benefit

BackgroundStudies on the benefits of lower extremity compression garments (CGs) have focused on their effects on post-exercise recovery and performance improvement. Less is known about why athletes actually use CGs, the frequency with which they use them, and perceived benefits from using CGs. The purpose of this study was to investigate which athletes use CGs, why athletes use CGs, when CGs are worn by athletes, and, in case of an injury or injury prevention, for which injuries CGs are used.MethodsThis cross-sectional study involved 512 athletes who used lower extremity CGs. Athletes completed a questionnaire on the type of CGs they used, and when and why they used them. They also reported their sports participation, past and current sports injuries, and the perceived benefits of using CGs.Results88.1% (n=451) of the athletes were endurance athletes and 11.9% (n=61) were non-endurance athletes. Endurance and non-endurance athletes reported running (84.7%, n=382) and obstacle course racing (24.6%, n=15) the most frequently as primary sports, respectively. The most-used CG was the compression sock (59.2%, n=303). In total, 47.5% (n=246) of the athletes used a CG primarily to prevent re-injury and 14.5% (n=74) to reduce symptoms of a current sports injury. Other primary reported aims were primary prevention (13.6%), post-exercise recovery (14.3%), sports performance improvement (8.8%), and to look good (0.2%). The point prevalence of past and current sports injuries among all athletes was 84.2 and 20.2%, respectively. The most common current sports injuries were shin and calf injuries. Many athletes “always” or “often” used their CGs during training (56.8%, n=279) and competitions (72.9%, n=264). Furthermore, almost 90% of the athletes that aimed to prevent re-injury by using CGs reported that CGs contributed to secondary injury prevention.Conclusion88% of the CG-users were endurance athletes, of which 85% were runners. All athletes mainly used CGs to prevent injury recurrence, but also to reduce symptoms of a current sports injury. A majority of the athletes reported positive perceived effects from the CGs. CGs were used more during than after sports participation.

Discussion on "guiding meridian sinew qi along with meridian running course" in treatment of meridian sinew disorders

It is to determine the effect mechanism and therapeutic method of the idea as "guiding meridian sinew qi along with meridian running course" for meridian sinew disorders so as to provide the reference for clinical treatment of these disorders. "Guiding meridian sinew qi along with meridian running course" is the summary for the approach to meridian sinew disorders by YANG Shang-shan, recorded in Huangdi Mingtang Jing (The Yellow Emperor's Acupoints Canon of Mingtang ), but the concrete statement on it had been lost. By investigating the existing ancient works, the authors discussed the specific meaning of jinqi (meridian sinew qi ), the relationship between jingjin (meridian sinew) and jingmai (meridian), the method of "guiding meridian sinew qi along with meridian running course" and its preferable acupoint selection for treatment of meridian sinew disorders with both the primary and the secondary considered.

Clinical observation on the effect of electroacupuncture treatment for chloasma in young and middle-aged women: 电针治疗中青年女性黄褐斑的临床疗效观察

ObjectiveTo evaluate the clinical effect of electroacupuncture treatment for chloasma in young and middle-aged women. MethodsSixty young and middle-aged female patients with chloasma were divided into treatment group (n = 30) and control group (n = 30) according to random number table. In the treatment group, the electroacupuncture was applied to the facial acupoints and “Vagus” in the cavity of concha in the ear. The selection of facial acupoints was relating to the running course of facial nerve trunk: Yìfēng (翳风 TE17), Shàngguān (上关 GB3)—Sīzhúkōng (丝竹空 TE 23) (Temporal branch), Xiàguān (下关 ST7)—Sìbái (四白 ST2) (Zygomatic branch), Qiānzhèng (牵正 Extra) —Quánliáo (颧髎 SI18) (Zygomatic branch), Jiāchē (颊车 ST6) —Jiāchéngjiāng (夹承浆Extra) (Buccal branch), Hégǔ (合谷LI 4). Electro-stimulation was adopted at “Vagus” in the cavity of concha in the ear (two distribution points of the vagus in the cavity of concha of each ear). The control group received conventional acupuncture (surrounding method of needling at the Ashi points in the facial lesion area and 15 acupoints which were selected in the highest frequency in the conventional acupuncture treatment). After 8 weeks of treatment, the clinical effects were compared.The total score of facial skin lesion, score of skin lesion color, score of lesion area, and effective rate of treatment for chloasma were used to evaluate the clinical effect of the two groups before and after treatment. ResultsAfter treatment, the effective rate of the treatment group was 95.00%, that of the control group was 67.50%. The effect of the treatment group was better than that of the control group, and the difference was statistically significant (χ2 = 9.928, P = 0.002). Before treatment, there was no difference in the area score, color score, and total score of skin lesions between the two groups (P>0.05). After treatment, the area score, color score, and total score of skin lesions in the treatment group were (1.05±0.64), (1.05±0.64), and (2.10±0.98) points respectively, while those in the control group were (1.38±0.63), (1.28±0.75), and (2.65±1.19) points respectively.The area score, color score, and total score of skin lesions in the treatment group were lower than those in the control group, with statistically significant differences (all P<0.05). Conclusionelectroacupuncture is more effective than conventional acupuncture in treating chloasma in young and middle-aged women.

Running barefoot leads to lower running stability compared to shod running - results from a randomized controlled study

Local dynamic running stability is the ability of a dynamic system to compensate for small perturbations during running. While the immediate effects of footwear on running biomechanics are frequently investigated, no research has studied the long-term effects of barefoot vs. shod running on local dynamic running stability. In this randomized single-blinded controlled trial, young adults novice to barefoot running were randomly allocated to a barefoot or a cushioned footwear running group. Over an 8-week-period, both groups performed a weekly 15-min treadmill running intervention in the allocated condition at 70% of their VO2 max velocity. During each session, an inertial measurement unit on the tibia recorded kinematic data (angular velocity) which was used to determine the short-time largest Lyapunov exponents as a measure of local dynamic running stability. One hundred running gait cycles at the beginning, middle, and end of each running session were analysed using one mixed linear multilevel random intercept model. Of the 41 included participants (48.8% females), 37 completed the study (drop-out = 9.7%). Participants in the barefoot running group exhibited lower running stability than in the shod running group (p = 0.037) with no changes during the intervention period (p = 0.997). Within a single session, running stability decreased over the course of the 15-min run (p = 0.012) without differences between both groups (p = 0.060). Changing from shod to barefoot running reduces running stability not only in the acute phase but also in the longer term. While running stability is a relatively new concept, it enables further insight into the biomechanical influence of footwear.

Precision vascular anatomy for minimally invasive distal pancreatectomy: A systematic review.

Minimally invasive distal pancreatectomy (MIDP) is increasingly performed worldwide; however, the surgical anatomy required to safely perform MIDP has not yet been fully considered. This review evaluated the literature concerning peripancreatic vascular anatomy, which is considered important to conduct safe MIDP. A database search of PubMed and Ichushi (Japanese) was conducted. Qualified studies investigating the anatomical variations of peripancreatic vessels related to MIDP were evaluated using SIGN methodology. Of 701 articles yielded by our search strategy, 76 articles were assessed in this systematic review. The important vascular anatomy required to recognize MIDP included the pancreatic parenchymal coverage on the root and the running course of the splenic artery, branching patterns of the splenic artery, confluence positions of the left gastric vein and the inferior mesenteric vein, forms of pancreatic veins including the centro-inferior pancreatic vein, characteristics of the left renal vein, and collateral routes perfusing the spleen following Warshaw's technique. Very few articles evaluating the relationship between the anatomical variations and surgical outcomes of MIDP were found. The precise knowledge of peripancreatic vessels is important to adequately complete MIDP. More detailed anatomic analyses and descriptions will benefit surgeons and their patients who are facing these operations.

A magyar kiegészítő nyugdíjpillér elemei és értékelése az EU elvárásainak szemszögéből

The structure, the current role, and the individual elements of the Hungarian supplementary pension scheme are presented in this study. As a Member State, it is important to follow the running courses related to the pension scheme and the supplementary pension scheme in the European Union (EU) as well as the problems declared and the answers given in the EU, which are also outlined in this paper.

Clinical Usefulness of Preoperative MCA Anatomical Scanning MRI in Thrombectomy Therapy for Acute Anterior Circulation Vessel Occlusion.

The aim of the present study was to evaluate the usefulness of the T2-weighted three-dimensional sequence method, known as "basi-parallel anatomical scanning (BPAS)-magnetic resonance imaging (MRI)," in demonstrating the running course of the obstructed middle cerebral artery (MCA) before acute mechanical thrombectomy. Patients whose M1 part and internal carotid artery (ICA) were occluded on preprocedural MRA, but well demonstrated on MCA anatomical scanning (MAS)-MRI were enrolled in this study. The MAS-MR images for patients in whom thrombectomy was performed were compared with the post-thrombectomy angiography. We compared the running course of the C1-M2 bifurcation on MAS-MRI and angiography after thrombectomy, and the results were classified into 3 groups (Excellent, Good, and Poor). A total of 13 patients (range: 54-89) were enrolled, among whom 12 underwent thrombectomy. We compared MAS-MRI and post-thrombectomy angiography in 10. On comparison between MAS-MRI and post-procedural angiography, visualization was excellent in six (60%) patients. The mean age was 75.7 years, ranging from 54 to 89, and 6 were males. 3 patients had ICA occlusion and seven had MCA occlusion. MAS-MRI was considered useful to clarify the running course of the MCA before acute mechanical thrombectomy.

Reduced-Cost Microwave Design Closure by Multi-Resolution EM Simulations and Knowledge-Based Model Management

Parameter adjustment through numerical optimization has become a commonplace of contemporary microwave engineering. Although circuit theory methods are ubiquitous in the development of microwave components, the initial designs obtained with such tools have to be further tuned to improve the system performance. This is particularly pertinent to miniaturized structures, where the cross-coupling effects cannot be adequately accounted for using equivalent networks. For the sake of reliability, design closure is normally performed using full-wave electromagnetic (EM) simulation models, which entails considerable computational expenses, often impractically excessive. Available mitigation techniques include acceleration of the conventional (e.g., gradient-based) routines using adjoint sensitivities or sparse sensitivity updates, surrogate-assisted and machine learning algorithms, the latter often combined with nature-inspired procedures. Another alternative is the employment of variable-fidelity simulations (e.g., space mapping, co-kriging), which is most often limited to two levels of accuracy (coarse/fine). This work discusses an EM model management approach coupled with trust-region gradient-based routine, which exploits problem-specific knowledge for continuous (multi-level) modification of the discretization density of the microwave structure at hand in the course of the optimization run. The optimization process is launched at the lowest discretization level, thereby allowing for low-cost exploitation of the knowledge about the device under study. Subsequently, based on the convergence indicators, the model fidelity is gradually increased to ensure reliability. The simulation fidelity selection is governed by the algorithm convergence indicators. Computational speedup (i.e., reduction in the number of EM simulations required by the optimization process to converge) is achieved by maintaining low resolution in the initial stages of the optimization run, whereas design quality is secured by eventually switching to the high-fidelity model when close to concluding the process. Numerical verification is carried out using two microstrip circuits, a dual-band power divider and a dual-band branch-line coupler, with the average savings of almost sixty percent when compared to single-fidelity optimization.

Long-range correlations and stride pattern variability in recreational and elite distance runners during a prolonged run

BackgroundAlthough movement variability and long-range correlations (LRCs) have been assessed in relation to neuropathology and aging during walking, to date only a few studies have investigated these aspects in subjects of different skill levels during prolonged overground running. Research questionWhat effect does skill level and run duration have on different stride parameters, measures of variability and long-range correlations? MethodsUsing a between-subject repeated measures design, we assessed stride mechanics, variability and LRCs in recreational and elite runners over the course of a continuous exhaustive run. All subjects ran at a fixed, pre-determined running speed relative to their maximal performance. Stride parameters were continually recorded using a single foot-mounted inertial measurement unit. It was hypothesized that a significant reduction in the strength of the LRCs would occur over the course of the run and that the observed changes would be more pronounced in the group of recreational runners. ResultsRunners maintained a consistent stride length (SL), stride time (ST) and contact time (CT) during the run, while peak impact acceleration increased. Across groups, long-range correlations significantly decreased over the course of the run, while the magnitude of the variability remained constant. LRCs did not differ significantly between groups. SignificanceThis is the first study to simultaneously investigate the effects of prolonged running and skill level on a range of stride parameters as well as stride-to-stride variability. Generally, long-range correlations were shown to be sensitive to run duration, while the magnitude of the variability did not differ between earlier and later stages of the run. The lack of a group effect on LRCs supports the idea that the mechanisms responsible for the emergence of temporal patterns in the stride pattern are not influenced by skill level.

The effect of small versus large clog size on emergency response time: A randomized controlled trial.

To assess the effect on healthcare professional emergency response time and safety of small compared to large clog size. Randomized controlled trial. The intensive care unit of a single university medical centre in The Netherlands. Intensive care medicine professionals. Participants were randomized to wear European size 38 clogs (US male size 6½, US female size 7½) or European size 47 clogs (US male size 13½, US female size 14½) clogs and were required to run a 125m course from the coffee break room to the elevator providing access to the emergency department. The primary outcome was the time to complete the running course. Height, shoe size, self-described fitness, age and staff category were investigated as possible effect modifiers. Secondary endpoints were reported clog comfort and suspected unexpected clog-related adverse events (SUCRAEs). 50 participants were randomized (25 to European size 38 clogs and 25 to size 47 clogs). Mean age was 37years (SD 12) and 29 participants (58%) were female. The primary outcome was 4.4s (95% CI -7.1; -1.6) faster in the size 5 clogs group compared to the size 12 clogs group. This effect was not modified by any of the predefined participant characteristics. No differences were found in reported clog comfort or SUCRAEs. European size 38 clogs lead to faster emergency response times than size 47 clogs. NCT04406220.

The Influence of Prolonged Running and Footwear on Lower Extremity Joint Stiffness.

The purpose of this study was to compare leg, sagittal plane knee and ankle, and frontal plane ankle stiffness over the course of a prolonged treadmill run in neutral and stability footwear. Thirteen male habitual rearfoot runners completed two biomechanical testing sessions in which they ran for 21 min at their preferred running speed in a neutral shoe, then changed either into the same neutral shoe or a stability shoe and ran a further 21 min on a force-instrumented treadmill. Three-dimensional kinematics and kinetics were recorded at the beginning and end of each 21-min interval. No differences were observed in leg stiffness between footwear conditions throughout the run (P > 0.05). Knee stiffness increased during the first 21 min (P = 0.009), whereas ankle stiffness reduced at minute 21 (P = 0.004) and minute 44 (P = 0.006). These changes were modulated by an increase in ankle joint compliance and knee joint moments. No differences were observed between footwear conditions for leg and sagittal plane lower extremity joint stiffness (P > 0.05). During the second half of the run, frontal plane ankle stiffness increased in the stability shoe but decreased in the neutral shoe (P = 0.019), attributed to reduced eversion range of motion caused by the added medial post. These results suggest that over the course of a prolonged treadmill run, shock attenuation strategies change, which may affect the knee joint.