The objective of this study was to evaluate the effect of (Er,Cr: YSGG) laser debonding treatment on optical properties and surface roughness of veneers made of different ceramic materials. Thirty bovine incisors were prepared to receive laminate veneers and divided into three groups (n = 10) according to ceramic material where group (E): IPS e.max CAD, group (S): Vita Suprinity, and group (C): Celtra Duo. Blocks were sectioned into 0.5mm thickness plates and cemented on the labial surface of incisors using resin cement. The Er,Cr: YSGG laser was applied to each specimen at 4.5W and 25Hz for group E and at 6W and 25Hz for groups S and C. Color change (△E00), translucency parameter (TP) and surface roughness in µm (Ra) values were measured and calculated before and after laser treatment. Data were analyzed using two-way mixed model ANOVA at a significance level of p < 0.05. The highest mean △E00 value was recorded in group E (1.35 ±0.09) followed by group S (1.08 ±0.16) and then group C (0.93 ±0.10) with a significant difference between them (p<0.001). All groups exceeded the perceptibility threshold but remained below the acceptability threshold. No statistically significant difference was found in TP except for group E (p=0.019). Ra values after laser debonding showed significantly higher values than before laser treatment in all three groups (p<0.001). Er,Cr: YSGG laser can be safely used for debonding ceramic veneers without altering the optical properties but it does increase the roughness of debonded ceramic restorations.