Background: Two out-of-hospital termination-of-resuscitation rules for emergency medical service (EMS) personnel have been proposed in Canada. The first is for use by responders providing basic life support (BLS), which includes 3 criteria: event not witnessed by EMS, no shocks are administered and no return of spontaneous circulation (ROSC). The other is for use by responders providing advanced life support (ALS), which adds 2 criteria: event not witnessed by a bystander and no bystander cardiopulmonary resuscitation. Objective: To assess the validity of the 2 rules and a simple rule “AROW”, which includes 3 criteria: no use of automated external defibrillator (A), no ROSC (RO) and event not witnessed by a bystander (W), for identifying individuals with refractory out-of-hospital cardiac arrest (OHCA). Methods: A retrospective cohort study using surveillance data prospectively submitted by EMS and clinical records of 732 OHCA cases transported to our two hospitals between January, 2006, and December, 2010. Of these, 520 met the inclusion criteria. Results: Overall survival rate to hospital discharge was 9.2% ( n=48). Of 387 (74.4%) patients fulfilling the BLS rule, 2 (0.5%) survived to hospital discharge. With the other 2 rules, none of the patients survived to hospital discharge. The specificities of the BLS, “AROW” and ALS rules in identifying non-survivors were 0.958 (95% confidence interval [CI], 0.860–0.989), 1.000 (95% CI, 0.926–1.000) and 1.000 (95% CI, 0.926–1.000), respectively. The positive predictive values of the BLS, “AROW” and ALS rules for predicting non-survivors were 0.995 (95% CI, 0.981–0.999), 1.000 (95% CI, 0.987–1.000) 1.000 (95% CI, 0.969–1.000), respectively. Conclusion: The simple rule “AROW” for out-of-hospital termination-ofresuscitation showed better performance than the others in identifying OHCA patients with little chance of survival. In Japan, as EMS providers are not permitted to terminate resuscitation in the field, use of this simple clinical prediction rule may help clinicians decide whether to terminate resuscitation efforts in OHCA patients.
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