ABSTRACT In this article, we demonstrate that a single station can be used to measure the dynamic properties of a structure. The station includes a collocated accelerometer and rotational sensor, hence, can record both three-component translation and three-component rotation and is referred to as the 6C-station within this study. The key advantage of this approach is to provide a fast and simple path to a comprehensive structural health monitoring characterization that is comparable to the use of a traditional approach using a horizontal array of three-component accelerometers. The deployment of newly developed high-quality rotational sensors allows the direct measurement of structural rotations, facilitating the extraction of structural mode shapes. In this work, we show how an established system identification tool, stochastic subspace identification, can be applied to the 6C-station data and characterize modal properties and structural response. Our results are verified and contrasted against standard horizontal and vertical array configurations. The Prime Tower, a high-rise structure in Zürich, serves as a case study. A structural characterization of this building is presented for the first time. We show that a 6C-station is capable of defining the frequencies of this stiff high-rise building with a fidelity that is on par with a five-sensor horizontal array. The mode shapes of the roof can be precisely determined with a confidence margin that is comparable to conventional sensing array solutions. However, the effectiveness of using only a 6C-station is determined by the noise level of the sensors—in particular, the rotational seismometer needs to be of high quality. The results indicate that, owing to the collocation measurement of translation and rotation, a 6C-station can deliver a comprehensive structural monitoring solution with minimum time, effort, and footprint.