Roundworm Ascaris Lumbricoides Research Articles

Prevalence and intensity of soil-transmitted helminth infections among school-aged children in five districts in Uganda.

Soil-transmitted helminth (STH) infections, commonly caused by roundworms (Ascaris lumbricoides), whipworms (Trichuris trichiura), and hookworms (Necator americanus and Ancylostoma duodenale), were widespread among Ugandan schoolchildren in the late 1990s and early 2000s. Since 2003, the Ugandan Ministry of Health has administered biannual preventive chemotherapy to children aged 1-14 years to control these infections. Twenty years after the program's inception, there is scant data to show the long-term impact of these national deworming efforts. To estimate the prevalence and intensity of STH infections among 10-14-year-old primary school children, school-based, cross-sectional surveys were conducted in November 2023 across five districts (Kamwenge, Sheema, Adjumani, Lamwo, and Zombo). Sixty-five children from five schools per district were selected for inclusion. Fecal egg counts were determined using the Kato-Katz microscopy technique, performed in duplicate by trained laboratory technicians. The survey findings revealed a high prevalence of any STH infection in Kamwenge District (21.2%, 95% confidence limits (CL): 5.7%, 36.6%), while the remaining four districts exhibited lower prevalences, ranging from 0.4% (95% CL: 0.0%, 1.2%) in Adjumani District to 5.6% (95% CL: 0.0%, 11.4%) in Sheema District. The prevalence of moderate-to-heavy-intensity infections was below 1% across all districts. A. lumbricoides was identified infrequently. Hookworm infections were primarily identified in the western districts of Kamwenge and Sheema, while T. trichiura infections were common only in Kamwenge District. Hookworm and T. trichiura infections were uncommon in the northern districts of Adjumani, Lamwo, and Zombo. These surveys suggest that morbidity due to STH infections among schoolchildren may be well controlled in these five districts, as evidenced by low moderate-to-heavy-intensity infection prevalence. However, the prevalence of any intensity infection remains elevated in some districts, indicating the need for continued preventive chemotherapy distribution. A reduction from biannual treatment may be warranted in four districts, per World Health Organization recommendations.

Homoeopathy : a Weapon to Children Enemy Ascaris Lumbricoids : a Pilot Study to Study the Effectiveness of Calcarea Carbonica, Cina & Sulphur in Children with Ascariasis

The National Deworming Day is an initiative of Ministry of Health and Family Welfare, Government of India to make every child in the country worm free. This is one of the largest public health programs reaching large number of children during a short period. More than 836 million children are at risk of parasitic worm infections worldwide. According to World Health Organization 241 million children between the ages of 1 and 14 years are at risk of parasitic intestinal worms in India, also known as Soil-Transmitted Helminths (STH). Helminths (worms) which are transmitted through soil contaminated with faecal matter are called soil-transmitted helminths (Intestinal parasitic worms). Roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura) and hookworms (Necator americanus and Ancylostoma duodenale) are worms that infect people.

Astacin metalloproteases in human-parasitic nematodes.

Parasitic nematodes infect over 2billion individuals worldwide, primarily in low-resource areas, and are responsible for several chronic and potentially deadly diseases. Throughout their life cycle, these parasites are thought to use astacin metalloproteases, a subfamily of zinc-containing metalloendopeptidases, for processes such as skin penetration, molting, and tissue migration. Here, we review the known functions of astacins in human-infective, soil-transmitted parasitic nematodes - including the hookworms Necator americanus and Ancylostoma duodenale, the threadworm Strongyloides stercoralis, the giant roundworm Ascaris lumbricoides, and the whipworm Trichuris trichiura - as well as the human-infective, vector-borne filarial nematodes Wuchereria bancrofti, Onchocerca volvulus, and Brugia malayi. We also review astacin function in parasitic nematodes that infect other mammalian hosts and discuss the potential of astacins as anthelmintic drug targets. Finally, we highlight the molecular and genetic tools that are now available for further exploration of astacin function and discuss how a better understanding of astacin function in human-parasitic nematodes could lead to new avenues for nematode control and drug therapies.

Results of the archaeoparasitological analysis of soil samples from the necropolis of the 2nd c. AD settlement of Pantikapaion

In the paper, the results of an archaeoparasitological analysis of a population group from the ancient Greek city of Panti-kapaion, located in the historical centre of the modern city of Kerch (Republic of Crimea), are presented. The aim of the study is to obtain information about the parasitic diseases, state of health, nutrition, and hygiene in a part of the population of the city. The materials for the study were soil samples obtained during the treatment of the human sacra from 31 burials of the necropo-lis, dated to the 2nd century AD. In the result of the conducted investigation, the parasitic spectrum of the studied population group was determined. Eggs of three species of helminths were found. The discovery of eggs of broad tapeworm (Dibothrio-cephalus latum) in the soil samples indicates the presence in the diet of the studied population group freshwater fish that were not sufficiently thermally treated. The archaeoparasitological data from archaeological sites of a chronologically close period in the territory of the Northern Black Sea region suggests that diphyllobothriasis was a decease far from being rare in this area. The presence of eggs of human roundworm (Ascaris lumbricoides) and whipworm (Trichuris trichiura) in the samples likely indicates the challenging sanitary-hygienic environment in the city and insufficient hygienic skills in the studied group. The analysis of the archaeoparasitological data within the historical context and utilisation of the archaeopathological material from the archaeological sites in the Northern Black Sea region permitted to identify the factors that had an influence on the wide spread of geohelminths. The humid and warm climate facilitated maturation of geohelminth eggs in the soil, while the human activities concerned with the irrigation of the territory, building public water collection points, and waste buildup in the streets, in combination with the high population density, were causing the rise of the infectious hazard. The relatively high incidence rates of Trichuris trichiura and Ascaris lumbricoides may indicate a high prevalence of certain bacterial intestinal infections transmitted by the identical route. The occurrence of geohelminths, alongside the archaeological data, can indicate a low social status of the studied population group.

Correlation Between Nutritional Status, Age, and Gender on the Incidence of Soil-Transmitted Helminth Infections

Soil-transmitted helminth (STH) infections most commonly infect preschool and school-age children. The prevalence of STH infection remains high, i.e., 73 million children are infected in Indonesia. The most commonly infecting worms are roundworms (Ascaris lumbricoides), whipworms (Trichuris trichiura), and hookworms (Ancylostoma duodenale and Necator americanus). STH infection is transmitted through soil contaminated by STH eggs or larvae. Personal hygiene, availability of clean water, and defecation behavior are factors in the development of STH infection. Prolonged infection can cause malnutrition, anemia, and slow growth. This study aims to examine the association between nutritional status, age, and gender on the incidence of STH infection. This research is a descriptive-analytical study with a cross-sectional approach. Fifteen (42.86%) of 35 preschool and school-age children's stool samples were positive for Ascaris lumbricoides eggs. The nutritional status of the children was grouped into underweight, normal, and overweight. The body mass index (BMI) calculation resulted in 65.71% (23/35) underweight, 31.43% (11/35) normal, and 2.86% (1/35) overweight children. The Spearmen test shows that there is no significant correlation between nutritional status (p=0.517), age (p=0.614), and gender (p=0.637) on STH infection.

Investigating the association between intestinal parasite infection and cribra orbitalia in the medieval population of Cambridge, UK

ObjectiveCribra orbitalia is believed to be a skeletal indicator of chronic anaemia, scurvy, rickets or related metabolic diseases. It has been suggested that it may be used as a proxy indicator for intestinal parasite infection, as parasites often cause anaemia today. Our aim is to investigate this association in the medieval population of Cambridge, UK. MaterialsIndividuals excavated from the cemeteries of the Augustinian friary and All Saints by the Castle parish church, and aged from 7 to adulthood. MethodsWe undertook parasite analysis of the pelvic sediment and control samples of 46 burials with intact orbital roofs. ResultsHuman roundworm (Ascaris lumbricoides) and/or whipworm (Trichuris trichiura) were identified in the pelvic sediment of 22 individuals, and cribra orbitalia noted in 11 individuals. Barnards test showed no association between parasite infection and cribra orbitalia (p = .882). ConclusionWe found no association between infection and cribra orbitalia infection in this medieval adult population, calling into question this hypothesis, at least for adults. SignificanceHigh or low cribra orbitalia prevalence in adults should not be used to infer rates of intestinal parasite infection. LimitationsThe individuals in the study were over the age of 7, with no younger children. It is possible that only parasites which cause marked anaemia (such as hookworm, schistosomiasis or malaria) may cause cribra orbitalia, while less marked anaemia from roundworm and whipworm may not do so. Suggestions for Further ResearchRepeating this study in younger children, when most cribra orbitalia appears to form.

Comparison Of Feat Examination Results Using Direct Slide And Sedimentation Methods For Detecting Soil Transmidet Helmint (STH) Worm Infection In Primary School Students

The worms are parasitic infections that occur frequently and are estimated to infect 1-45 billion individuals worldwide. There are several types of worms that infect humans, namely roundworms (Ascaris lumbricoides), whipworms (Trichuris trichura), and hookworms or hookworms (Ancylostoma duodenale and necator americanus). The method used in this research is descriptive analytical method, which is the method used to view the description of the examination results from a sample. The population of this study was elementary school students with a sample of 50 students. Based on the results of the study using the direct slide method, negative results were obtained with a percentage of 100% with a total frequency of 50 students. If using the sedimentation method, 3 students were infected with Ascaris lumbrichoides with a percentage of 6.0% and 47 students were not infected with a percentage of 94.0% with a total sample of 50 students. Based on the results of the research using the direct slide and sedimentation methods, the results showed that the results of the two methods used were influenced by different sensitivity.

Prevalence and intensity of soil-transmitted helminth infections in Uganda: Results from population-based prevalence surveys in five districts.

Soil-transmitted helminth (STH) infections are caused by roundworms (Ascaris lumbricoides), whipworms (Trichuris trichiura), and hookworms (Necator americanus and Ancylostoma duodenale). In Uganda, baseline surveys conducted during the late 1990s and early 2000s suggested STH infections were common, with prevalence >50% among surveyed schoolchildren. In 2003, a national program was launched with mass preventative chemotherapy (PC) and health education for children 1-14 years old. Little evidence is available to show the impact of national deworming. We conducted population-based, cross-sectional household surveys in five districts (Buikwe, Kassanda, Kiryandongo, Kisoro, and Rubanda) in March and May 2022. Our primary objective was to estimate STH prevalence by species due to infections of any intensity and infections of moderate-to-heavy intensity among preschool-aged children (PSAC, 1-4 years old), school-aged children (SAC, 5-14 years old), and women of reproductive age (WRA, 15-49 years old). Laboratory technicians used duplicate Kato-Katz microscopy to determine fecal egg count. Overall, 3,352 PSAC; 3,884 SAC; and 1,226 WRA provided stool samples. The prevalence of any infection remained high in Kisoro at or above ~50% within all risk groups. In other districts, the prevalence of any infection ranged from approximately 5 to 16% among PSAC, 6 to 23% among SAC, and 12 to 19% among WRA. Moderate-to-heavy intensity infection prevalence was highest in Kisoro (~15-26%), followed by Rubanda (<5%), and was ≤1% in other districts. A. lumbricoides and T. trichiura infections were largely confined to Kisoro and Rubanda, whereas hookworm was most common in other districts. The STH prevalence has decreased markedly in three districts in Uganda. Based on our findings, the national deworming program should consider decreasing PC distribution frequency in these districts per the World Health Organization guidelines. Efforts are needed to understand why the Kisoro and Rubanda districts did not demonstrate similar gains.

First molecular data on the human roundworm Ascaris lumbricoides species complex from the Bronze and Iron Age in Hallstatt, Austria

Palaeoparasitological studies can provide valuable information on the emergence, distribution, and elimination of parasites during a particular time in the past. In the prehistoric salt mines of Hallstatt, located in the Austrian Alps, human faeces have been conserved in salt. The aim of this study was to recover ancient DNA of intestinal parasites from these coprolites. Altogether, 35 coprolites from the Hallstatt salt mines, dating back to the Bronze Age mining phase (1158–1063 BCE) and the Iron Age mining phase (750–662 BCE), respectively, were analysed by microscopy and molecular methods. In 91% of the coprolite samples, eggs of soil-transmitted helminths (STH), namely of Trichuris and/or Ascaris were detected by light microscopy. The Ascaris eggs were exceptionally well preserved. For further analysis, DNA was extracted from the palaeofaecal samples and species-specific primers targeting different genes were designed. While amplification of Trichuris DNA remained unsuccessful, sequence data of A. lumbricoides species complex were successfully obtained from 16 coprolites from three different genes, the mitochondrial cytochrome c oxidase subunit 1 gene (cox1), the mitochondrial cytochrome B gene (cytB) and the mitochondrial NADH dehydrogenase subunit 1 gene (nadh1). Importantly, these included two Ascaris sequences from a coprolite from the Bronze Age, which to the best of our knowledge are the first molecular data of this genus from this period.

Testing of sand from recreational areas and sandpits in Warsaw, for presence of Ascaris Lumbricoides and Toxocara spp.

Improper maintenance of the cleanliness of sand in sandboxes can be a source of human pathogenic helminths, including Toxocara spp., Enterobius vermicularis, Ascaris lumbricoides, leading to parasitic infections. The purpose of this study was to evaluate the sanitary condition of sandboxes in playgrounds and recreational areas in Warsaw for the presence of Human roundworm (Ascaris lumbricoides) and Toxocara spp. in sand. 450 sand samples from 90 sandboxes in the city of Warsaw were analyzed. The flotation method was used for the study, and the material was evaluated using a light microscope. RESULTS. The conducted examinations did not reveal the presence of parasite eggs, indicating that hygiene rules were observed and appropriate recommendations were followed. The analyzed sand samples are free of the tested parasites.

Giardia duodenalis and dysentery in Iron Age Jerusalem (7th-6th century BCE).

The aim of this study was to determine if the protozoa that cause dysentery might have been present in Jerusalem, the capital of the Kingdom of Judah, during the Iron Age. Sediments from 2 latrines pertaining to this time period were obtained, 1 dating from the 7th century BCE and another from the 7th to early 6th century BCE. Microscopic investigations have previously shown that the users were infected by whipworm (Trichuris trichiura), roundworm (Ascaris lumbricoides), Taenia sp. tapeworm and pinworm (Enterobius vermicularis). However, the protozoa that cause dysentery are fragile and do not survive well in ancient samples in a form recognizable using light microscopy. Enzyme-linked immunosorbent assay kits designed to detect the antigens of Entamoeba histolytica, Cryptosporidium sp. and Giardia duodenalis were used. Results for Entamoeba and Cryptosporidium were negative, while Giardia was positive for both latrine sediments when the analysis was repeated three times. This provides our first microbiological evidence for infective diarrhoeal illnesses that would have affected the populations of the ancient near east. When we integrate descriptions from 2nd and 1st millennium BCE Mesopotamian medical texts, it seems likely that outbreaks of dysentery due to giardiasis may have caused ill health throughout early towns across the region.

Efek Antelmintik Ekstrak Metanol Kulit Batang Nangka (Artocarpus heterophyllus) terhadap Cacing Ascaris lumbricoides

Jackfruit (Artocarpus heterophyllus) is a type of plant that grows in Indonesia which functions as a food ingredient and as traditional medicine. Generally, this genus contains prenylated flavonoid compounds. This study aimed to determine the anthelmintic effect of jackfruit bark extract against Ascaris lumbricoides worms by utilizing total maceration with methanol solvent as the extraction method, which yielded 6.61%. Roundworm Ascaris lumbricoides are found in pig intestines. The samples were divided into 5 groups, including positive control of 250 mg combantrin solution, negative control of NaCMC and a treatment group of jackfruit bark extract with a concentration of 1%, 3%, and 5%. Each group consisted of three worms, incubated at 37oC for 24 hours with a 6 hours interval. The results showed that at a concentration of 5%, a jackfruit bark extract was efficient as an anthelmintic caused two worms to lyse at 6 hours and one at 12 hours.

Continuity in intestinal parasite infection in Aalst (Belgium) from the medieval to the early modern period (12th-17th centuries)

ObjectiveTo characterize patterns in the taxonomic diversity of parasites infecting the population of Aalst, Belgium, between the 12th and 17th centuries. Materials14 sediment samples from seven cesspits dated 1100–1700 CE. MethodsDigital light microscopy and Enzyme-linked immunosorbent assay (ELISA). ResultsWe identified eggs of four species of helminths: whipworm (Trichuris trichiura), roundworm (Ascaris lumbricoides), Echinostoma fluke and Dicrocoelium fluke. ELISA results for protozoal parasites were negative. ConclusionsTaxonomic diversity of parasite infections remained constant from the 12th to the 17th centuries. Roundworm and whipworm, spread by poor sanitation, were dominant. Two species of zoonotic parasites were also identified, including for the first time ever in the Low Countries the Echinostoma fluke, which may have been spread by eating uncooked freshwater animal foods. SignificanceAnalysis of sediment samples spanning such a broad chronology (six centuries) from a single city offers the opportunity to track diachronic change, which is rare in paleoparasitological studies. LimitationsWe were unable to acquire samples from cesspits dating to the 14th century. Suggestions for further researchAdditional data from other Low Countries towns may strengthen the patterns identified in this paper. A similar approach can be used to investigate towns in different regions of the world.

Effect of Azadirachta indica on Pheretima posthuma

Soil-transmitted helminth (STH) infections are worm infections that can be facilitated by one or more intestinal parasitic worms such as roundworm (Ascaris lumbricoides), hookworm (HW; Ancylostoma duodenale and Necator americanus), threadworm (Strongyloides stercoralis), and whipworm (Trichuris trichiura). More than two billion people are thought to be affected by STH infections globally. Eggs in human feces, which are commonly seen in low-resource countries, spread STH by contaminating the soil and water in unhygienic places. The transmission is by human exposures to the infective stages, either by direct skin penetration or through ingestion that could result in a serious illness, though infections remain asymptomatic in the majority of cases with light-intensity infections. Azadirachta indica, usually called Indian neem, has been extensively used in ayurveda, unani, and homoeopathic medicine since time immemorial. A. inidica has been used ethnopharmacologically to treat diseases such as cancer, diarrhea, gastric ulcers, wound infections, trypanosomiasis, malaria, and tuberculosis. A. indica leaf extracts in methanol were tested for their ability to treat Pheretima posthuma worms. From the experimental outcome, we find that the leaf extracts of A. indica, when compared to the usual medication, the plant was found to exhibit substantial anthelmintic activity. The present research concludes that neem has a variety of bioactive compou

A reverse vaccinology approach identifies putative vaccination targets in the zoonotic nematode Ascaris.

Ascariasis is the most prevalent helminthic disease affecting both humans and pigs and is caused by the roundworms Ascaris lumbricoides and Ascaris suum. While preventive chemotherapy continues to be the most common control method, recent reports of anthelminthic resistance highlight the need for development of a vaccine against ascariasis. The aim of this study was to use a reverse vaccinology approach to identify potential vaccine candidates for Ascaris. Three Ascaris proteomes predicted from whole-genome sequences were analyzed. Candidate proteins were identified using open-access bioinformatic tools (e.g., Vacceed, VaxiJen, Bepipred 2.0) which test for different characteristics such as sub-cellular location, T-cell and B-cell molecular binding, antigenicity, allergenicity and phylogenetic relationship with other nematode proteins. From over 100,000 protein sequences analyzed, four transmembrane proteins were predicted to be non-allergen antigens and potential vaccine candidates. The four proteins are a Piezo protein, two voltage-dependent calcium channels and a protocadherin-like protein, are all expressed in either the muscle or ovaries of both Ascaris species, and all contained high affinity epitopes for T-cells and B-cells. The use of a reverse vaccinology approach allowed the prediction of four new potential vaccination targets against ascariasis in humans and pigs. These targets can now be further tested in in vitro and in vivo assays to prove efficacy in both pigs and humans.

Soil-transmitted helminths detected from environmental samples in a campus of southern Brazil

Soil harbours enormous biodiversity, essential for maintaining environmental and human health. However, soil can also be a reservoir of various parasitic pathogens, such as soil-transmitted helminths (STH). We evaluated the presence of STH (e.g., hookworms, roundworms and whipworms) in soil samples collected at twenty points within the perimeter of Campus do Vale (a university campus belonging to the Federal University of Rio Grande do Sul - UFRGS), during 2022 winter season. Considering the One Health perspective, human, animal and environment-related data from each sampling point were collected. All soil samples showed nematode larvae, representing natural components of soil biodiversity. Considering STH eggs, 35% (n = 7) of soil samples showed hookworm eggs (e.g., from Necator americanus or Ancylostoma duodenale), 10% (n = 2) showed roundworm (Ascaris lumbricoides) eggs, and 5% (n = 1) showed whipworm (Trichuris trichiura-like) eggs. Of note, 10% of the sampling points showed the presence of rhabditiform hookworm larvae, 5% showed Strongyloides stercoralis rhabditiform larvae and 5% had the presence of filariform hookworm larvae, indicating a risk of human percutaneous infection. The significant people circulation in Campus do Vale, in association with other environment-related factors, help to explain the prevalence of STH observed in this study.

Iron deficiency and soil-transmitted helminth infection: classic and neglected connections.

Beyond participating in the oxygen transport by red blood cells, iron is an essential micronutrient and contributes to different physiological pathways and processes, such as cell proliferation, DNA repair, and other homeostatic functions. Iron deficiency affects millions of people, especially children and pregnant women. The consequences of iron deficiency are diverse, including inadequate child development, impaired cognition, and reduced productivity. Several factors contribute to iron deficiency, such as iron-poor diet, genetic factors, and infection with soil-transmitted helminths (STHs), especially roundworms (Ascaris lumbricoides), hookworms (Necator americanus and Ancylostoma duodenale), and whipworms (Trichuris trichiura). This review updates and summarizes the role of STHs as drivers of iron deficiency. Also, the poorly explored connections between STH infection, geophagia (a pica manifestation), immune response, and iron deficiency are discussed, highlighting how iron deficiency may act as a risk factor for infections by STHs, in addition to being a consequence of intestinal parasitic infections. Finally, strategies for control and management of iron deficiency and STH infection are described.

Using Routinely Collected Health Records to Identify the Fine-Resolution Spatial Patterns of Soil-Transmitted Helminth Infections in Rwanda.

Background. Soil-transmitted helminths (STH) are parasitic diseases with significant public health impact. Analysis is generally based on cross-sectional prevalence surveys; outcomes are mostly aggregated to larger spatial units. However, recent research demonstrates that infection levels and spatial patterns differ between STH species and tend to be localized. Methods. Incidence data of STHs including roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura) and hookworms per primary health facility for 2008 were linked to spatially delineated primary health center service areas. Prevalence data per district for individual and combined STH infections from the 2008 nationwide survey in Rwanda were also obtained. Results. A comparison of reported prevalence and incidence data indicated significant positive correlations for roundworm (R2 = 0.63) and hookworm (R2 = 0.27). Weak positive correlations were observed for whipworm (R2 = 0.02) and the three STHs combined (R2 = 0.10). Incidence of roundworm and whipworm were found to be focalized with significant spatial autocorrelation (Moran’s I > 0: 0.05–0.38 and p ≤ 0.03), with (very) high incidence rates in some focal areas. In contrast, hookworm incidence is ubiquitous and randomly distributed (Moran’s I > 0: 0.006 and p = 0.74) with very low incidence rates. Furthermore, an exploratory regression analysis identified relationships between helminth infection cases and potential environmental and socio-economic risk factors. Conclusions. Findings show that the spatial distribution of STH incidence is significantly associated with soil properties (sand proportion and pH), rainfall, wetlands and their uses, population density and proportion of rural residents. Identified spatial patterns are important for guiding STH prevention and control programs.

Level of Community Knowledge About Medicine for Adult Worms in Baru Village Siantar Utara District

Worm disease can cause problems because it causes loss of carbohydrates and protein as well as blood loss, thereby reducing the quality of human resources. The largest nematodes and infecting hundreds of millions of people are roundworms ( Ascaris lumbricoides ), whipworms ( Trichuris trichiura ), and hookworms ( Ancylostoma duodenale and Necatoramericanus ). These types of worms are widely found and easy to grow in tropical and subtropical Asia. And public awareness of the disease is still low. In particular, the new Kelurahan is one of the kelurahan located in Pemangsiantar, which is one of the kelurahan with a dense population, with various age levels. Therefore the authors measure the level of public knowledge of adult worm disease. From the results of the research that the author did using questionnaire data using respondent data with sample data as many as 30 respondents, it was found that the new urban village had a good level of knowledge about the disease, the data can be seen from testing data using the SPSS application with a level of correlation accuracy. the good one.

Soil-Transmitted Helminths and Anaemia: A Neglected Association Outside the Tropics.

Anaemia is an important cause of morbidity and mortality globally. Among infectious agents responsible for anaemia, helminthic infections are often neglected, particularly in non-endemic countries. However, they should not be neglected in this setting, as international travel and migration are on the rise. In this narrative review, we aimed to describe soil-transmitted helminths as a cause of or contributing factor to anaemia, focusing on hookworms (Necator americanus and Ancylostoma duodenale), the whipworm (Trichuris trichiura), the roundworm (Ascaris lumbricoides), and the threadworm (Strongyloides stercoralis). A general review on the epidemiology, lifecycle, and clinical spectrum of anaemia is proposed, with a special focus on helminthic infections’ association with anaemia as well as the diagnostic approach, which are both particularly important in non-endemic settings.