Rous Sarcoma Virus-transformed Rat Cells Research Articles

DNA copies of viral RNA in rat cells transformed by rous sarcoma virus (RSV)

Using a modified hybridization method at least 50 p cent of the input 70 S RNA from avian tumor virus (RSV) could be annealed with DNA from RSV transformed rat cells, and only 2–3 p cent with DNA from normal cells. The mean number of viral genome copies does not seem to exeed 1 or 2 per tumor cell genome.