NEtwork MObility (NEMO) controls mobility of a number of mobile nodes in a comprehensive way using one or more mobile routers. To choose a route optimization scheme, it is very important to have a quantitative comparison of the available route optimization schemes. The focus of this paper is to analyze the degree of Route Optimization (RO), deploy-ability and type of RO supported by each class in general. The comparison shows the differences among the schemes in terms of issues, such as additional header, signaling and memory requirement. We classify the schemes established on the basic method for route optimization, and equal the schemes based on protocol overhead, such as header overhead, amount of signaling, and memory requirements. Lastly the performance of the classes of different schemes has to be estimated under norms such as available bandwidth, topology of the mobile network and mobility type.