Planetary defense from asteroids via deflective means alone does not offer viable solutions in terminal scenarios where there is little warning time before impact. The PI method of planetary defense enables operation in terminal interdiction modes where there is little warning time prior to impact, but can also operate in the same extended time scale interdiction modes as made possible by traditional deflection techniques, which results in a versatile, multi-modal planetary defense capability. The method is also practical and cost-effective since it relies solely on launch vehicles and penetrator materials already available today, and thus presents itself as a logical and competitive option for planetary defense. As per the PI method, we investigate the effectiveness of rubble pile asteroid disruption and deflection via hypervelocity impacts with 10:1 aspect ratio cylindrical tungsten penetrators. We present the results of an ongoing simulation campaign dedicated to investigating the PI method, using the Lawrence Livermore National Laboratory (LLNL) arbitrary Lagrangian–Eulerian (ALE) hydrodynamics code ALE3D run with the High-End Computing Capability (HECC) at NASA Ames Research Center. We model heterogeneous rubble pile asteroids with a distribution of spherical boulders of varying initial yield strengths set within a weak binder material. We find that rubble pile asteroids of this type in the 20–100 meter-class can be effectively mitigated via 20 km/s impacts with 100–1000 kg penetrators via the coupling of the penetrator kinetic energy into the bulk material of the asteroid.