A protocol for systematic workplace investigation in the Dutch rubber manufacturing industry has been developed. The protocol, based on results and experiences of an industry-wide hygiene study, makes it possible to evaluate and control hazardous working conditions in rubber manufacturing facilities not included in the hygiene survey. Emphasis is placed on the assessment of exposure to particulates, rubber fumes, solvents and noise, and of dermal exposure to contaminants, but also of exposure to vibration, extreme climatic conditions, deleterious working postures, accident risks and unhealthy working habits. Data are collected by using questionnaires and check-lists with the analysis being performed using a large number of decision trees which are based on the best technical means of controlling hazardous working conditions.A test was carried out to compare the results of the protocol with results of the hygiene study and although this test indicated that the protocol does not generate quantifiable results, it was concluded that it could be a very useful tool for evaluating control measures, for indicating better means of controlling hazardous working conditions and for setting priorities for exposure monitoring and workplace improvement.